Cheatography
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Used in treatment of benign prostatic hypertrophy and pattern hair loss. Reduces risk of prostate cancer.
5 Alpha Reductase InhibitorsPrototype Med | finasteride (Propecia and Proscar) | Other Meds | dutasteride (Avodart) |
Action: Act by inhibiting the enzyme 5 alpha reductase which chages testosterone into 5 alpha dihydrotestosterone or DHT in the prostate gland. Therapeutic UseTreatment of benign prostatic hypertrophy (also reduces the risk of prostate cancer) | Treatment of male pattern hair loss (Propecia) |
Adverse Drug ReactionsReduced libido and ejaculate volume | Reduced prostate-specific antigen (PSA) levels | Gynecomastia (males) |
Nursing InterventionsTell clients about the possibility of reductions in libido and ejaculate volume. | Obtain a baseline PSA level and monitor periodically. | Expect PSA levels to decline with therapy. | Evaluate any increases in PSA level, as they may indicate prostate cancer or nonadherence to therapy. | Monitor for breast enlargement. | Evaluate if there is concern for body image. |
| | AdministrationTake orally, with or without food. | Crush the tablets if needed. | Expect drug therapy to be lifelong. | Ensure that women do not handle the drug, especially if crushed, due to the possibility of transdermal absorption. | Expect therapeutic effects to take 6 to 12 months. |
Patient EducationExpect decreases in libido and ejaculate volume. | Undergo regular prostate cancer screenings. | Report breast enlargement. |
ContraindicationsPregnancy (teratogenic) | Female, children |
PrecautionsLiver impairment | Obstructive uropathy |
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