Tetracyclines – impairs the bactericidal effects of B-lactams
Penicillin G procaine and Penicillin G benzathine (i.m.) - formulated to delay absorption, resulting in prolonged blood and tissue concentrations.
Indications: MSSA, MSSE, Bone, joint, urinary tract, skin, endocarditis, meningitis
Indications: Respiratory infections, UTI, skin, bacterial meningitis, septicemia, endocarditis, GI infections (typhoid fever, dysentery)
Indications: Folliculitis, osteomyelitis, endocarditis, UTI, respiratory tract, wounds, bacteremia, CNS
Formulation of ticarcillin and piperacillin with β-lactamase inhibitors (formulation with clavulanic acid or tazobactum, respectively), extends the antimicrobial spectrum to include penicillinase-producing organisms