Structure
Spherical Shaped |
Enveloped virus |
One lipid membrane |
Outer layer |
Corrugated due to protrusions |
Internal Core |
Dumbbell shaped |
Lateral bodies |
Two present in the concavities between outer layer and Core |
Outer core wall |
Palisade structure with T-shaped spike proteins |
Inner Core wall |
Smooth |
Proteins
Attachment |
A17, A25, A26, A27, D8, H3 |
Entry |
Entry Fusion Complex-A16, A21, A28, F9, G3, G9, H2, I2, J5, L1, L5, O3 |
Redox active proteins |
E10, A2.5, and G4 |
Phosphorylation |
Kinase- F10 & B1 |
Dephosphorylation |
Phosphotase - H1 |
Proteolytic processing |
proteinase - I7 |
Poster By
Bommana Chanakya |
Sushma Bhandarkar |
213501003 |
213501004 |
Poster By
Bommana Chanakya |
Sushma Bhandarkar |
213501003 |
213501004 |
|
|
Genome Organisation
Terminal Regions |
Has ITRs with secondary hairpin loop structures that connect two DNA strands and contains the variable genes that are responsible for host cell interactions |
Central Regions |
Conserved genes responsible for replication and morphogenesis |
Proteins
Attachment |
A17, A25, A26, A27, D8, H3 |
Entry |
Entry Fusion Complex - A16, A21, A28, F9, G3, G9, H2, I2, J5, L1, L5, O3 |
Redox active proteins |
E10, A2.5, and G4 |
Phosphorylation |
Kinase - F10 and B1 |
Dephosphorylation |
Phosphatase - H1 |
Proteolytic processing |
Proteinase - I7 |
Protein
Early Gene Proteins |
Inducing proliferation of neighbouring cells |
| |
Counteracting host immune defences |
| |
Some proteins can induce a second uncoating reaction thereby releasing the viral genome from the core |
| |
Mediating replication of the genome |
| |
Protiens In Replication |
Viral DNA polymerase |
| |
Helicase-primase |
| |
Uracil DNA glycosylase |
| |
Single-stranded DNA-binding protein |
| |
DNA ligase |
| |
Holliday junction resolvase |
| |
Proteins In Transcription |
RNA polymerase |
| |
ETF |
| |
Capping enzyme |
| |
VITF-3 |
| |
VLTF-1, VLTF-2, VLTF-3, VLTF-4 |
| |
Release factor Elongation factor |
| |
Poly(A) polymerase |
| |
DNA topoisomerase |
|
|
Replication process
Attachment |
Entry |
Early Gene Transcription |
DNA Replication |
Intermediate Gene Transcription |
Late Gene Transription |
Assembly |
Release |
|
Created By
Metadata
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