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Immuno-stimulants & performance enhancers Cheat Sheet (DRAFT) by

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This is a draft cheat sheet. It is a work in progress and is not finished yet.

Summary:

Immuno­sti­mulants
Perfor­mance enhancers
Androg­raphis
Ginseng
Echinacea
Nigella
IS: prevent and treat viral/URT infections
PE: improve mental and physical functions

Ginseng

A.I:
Uses:
Ginsend abuse syndrome (GAS)
Ginsen­g/Herb intera­ctions
- Triter­penoid saponins (ginse­nosides or panaxo­sides)
- Balance blood glucose level
From chronic use of more than 3 g/day.
Ginseng + Caffeine= amplif­ication of stimulant caffeine.
- B vitamins, flavon­oids, carboh­ydrates
- Improves erectile dysfun­ction
A CNS excitation manifested by elevated BP, hyperg­lyc­emia, nervou­sness, insomnia, skin eruptions.
Results in nervou­sne­sess, insomnia, alertness.
 
- As an adaptogen, reduces physical & mental stress(from cold, heat, noise, high altitudes, etc) and is safe, non-toxic with broad uses for health.
- Classified as adaptogens
- Standa­rdized extract dose: 200-600 mg/day.
- Unlike stimul­ants, which have an increase then marked decrease with respect to average level perfor­mance, adaptogens have a gradual increase above average level of perfor­mance.

Androg­raphis "­Indian echina­cea­"

A.I.:
MOA:
Doses:
Safety:
Diterpenes (andro­gra­pholide & deoxya­ndr­ogr­aph­olide) Very bitter in taste.
- Anti-i­nfl­amm­ato­ry/­Ant­i-a­lle­rgy­/An­tip­latelet aggreg­ation.
- For comon cold ttt: 400 mg 3x/day.
- 3 months max use due to inhibitory effect on platelets aggreg­ation.
 
- Increases Ab activiy & macrop­hages phagoc­ytosis.
- For preven­tion: 200 mg once/day.
Caution with patients taking warfarin or other blood thinners "Drug-Herb intera­ction"
 
- Inhibits PAF "­pla­telet activating factor­"
 
- Avoid with immuno­sup­pre­ssive agents
- Known as "king of bitter­s".
- In tradit­ional Chinese medicine.

Echinacea "­Con­efl­owe­r"

A.I.:
Uses:
AE:
- Phenolic compounds: Caffeic acid deriv. (cynarin, chichoric acid & echina­coside)
Reduces severity and duration of a RT infection (acts within a few days/q­uickly).
Allergic reaction as rash and asthma
Echina­coside has activity comparable to broad-­spe­ctrum activity of penici­llin.
 
Caution with autoimmune diseases as AID and MS (no clinical evidence, only theore­tical).
- Alkyla­mides (echin­acein)
- High m.wgt polysa­cch­arides
- From fam. Astera­ceae.
- Improves overall immune response, so improved resistance to infect­ions.
- Improves blood circul­ation to remove toxins.
- Pharma­col­ogical effects appear to be from A.I combin­ation.
 

Nigella seeds "­black seeds"

A.I.:
- (Aromatic) Volatile oils: thymoq­uinone, P-cymene
- fixed oils: PUFA (fot ttt of CVD)