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FOB exam 3 Cheat Sheet (DRAFT) by

Foundations of Biology EXAM 3

This is a draft cheat sheet. It is a work in progress and is not finished yet.

Phases of the cell cycle Mitosis

Prophase
Chromo­somes condense and spindle aparatus forms
Promet­aphase
Kineto­chores assembled at centro­mere, 2 opposite sides connected to microt­ubles
Metaphase
Lined up on imaginary metaphase plate. Polar microt­ubles extend from each spindle, overlap in middle, pole-pole connection
Anaphase
Cohesions are cleaved, daughters to opposite sides of cell. poles pulled apart
Telophase
Nuclear envelope reforms, chromo­somes begin to condence
Cytoki­nesis
Division of cytoplasm

Mitosis

Mitosis
When cells divide, two gentet­ically identical sister cells are their products
Uses
Somatic cells
 

DNA synthesis in Leading strand

Synthe­sized
Contin­ously
Begins with
RNA primer
After RNA primer
DNA polymerase

DNA synthesis in lagging strand

Synthe­sized
in fragments (Okazaki fragments)
Initiated by
RNA polymerase
RNA polymerase
builds primers
DNA polymerase
replicates DNA off of primers
RNA primer
popped out of gaps and replaced with DNA polymerase

Both leading and Lagging strands

Single stranded binding proteins (SSBs)
Keep stands from attatching back together
Ligase
Fills in gaps or breaks in phosph­odi­ester bonds of backbone
Helicase
Seperares, unwinds double stranded DNA
Topois­omerase
Helps with stress on wound DNA, ex. Gyrase