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L2 Overview of innate immunity Cheat Sheet (DRAFT) by

L2 Overview of innate immunity

This is a draft cheat sheet. It is a work in progress and is not finished yet.

3 Essential functions

1) Initial response to microbes
2) Eliminate damaged cells and initiate the process of tissue repair
3) Stimulate adaptive immune response
2 types of responses
 
1) Inflam­mation
 
2) Anti-viral defence
 

Components of innate immunity

1.Anat­omical barrier:
- Physical barriers - Chemical barriers
2.Cell:
- Phagocytic cells - Dendritic cell - NK cells, ILC
3.Soluble protein:
- Complement - Cytokines, chemokines - Antimi­crobial substances
 

Anatomical barriers - Physical

Anatomical barriers - Physical

 

Cellular response

Phagocytic cells: - Macrop­hage, neutrophil
“Phago­cyt­osis” 1) Dendritic cell -> activate adaptive immune response
The immune system 1) Detect­s/s­enses the presence of a pathogen 2) Mounts a response