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DPP-4 Inhibitor Cheat Sheet by

Drug info for Stigaliptin

Prototype

Stigal­iptan

Action

Slows down GLP-1
Prolongs effects of insulin secretion
Decreases glucagon
Slows Gastric Emptying

Indication

Used in patients with Type 2 Diabetes

Contra­ind­ication

Do not give to patients with GI disorders such as Gastro­paresis
 

Adverse Effects

Pancre­atitis
Increase creatinine levels
Upper Respir­atory Infection

Drug Intera­ctions

Medica­tions that slow the GI tract such as Loperamide or Opioids
Can cause Digoxin toxicity

Nursing Interv­entions

Administer PO once daily
Monitor A1C, Creati­nine, Lipase, & Amylase
Monitor for pancre­atitis

Normal Lab Values

A1C
Goal: <6.5
Lipase
0-160
Amylase
23-85
Creatinine
0.5-1.5
 

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