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A&P Chapter 2: Chemical Basis of Life Cheat Sheet by

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Essential Elements

Bulk Elements
required by the body in large amounts
Oxygen
Carbon
Hydrogen
Nitrogen
Phosphorus
Sulfur
Trace Elements
required in small amounts
Copper
Iodine
Iron
Ultratrace Elements
required in very small amounts
Arsenic
Boron
Nickel
Silicon
Tin

Principle Elements in the Human Body

Element
% of Body Weight
Function
Oxygen (O)
65%
Component of water, essential for respir­ation
Carbon (C)
18.6%
Found in all organic molecules
Hydrogen (H)
9.7%
Component of water and most compound in the body
Nitrogen (N)
3.2%
Found in proteins and nucleic acids
Calcium (Ca)
1.8%
Found in bones and teeth, needed for nerves and muscle contra­ction, blood clotting
Phosphorus (P)
1%
Found in bones, teeth, ATP
Potassium (K)
0.4%
Necessary for membrane function, nerve impulses, and muscle contra­ctions
Sodium (Na)
0.2%
Necessary for membrane function, nerve impulses, and muscle contra­ctions
Chlorine (Cl)
0.2%
Important for membrane function and water absorp­tion, major component of stomach acid
Sulfur (S)
0.04%
Found in many proteins
Iron (Fe)
0.007%
Essential for oxygen transport
Iodine (I)
0.0002%
Component of hormones of the thyroid gland

Ions

Name
Chemical Symbol
Sodium
Na+
Potassium
K+
Calcium
Ca2+
Chlorine
Cl-
Bicarb­onate
HCO3-

Catabolism

Catabolism (Decom­pos­ition): breaks molecules into smaller fragments

Anabolism

Anabolism (Synth­esis): assembles larger molecules from smaller ones
 

Exchange Reactions

Exchange Reactions (repla­cem­ent): reacting molecules are rearranged

Reversible Reaction

Inorganic vs Organic Molecules

Inorganic
No C and H together
Smaller molecules
Dissociate in water
Water, oxygen, carbon dioxide, and salts
Organic
Contain C and H
Larger molecules
Dissolve in water
Carboh­ydr­ates, lipids, proteins and nucleic acids

Organic Building Blocks

Carboh­ydrates

Contains C, H, and O (often end in the suffix "­-os­e")
1:2:1 ratio
Monosa­cch­arides and Disacc­harides (simple sugars): provide energy
      - Monosa­cch­aride examples: glucose, fructose,
        galactose
      - Disacc­haride examples: sucrose, maltose,
         ­lactose
Polysa­cch­arides: store glucose
      - Examples: glycogen (in liver and muscle)
Glycop­roteins and Glycol­ipids: on cell surfaces, aid in cell commun­ication and recogn­ition (ID tags)
      - ex. MHC proteins, T-cell receptors, blood type

Carboh­ydrate Structures

Trigly­cerides

Functions:
      - Used primarily for energy storage
      - More energy rich than glucose
      - Cushions and insulates the body and nerves
        (myelin sheath)
Structure:
      - Made of 1 glycerol and 3 fatty acids
            - Saturated fats contain three saturated fatty
               ­acids
                  - Saturated = all single C to C bonds
                    (saturated in hydrogen)
                  - Mostly solid and come from animals
            - Unsatu­rated fats contain at least one
               ­uns­atu­rated fatty acid
                  - Unsatu­rated = at least one double C to
                     C bond (causes kinks in the chain)
                  - Mostly liquid and come from plants

Trigly­ceride Structure

The first two fatty acid chains are saturated while the third fatty acid chain is unsatu­rated
 

Phosph­olipids

Function:
      - Major component of cell membranes
      - Helps provide selective permea­bility
         ­(water barrier)
Structure:
      - Made of 1 glycerol, 2 fatty acids, and 1
         ­pho­sphate
      - Hydrop­hilic head and hydrop­hobic tails
         ­(am­phi­pathic)

Phosph­olipid Structure

Steroids

Function:
      - Synthesize sex hormones
      - Choles­terol: Needed for vitamin D and bile
         ­pro­duction
            - HDL "good kind" goes to the liver
            - LDL "bad kind" gets deposited on artery
               ­walls
Structure:
      - Four connected rings of carbon, hydrop­hobic

Steroid Structure

Proteins

Functions:
      - Structure and support: muscle, ligaments,
         ­fin­ger­nails, hair, skin
      - Last resort energy source
      - Hormones
      - Receptors
      - Antibodies
      - Enzymes
Structure:
      - Made of amino acids (20 in human body)
      - Amine group, carboxyl group, variable R group
      - Amino acids held together with peptide bonds
      - Must have specific shape to function correctly

Protein Structure

Nucleic Acids

Function:
      - DNA (deoxy­rib­onu­cleic acid): encodes genetic
         ­inf­orm­ation
            - Provides instru­ctions for making proteins
      - RNA (ribon­ucleic acid): helps decode DNA
Structure:
      - Contains the elements CHONP
      - Made of nucleo­tides

Nucleic Acid Structure

 

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