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Medication Names
Prototye Med |
somatropin (Genotropin) |
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Nutropin |
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Humatrope |
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Serostim |
ACTION: Stimulates the release of insulin-like growth factor-1, abbreviated IGF-1, from the liver and other tissues.
Therapeutic Use
Growth hormone deficiencies, such as Turner’s syndrome |
Growth hormone deficiency in adults to increase lean muscle mass |
AIDS wasting syndrome |
Adverse
Hyperglycemia |
Fatality in PWS Clients |
Neutralizing antibodies |
Contraindications
Severe obesity |
Severe respiratory impairment |
Closed epiphyses in children |
Critical illness |
Interactions
Glucocorticoids and adrenocorticotropic hormone counteract growth-stimulating effects. |
Thyroid hormones, estrogens, and androgens promote epiphyseal clo- sure. |
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Nursing Interventions
Monitor blood glucose levels. |
Administration
Give IM or subcutaneously (preferable). |
Dosage is based on weight |
Given daily or several times a wee |
Very costly |
Pediatric Clients: Obtain baseline height, weight, thyroid function, and growth hormone levels and monitor monthly; yearly X-rays of long bones |
When reconstituting the drug, rotate the vial gently and do not shake it |
Inject subcutaneously into the abdomen and thighs and rotate sites. |
Discontinue treatment prior to epiphyseal closure in children. |
Client Instructions
Injection site should be rotated. |
Precautions
Diabetes mellitus |
Prader-Willi syndrome |
Hypothyroidism |
Chronic renal failure |
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