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patho unit8 Enviornmental& Nutritional disease Cheat Sheet by

For personal exam revision lol

Smog

- Smoke+ Fog
1. Reducing fog (Coal combus­tion, SOx)
2. Photoc­hemical oxidant smog (Incom­plete combus­tion)

Tobacco smoke

Major
Minor
Pregnancy
10x Higher prob of lung cancer
Cardio­vas­cular disease
impact on fetus weight

Malnut­rition

Marasmus
Kwashi­orkor
- Starving
- Protein deficiency
- Normal serum albumin level
- Hypoal­bum­inemia
- Loss of muscle
- General edema

Vit. A

Function
Deficiency
- Vision
- Night blindness
- Differ­ent­iation of epithelial cells
- Xeroph­tha­lamia
- Host resistance
- Pulmonary infections
- Metabolic effects on retinoids
- Stones
 
- Hyperk­era­tosis
 

Lead

Toxicity
l
Storage
1. Inhibit heme synthesis
l
Bone& Teeth >Blood >Soft tissue
2.2 Interfere brain develo­pme­nt& nerve transm­ission
l

Vit. D

Source
Deficiency
- UV light
1. Children: Rickets
- Dietary source
- Cartilage overgrowth
Metabolism
2. Adult: Osteom­alacia
1,25(OH)2D: Most active form
- Uncalc­ified bone
Functions
- Ca, P intestinal absorption
- PTH-de­pendent reabso­rption
- Steroid hormone

Vit. K

- Synthesis of clotting factor VII, IX, X
- Bleeding diathesis

Vit. C

- NOT synthe­sized
Scurvy
- Metabolism of collag­en& basic intrac­ellular matrix
- Bleeding tendency
 

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  • Published: 8th December, 2023

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