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Bisphosphonates - alendronate (Fosamax) Cheat Sheet by

used in the treatment of osteoporosis

Medication Name

Prototye Med
alendr­onate (Fosamax)
Other Meds
risedr­onate (Actonel)
 
Ibandr­onate (Boniva)
Drug Class: Bone Resorption Inhibitor
Action: decrease bone resorption by inhibiting activity of osteoc­lasts

Therap­eutic Use

Prevention and treatment of postme­nop­ausal osteop­orosis, glucoc­ort­icoid related osteop­orosis, age-re­lated osteop­orosis in men

Advese Effects

Esopha­gitis
Gastro­int­estinal distur­bances (nausea and vomiting, abdominal pain)
Muscle and joint pain
Eye pain and vision changes

Nursing Interv­entions

Give drug with 6–8 oz. of water.
For 30 minutes after taking drug, have clients:
Remain in upright position.
 
Avoid eating or drinking anything other than water.
 
Avoid giving calcium supplement or antacid.
Give analgesic for muscle and joint pain.
Monitor clients for changes in vision.

Admini­str­ation

Give drug 30 minutes before breakfast with a full glass of water.
Have client sit or stand for 30 minutes after admini­str­ation
Avoid giving calciu­m-c­ont­aining drugs/­sup­ple­ments within 30 minutes of admini­str­ation
 

Patient Education

Instruct clients to take drug with full glass of water.
Instruct clients to do the following for 30 minutes after taking drug:
Sit or stand up.
 
Avoid eating or drinking anything other than water.
 
Avoid taking calcium supplement or antacid.
Advise clients to take analgesic for muscle and joint pain and report pain that persists.
Instruct clients to report changes in swallowing or vision to provider

Contra­ind­ica­tions

Esophageal strict­ure­s/d­iso­rders or difficulty swallowing
Clients unable to sit up for 30 minutes after admini­str­ation
Renal insuff­iciency
Hypoca­lcemia

Precau­tions

Upper gastro­int­estinal disorders
Infection
Liver disease
Heart failure

Intera­ctions

Calcium supple­ments and dairy products decrease absorption when given within 30 minutes of each other
 

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