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Cheatography

Action, Indication, CI, C, AE, DI, & NI

Action

Blocks Vitamin K at sites of action

Indica­tions

Stroke/TIA
A-fib
DVT
-May be used with children
-Decrease dose with elderly patients

Contra­ind­ica­tions

Blood disorders
Hepatic Disease
GI Ulceration
All above diseases + warfarin can cause fatal bleeding

BLACK BOX WARNING

Majori­Ble­eding

Pregnancy Category X

Fetal Warfarin Syndrome (FWS)
Develo­pmental delays
 
Low birth weight
 
Poor growth
 

Adverse Effect

Bleeding

Drug Intera­ctions

Increase effects of warfarin:
Decrease Warfarin Effects:
-NSAIDS
-Birth Control
-Bactrim
-Spiro­nol­actone
-PPIs
-Haldol
 
-H2 blockers
 
-Aprep­itant

Admini­str­ation

Half-life = 24-72 hrs
Remains in system 4-5 days
PO at night at the same time
*highly protein bound therefore absorption is heavily impacted by food and protein levels in body
 

Nursing Interv­entions

Monitor Labs: CBC & PT/INR
Administer antidote if OD occurs
Vitamin K
Educate pt. about diet
Instruct patient to eat the same amount of foods containing vitamin K every week
Emaciate Patients
Not DOC because the decrease protein in blood increase risk of toxicity

Expected Lab values

CBC
no indication of thromb­ocy­topenia
PT
18-30 seconds
INR
2-3
 

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