This is a draft cheat sheet. It is a work in progress and is not finished yet.
Hypertensive Disorders of Pregnancy
• 5-10% of pregnancies |
• ↑ maternal-fetal morbidity & mortality worldwide |
• Risk of injury to woman and fetus related to CNS irritability |
• seizures • placental abruption • IUGR |
pre-eclampsia
• after 20 weeks • BP > 140/90 x 2
• with or without proteinuria (PCR > 0.3) |
severe features: • thrombocytopenia • liver failure (LFTs 2x normal)
• new renal insufficiency (serum creatinine > 1.1 mg/dL)
• pulmonary edema • new onset cerebral or visual disturbance |
pathophysiology of preeclampsia
inadequate vascular remodeling →⬇ placental perfusion & hypoxia
→ endothelial cell dysfunction → vasospasm & ↓ tissue perfusion |
•HTN •IUGR •h/a •hyperreflexia •seizures •scotoma •epigastric pain |
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chronic hypertension in pregnancy
before 20 weeks (use of anti-hypertensive meds before pregnancy) |
persists > 12 weeks postpartum (PP) |
BP >140/90 |
gestational hypertension in pregnancy
after 20 weeks |
BP > 140/90 |
no proteinuria |
if persists > 12 weeks PP -> CHTN |
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