Descriptive Studies
ECOLOGIC STUDIES - |
involves making comparisons between variables where the unit of analysis is aggregated data on the population level rather than on the individual level |
CROSS-SECTION STUDIES |
all variables measured at a point in time |
CASE REPORT |
is a profile of a single individual; it includes qualitative descriptive research of the facts in chronological order |
CASE SERIES |
involves a small group of patients with a similar diagnosis |
RATIOS, PROPORTIONS, RATES
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Ratios, proportions, and rates are commonly used measures for describing dichotomous data. The general formula for a ratio, proportion, or rate is: X/Y x 10z |
RATES |
a type of frequency measure where the numerator involves nominal data that represent the presence or absence of a health-related state or event |
RATIOS |
the values of x and y are distinct, such that the values of x are not contained in y. The rate base for a ratio is 100 = 1 |
PROPORTIONS |
x is contained in y. A proportion is typically expressed as a percentage, such that the rate base is 102 = 100. |
Dichotomous data- Divided or dividing into two parts or classifications.
CALCULATION RATES
DEFINITIONS |
CALCULATIONS |
Incidence rate- is the number of new cases of a specified health-related state or event reported during a given time interval |
Incidence Rate= New cases occurring during a given time period/population at risk during the same time period multiplied by 10z |
Mortalilty Rate- is the total number of deaths reported during a given time |
Mortality Rate = Deaths occurring during a given time period/ Population from which deaths occurred Multiplied by 10z |
Person-Time Rate- When the denominator of the incidence rate is the sum of the time each person was observed |
Person Time rate= New cases occurring during an observationperiod/Time each person observed, totaled for all persons multiply by 10z |
Attack Rate- It involves a specific population during a limited time period, such as during a disease outbreak. It is also referred to as a cumulative incidence rate or risk |
Attack Rate=New cases occurring during a shirt time period/Population at risk at the beginning of the time period multiplied by 100 |
Secondary Attack Rate- the rate of new cases occurring among contacts of known cases. |
SAR= New cases among contacts of primary cases during a short time period/(Populations at beginning of time period)- (primary cases) multiplied by 100 |
Point Prevalence- he frequency of an existing health-related state or event during a time period. |
Point Prevalence= Existing cases of a disease or event at a point in time/total study population at a point in time multiplied by 100 |
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STRENGTHS AND WEAKNESSES
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DESCRIPTION |
STRENGTHS |
WEAKNESSESS |
Ecologic study |
Aggregate data involved (not for specific individuals |
Take advantage of preexisting data, can be used to evaluate programs, polices or regualtions implemted at the ecological level |
Susceptible to confounding exposure and disease or injury outcomes not measured on the same individuals |
Cross-section studies |
All variables measured at a point in time no distinction between potential risk factors and outcomes |
Control over study population and measurements. several associations between variables can be studied at the same time, short time period required |
Potential bias from low response rate, higher proportion of long-term survivors, does not yield incidence or relative risk |
Case study |
A snapshot description of a problem or situation for an individual or group |
in-depth description, provides clues to identify a new disease or adverse health effect resulting from exposure or experience |
Conclusion limited to the individual, group,and or context under study, cannot be used to establish a cause -effect relationship |
CRUDE RATES VS AGE-ADJUSTED RATE
Crude rate is calculated without any restrictions such as age. however, these rates are limited if the epidemiologist is trying to compare them between subgroups of the population or over time because of potential confounding influences, such as differences in the age distribution between groups. |
An age-adjusted rate is a weighted average of the age-specific rates.Rates based on data covering age intervals of 5 or 10 years are generally preferred because they are more stable than rates based on single-year age intervals. |
Indirect method of age adjustment- In situations in which age-specific rates are unstable because of small or missing numbers, age adjustment is still possible with the indirect method. |
standard morbidity/mortality ratio (SMR). |
Interpretation ■ SMR = 1: The health-related states or events observed were the same as expected from the age-specific rates in the standard population. ■ SMR > 1: More health-related states or events were observed than expected from the age-specific rates in the standard population. ■ SMR < 1: Fewer health-related states or events were observed than expected from the age-specific rates in the standard population. |
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4 TYPES OF DATA
Nominal |
unordered categories or classes (e.g., gender, race/ethnicity, marital status, occupation). |
Ordinal |
additional information provided by the order among categories (e.g., stage or grade of cancer). |
Dsicrete |
integers or counts that differ by fixed amounts, with no intermediate values possible (e.g., number of new cases of lung cancer reported in the United States in a given year, number of children, number of sick days taken in a month). |
Continous |
measurable quantities not restricted to taking on integer values (e.g., age, weight, temperature). |
TABLES, GRAPHS AND NUMERICAL MEASURES
The simplest table is the frequency distribution, which is a complete summary of the frequencies, or number of times each value appears. |
Epidemic Curve- is a histogram that shows the course of an epidemic by plotting the number of cases by time of onset. ■ A stem-and-leaf plot is a display that organizes data to show their distribution. |
A histogram shows a frequency distribution for discrete or continuous data. |
Bar charts are often used for graphically displaying a frequency distribution that involves nominal or ordinal data. |
Numerical Methods
Measures of central tendency refer to ways of designating the center of the data. The most common measures are the arithmetic mean, geometric mean, median, and mode |
Arithmetic and Geometric Mean |
Measures of dispersion, also called the spread or variability, are used to describe how much data values in a frequency distribution vary from each other and from the measures of central tendency. |
Numerical Methods
Measures of central tendency refer to ways of designating the center of the data. The most common measures are the arithmetic mean, geometric mean, median, and mode |
Arithmetic and Geometric Mean |
Measures of dispersion, also called the spread or variability, are used to describe how much data values in a frequency distribution vary from each other and from the measures of central tendency. |
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