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Glucocorticoids & DMARDs Cheat Sheet by

high yield about glucocorticoids

GC for RA

Short acting (Prefe­rred))
Cortisone
Hydroc­ort­isone
Interm­ediate acting
Prednisone
Prednisolone
Long acting
Betame­thasone
Dexamethasone
!!!HPA suppresion
REMEMBER
Steroid = S = -sone

Anti-i­nfl­amm­atory effect & mechanism

  

Adverse effect & Contra­ind­ication

Glaucoma
Lunacy (psychotic episode)
CI: Epilepsy
Ulcer (peptic)
CI: Peptic ulcer
Cushing syndrome
Opport­unistic infection
CI: Immuno­sup­presive (eg: TB)
Cataract
for long term use
Osteop­orosis
CI: Osteop­orosis
Retention sodium and water
CI: CHF, HpT, renal failure
Telang­ectasia ( dilated or broken blood vessels located near the surface of the skin or mucous membranes.
Insulin resistance
CI: Diabetes melitus
Outgrowth retard­ation
in children
Delayed wound heling
Supress HPA axis
long acting very potent GC:
Betamethasone
Dexamethasone
REMEMBER
GLUCOC­ORT­ICOIDS
  

cDMARDs

Leflun­amide (Arava)
AE: Hepato, HpT
Sulfas­alazine
Safe in pregnancy
AE: hypers­ens­iti­vity, hepato
Cyclos­porin
AE: GI, HpT
Hydrox­ych­lor­oquine
AE: Eye, skin hyperp­igm­ent­ation
Methot­rexate
AE: GI, Hepato
REMEMBER
LiSa Can you give Her Methot­rexate

NOTES
- Only Sulfan­azide is safe in pregnancy (S = Sulfan­azide = Safe in pregnancy - Sensitive)
- First line: M

bDMARDs

extra

Adverse effect & Precaution

Reacti­vation TB
TB screening
Opport­unistic infection
Hep B, Hep C, HIV screening (immun­osu­pre­ssion)
 

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  • Published: 29th July, 2022

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