This is a draft cheat sheet. It is a work in progress and is not finished yet.
Commonly Prescribed For...
Myocardial Infarction |
Glaucoma |
Angina |
Migraine |
Hypertension |
Phaeochromocytoma |
CHF |
Anxiety Disorders |
Arrhythmia |
Hyperthyroidism |
Indications
Competitive Antagonist |
Beta-Adrenergic Blocking Agent |
Antihypertensive |
Mechanism Of Action
β-1 |
Located in heart & kidneys: Stimulation produces renin release, and induce positive chronotropic and inotropic effects on the heart, increase cardiac conduction, increase cardiac velocity, and increase cardiac automaticity. |
β-2 |
Located lungs, GI tract, liver, uterus, vascular smooth muscle, and skeletal muscle: When stimulated this site produces vasodilation, bronchodilation, uterine relaxation, smooth muscle relaxation, tremor in skeletal muscles, and increases glycogenolysis |
β-3 |
Located in fat cells: Stimulation induces lipolysis |
Blocks the binding sites on adrenergic beta receptors: These receptors belong to the SNS which control fight or flight response. Beta Blockers compete with adrenaline and noradrenaline (both sympathetic neurotransmitters) at the three beta receptor binding sites. |
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