Show Menu
Cheatography
  1. Home >
  2. Education >

Drug acting on neuromuscular junction Cheat Sheet by

drug acting on neuromuscular junction

Classi­fic­ation Neurom­uscular blocking agent

Pre-ju­nct­ional blocker
Post-j­unc­tional blocker (Non-d­epo­lar­izing
Post-j­unc­tional blocker (Depol­arizing
Antich­oli­nes­terase (Anti-­ACHase) inhibitor
MOA:
1) Prevent Ach release
2) Inhibit Ach synthesis
MOA:
1) Non-de­pol­ari­zing: compete with Ach, inhibit nicotinic Rc
MOA:
Act like Ach, bind to nicotinic Rc
MOA:
Inhibit Anti-A­CHase breaking down Ach
Example:
Butolinum toxin
Aminog­lyc­oside
Example:
d-tubocurarine
Example:
Suxamethonium
Example:
Neostigmine
Edroponium
 
↓ muscle contra­ction
Phase 1: slight muscle contrx
Phase 2: desens­ati­zation, complete paralysis
↑ muscle contra­ction
 

Post-j­unc­tional blocker

NOTE:
- DeP: AntiAchase worsen effect
- NonDeP: AntiAchase reverse effect

List of drug
 

Metadata

  • Languages:
  • Published: 29th July, 2022

Comments

No comments yet. Add yours below!

Add a Comment

Your Comment

Please enter your name.

    Please enter your email address

      Please enter your Comment.

          Related Cheat Sheets

          Pharmacology Musculoskeletal Cheat Sheet
          NSAIDS Cheat Sheet

          More Cheat Sheets by aina

          Pharmacology Musculoskeletal Cheat Sheet
          Arrhytmia Cheat Sheet
          NSAIDS Cheat Sheet