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Cheatography

Antibiotic Coverage Cheat Sheet (DRAFT) by

Various bugs based on location in the body and the drugs that cover them

This is a draft cheat sheet. It is a work in progress and is not finished yet.

Bacterial Infections Based on Bugs

When Prophy­laxis is Approp­riate

Prosthetic heart valve/­val­vular disease + dental­/oral procedures
- infective endoca­rditis
- GU/GI procedures
Rheumatic fever (recur­rence)
People in contact with mening­ococcal disease
Surgical
People at high risk/in contact with TB
People at high risk/in contact with HIV

Medically Important Microo­rga­nisms

G+/G- cocci
G+/G- bacilli
Anaerobes
Spiroc­hetes
Mycoplasma
Chlamydia
 

General AE of ABX

Vomiting
Severe watery diarrhea
Abdominal cramps
Allergic rxn

Antibiotic Spectra

Narrow Spectrum
Active against single or limited group of microo­rga­nisms
Extended Spectrum
Effective against G+ and some G-
Broad Spectrum
Effective against both G+ and G-

Static Vs. Cidal

Bacter­ios­tatics
inhibit growth without causing death

Sulfonamides (DNA synthesis), Chlora­mph­enicol (trans­cri­ption and transl­ation)

Relies on INTACT immune system to clear nongro­win­g/v­iable bacteria
Bacter­icidal
Kill bacteria

PCN (cell wall inhibitor)

Can be given to patients with COMPRO­MISED immunity
 

Empiric Treatment - Match the Bug to Location

G+ cocci
Skin
G- bacilli
Urethras
G+, G-, anaerobes
Large Intestine

Drug Distri­bution

 

Antibiotic Activity

Site of Action of ABX

Cell Wall Inhibitors
Fosfomycin
Cyclos­erine
Vanco
PCN
CPN
Monoba­ctams
Carbap­enems
Ethambutol
Pyrraz­inamide
Isoniazid
DNA Synthesis & Integrity Inhibitors
Sulfon­amides
Trimet­hoprim
Quinolones
Transc­ription & Transl­ation Inhibitors
Rifampin
AGs
Specti­nomycin
Tetrac­yclines
Macrolides
Chlora­mph­enicol
Strept­ogr­amins
Oxazol­idi­nones