Treatment of urinary tract infections
Action: Agonist that acts on the bladder. Avtivates muscarinic reseptors in the detrusor muscle that lines the bladder causing it to contract.
Treatment of urinary retention
Adverse Drug Reactions
Excessive gastric acid and salivation, diarrhea, fecal incontinence
Monitor blood pressure, heart rate, and bowel elimination patterns
Monitor respiratory status.
Monitor for dizziness.
For in-patient use, have a bedpan or urinal readily available and assist with ambulation.
Take orally three to four times a day.
Take 1 hr before or 2 hr after meals.
Report dizziness, difficulty breathing, or fainting
Increase fluid intake to maintain hydration.
Do not engage in dangerous activities if dizziness occurs or tends to recur.
Sit or lie down if feeling dizzy.
Low cardiac output, Asthma, chronic obstructive pulmonary disease
Gastric ulcers, Intestinal obstruction, Recent intestinal surgery
Urinary tract obstruction or bladder wall weakness
History of syncope
Cholinesterase inhibitors worsen cholinergic effects and increase the risk of toxicity
Mecamylamine (Inversine) worsens abdominal symptoms and hypoten- sion.
Procainamide (Pronestyl), quinidine, atropine, and epinephrine interfere with therapeutic effects.