MOAs
Ibuprofen |
1st Generation Non-Selective COX-1 Inhibitor |
Aspirin |
Nonselective, irriversible COX-1 Inhibitor |
Acetaminophen |
Centrally Acting |
Celecoxib |
2nd Generation COX-2 Inhibitor |
Prednisone |
Glucocorticoid |
Penecillin G (Penecillin) |
Inhibits cell wall synthesis by binding to PBPs |
Vancomycin (Misc.) |
Inhibits cell wall synthesis |
Gentamycin (Aminoglycoside) |
Inhibits protein synthesis |
Erythromycin (Macrolide) |
Inhibits protein synthesis |
Ciprofloxacin (Quinoles) |
Inhibits bacterial DNA enzymes |
Tetracycline (Tetracycline) |
Inhibits protein synthesis |
Cephalexin (Cephalosporin) |
Inhibits cell wall synthesis by binding to PBPs |
Sulfamethoxazole/Trimethoprim (Sulfonamide) |
Inhibits folic acid synthesis |
Morphine |
Bind to opioid receptors in the CNS which inhibits ascending pain pathways, altering perception of and response to pain; CNS Depression |
Hydromorphone |
Bind to opioid receptors in the CNS which inhibits ascending pain pathways, altering perception of and response to pain; CNS Depression |
Fentanyl |
Bind to opioid receptors in the CNS which inhibits ascending pain pathways, altering perception of and response to pain; CNS Depression |
Codeine |
Bind with opiate receptors in the CNS which inhibits ascending pain pathways, altering perception of and response to pain |
Oxycodone |
Bind with opiate receptors in the CNS which inhibits ascending pain pathways, altering perception of and response to pain |
Naloxone |
Opioid Antagonist |
Tramadol |
Inhibit serotonin/norepinephrine reuptake |
Acetaminophen |
Centrally Acting |
|
|
ADR
Ibuprofen |
Gastric ulcers, GI upset/bleeding, BB: CVA, MI, |
Aspirin |
GI upset, tinnitus, reyes syndrome, salt/water retention |
Acetaminophen |
Hepatotoxicity |
Celecoxib |
MI, CVA, ulcers, GI bleeding, impaired renal function |
Prednisone |
sudden weight gain (Cushing's Syndrome), sepsis, hyperglycemia, osteoporosis, cataracts, addisons disease |
Penecillin G (Penecillin) |
Hypersensitivity, GI upset (nausea, vomiting, diarrhea), superinfections, anaphalaxis, caution for kidney function |
Vancomycin (Misc.) |
Nephrotoxicity, Ototoxicity, Red Man Syndrome, Thrombophebitis |
Gentamycin (Aminoglycoside) |
Nephrotoxicity, ototoxicity, nausea/vomiting/diarrhea, heart palpitations, hypersensitivity |
Erythromycin (Macrolide) |
QT Prolongation, sudden cardiac death, superinfection, GI upset, CLOG |
Ciprofloxacin (Quinole) |
QT Prolongation, tendinitis, tendon rupture, nausea, vomiting, diarrhea |
Tetracycline (Tetracyclines) |
Teeth discoloration, photosensitivity, superinfection, weakening of skeletal structure, GI upset |
Cephalexin (Cephalosporins) |
Hypersensiticity, bleeding, thrombophlebitis, hemolytic anemia, superinfections (C. Diff) |
Sulfamethoxazole/Trimethoprim (Sulfonamide) |
Steven Johnson Syndrome, hypersensitivity, hyperkalemia, hemolytic anemia, kernicterus, renal damage |
Morphine |
Respiratory Depression, Addiction, misuse, abuse, orthostatic hypotension, sedation, neurotoxicity, constipation, urinary retention, emesis, cough suppression, elevation of intracranial pressure |
Hydromorphone |
Respiratory Depression, Addiction, misuse, abuse, orthostatic hypotension, sedation, neurotoxicity, constipation, urinary retention, emesis, cough suppression, elevation of intracranial pressure |
Fentanyl |
Respiratory Depression, Addiction, misuse, abuse, orthostatic hypotension, sedation, neurotoxicity, constipation, urinary retention, emesis, cough suppression, elevation of intracranial pressure |
Codeine (same but less severe) |
Respiratory Depression, Addiction, misuse, abuse, orthostatic hypotension, sedation, neurotoxicity, constipation, urinary retention, emesis, cough suppression, elevation of intracranial pressure |
Oxycodone (same but less severe |
Respiratory Depression, Addiction, misuse, abuse, orthostatic hypotension, sedation, neurotoxicity, constipation, urinary retention, emesis, cough suppression, elevation of intracranial pressure |
Naloxone (Narcan) |
aggression, withdrawal |
Tramadol |
suicide, depression |
Acetaminophen |
hepatotoxicity |
|
|
Nursing Implications
Ibuprofen |
Aspirin |
Acetaminophen |
Celecoxib |
Prednisone |
Penecillin G (Penecillin) |
Vancomycin (Misc.) |
Gentamycin (Aminoglycoside) |
Erythromycin (Macrolide |
Ciprofloxacin (Quinole) |
Tetracycline (Tetracyclines |
Cephalexin (Cephalosporin) |
Sulfamethoxazole/Trimethoprim (Sulfonamide |
Morphine |
Hydromorphone |
Fentanyl |
Codeine |
Oxycodone |
Naloxone |
Tramadol |
Acetaminophen |
Nursing Implications
Ibuprofen |
Aspirin |
Acetaminophen |
Celecoxib |
Prednisone |
Penecillin G (Penecillin) |
Vancomycin (Misc.) |
Gentamycin (Aminoglycoside) |
Erythromycin (Macrolide |
Ciprofloxacin (Quinole) |
Tetracycline (Tetracyclines |
Cephalexin (Cephalosporin) |
Sulfamethoxazole/Trimethoprim (Sulfonamide |
Morphine |
Hydromorphone |
Fentanyl |
Codeine |
Oxycodone |
Naloxone |
Tramadol |
Acetaminophen |
Nursing Implications
Ibuprofen |
. |
Aspirin |
. |
Acetaminophen |
. |
Celecoxib |
. |
Prednisone |
. |
Penecillin G (Penecillin) |
. |
Vancomycin (Misc.) |
. |
Gentamycin (Aminoglycoside) |
. |
Erythromycin (Macrolide |
. |
Ciprofloxacin (Quinole) |
. |
Tetracycline (Tetracyclines |
. |
Cephalexin (Cephalosporin) |
. |
Sulfamethoxazole/Trimethoprim (Sulfonamide |
. |
Morphine |
. |
Hydromorphone |
. |
Fentanyl |
. |
Codeine |
. |
Oxycodone |
. |
Naloxone |
. |
Tramadol |
. |
Acetaminophen |
. |
| |
. |
Nursing Implications
Ibuprofen |
. |
Aspirin |
. |
Acetaminophen |
. |
Celecoxib |
. |
Prednisone |
. |
Penecillin G (Penecillin) |
. |
Vancomycin (Misc.) |
. |
Gentamycin (Aminoglycoside) |
. |
Erythromycin (Macrolide |
. |
Ciprofloxacin (Quinole) |
. |
Tetracycline (Tetracyclines |
. |
Cephalexin (Cephalosporin) |
. |
Sulfamethoxazole/Trimethoprim (Sulfonamide |
. |
Morphine |
. |
Hydromorphone |
. |
Fentanyl |
. |
Codeine |
. |
Oxycodone |
. |
Naloxone |
. |
Tramadol |
. |
Acetaminophen |
. |
Nursing Implications
Ibuprofen |
. |
Aspirin |
. |
Acetaminophen |
. |
Celecoxib |
. |
Prednisone |
. |
Penecillin G (Penecillin) |
. |
Vancomycin (Misc.) |
. |
Gentamycin (Aminoglycoside) |
. |
Erythromycin (Macrolide |
. |
Ciprofloxacin (Quinole) |
. |
Tetracycline (Tetracyclines |
. |
Cephalexin (Cephalosporin) |
. |
Sulfamethoxazole/Trimethoprim (Sulfonamide |
. |
Morphine |
. |
Hydromorphone |
. |
Fentanyl |
. |
Codeine |
. |
Oxycodone |
. |
Naloxone |
. |
Tramadol |
. |
Acetaminophen |
. |
Nursing Implications
Ibuprofen |
. |
Aspirin |
. |
Acetaminophen |
. |
Celecoxib |
. |
Prednisone |
. |
Penecillin G (Penecillin) |
. |
Vancomycin (Misc.) |
. |
Gentamycin (Aminoglycoside) |
. |
Erythromycin (Macrolide |
. |
Ciprofloxacin (Quinole) |
. |
Tetracycline (Tetracyclines |
. |
Cephalexin (Cephalosporin) |
. |
Sulfamethoxazole/Trimethoprim (Sulfonamide |
. |
Morphine |
. |
Hydromorphone |
. |
Fentanyl |
. |
Codeine |
. |
Oxycodone |
. |
Naloxone |
. |
Tramadol |
. |
Acetaminophen |
. |
Nursing Implications
Ibuprofen |
. |
Aspirin |
. |
Acetaminophen |
. |
Celecoxib |
. |
Prednisone |
. |
Penecillin G (Penecillin) |
. |
Vancomycin (Misc.) |
. |
Gentamycin (Aminoglycoside) |
. |
Erythromycin (Macrolide |
. |
Ciprofloxacin (Quinole) |
. |
Tetracycline (Tetracyclines |
. |
Cephalexin (Cephalosporin) |
. |
Sulfamethoxazole/Trimethoprim (Sulfonamide |
. |
Morphine |
. |
Hydromorphone |
. |
Fentanyl |
. |
Codeine |
. |
Oxycodone |
. |
Naloxone |
. |
Tramadol |
. |
Acetaminophen |
. |
Nursing Implications
Ibuprofen |
. |
Aspirin |
. |
Acetaminophen |
. |
Celecoxib |
. |
Prednisone |
. |
Penecillin G (Penecillin) |
. |
Vancomycin (Misc.) |
. |
Gentamycin (Aminoglycoside) |
. |
Erythromycin (Macrolide |
. |
Ciprofloxacin (Quinole) |
. |
Tetracycline (Tetracyclines |
. |
Cephalexin (Cephalosporin) |
. |
Sulfamethoxazole/Trimethoprim (Sulfonamide |
. |
Morphine |
. |
Hydromorphone |
. |
Fentanyl |
. |
Codeine |
. |
Oxycodone |
. |
Naloxone |
. |
Tramadol |
. |
Acetaminophen |
. |
Nursing Implications
Ibuprofen |
. |
Aspirin |
. |
Acetaminophen |
. |
Celecoxib |
. |
Prednisone |
. |
Penecillin G (Penecillin) |
. |
Vancomycin (Misc.) |
. |
Gentamycin (Aminoglycoside) |
. |
Erythromycin (Macrolide |
. |
Ciprofloxacin (Quinole) |
. |
Tetracycline (Tetracyclines |
. |
Cephalexin (Cephalosporin) |
. |
Sulfamethoxazole/Trimethoprim (Sulfonamide |
. |
Morphine |
. |
Hydromorphone |
. |
Fentanyl |
. |
Codeine |
. |
Oxycodone |
. |
Naloxone |
. |
Tramadol |
. |
Acetaminophen |
. |
|
