ACUTE DISEASES OF THE NEWBORN
- high-risk neonate regardless of Gestational Age
- begins 23wks - 28 days post birth |
CLASSIFICATIONS OF HIGH RISK NB
According to Size
- Low Birth Weight LBW (<2.5kg)
- Very Low Birth Weight VLBW (<1.5kg)
- Extremely Low Birth Weight ELBW (<1kg)
- Appropriate for Gestational Age AGA (10%-90%)
- Small for Gestational Age SGA (<10%)
- Large for Gestational Age LGA (>90%)
- Intrauterine Growth Restriction IUGR
>Risk Factors:
- Hereditary
- Placental Insufficiency
- Maternal Disease
According to Gestational Age (regardless of BW)
- Late Preterm (34-36wks AOG)
- Preterm (<37wks AOG)
- Full term (38-42wks AOG)
- Post term (>42wks AOG)
According to Mortality
- Live Birth
- Fetal Death
= death before 20wks
- Neonatal Death
= death within first 27wks of extrauterine life
- Perinatal Mortality
= total # of fetal & neonatal death/1000 live births
- Postnatal Death
= death 28 days - 1y/o |
Intrauterine Growth Curve
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ASSESSMENT OF HIGH-RISK NB
1. Physical Assessment
- General Assessment
> BW
> Anthropometric Measurements
> Deformities
> Signs of distress (poor color, mottling, hypotonia)
2. Respiratory Assessment
- Chest Shape (barrel/concave)
- Describe use of accessory muscles
- Determine RR; O2 Sat
- Auscultation
3. Cardiovascular Assessment
- HR and rhythm
- Auscultation
- Determine Point of Maximal Impulse (PMI)
- Color
> mucous membranes, lips, BP, perfusion
4. Genitourinary Assessment
- Genitalia and abnormalities
- Describe urine
> amount, pH, specific gravity
5. Gastrointestinal Assessment
- Presence of abdominal distention, regurgitation
- Stool assessment
> amount, color, consistency
6. Neurologic-Musculoskeletal Assessment
- Movements, Level of Activity with stimulation
- Changes in Head Circumference
7. Temperature
- Determine axillary temperature |
HIGH-RISK CONDITIONS RT DYSMATURITY
1. Preterm Infants
- Cause:
> idiopathic
- Risk Factors:
> low socio-economic status
> multigravida
> gestational HTN
- Characteristics:
> very small and thin; little SQ fat
> proportionally large head
> bright pink, shiny, smooth skin
> abundant fine lanugo
> ear cartilage soft and pliable
> male NB = few scrotal rugae; cryptochordism
> female NB = labia minora & clitoris prominent
2. Post-term Infants
- Cause:
> idiopathic
- Characteristics:
> absent lanugo
> abundant scalp hair; long fingernails
> cracked skin/parchment-like/desquamation
> depleted SQ fat
> little vernix caseosa |
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PROBLEMS RT GESTATIONAL WEIGHT
SGA RT Intrauterine Growth Restriction (IUGR)
- Cause:
> poor nutrition
> adolescent pregnancy
> placental anomaly
> maternal systemic disease (HTN, DM)
- Diagnostic Evaluation
> fundal height < expected
> UTZ = size; placental grading; amniotic fluid
> biophysical profile
> non-stress test (NST)
-Fetal Implications
> poor skin turgor
> large head, small body
> small liver
> skull sutures widely separated
> Hct level
> polycythemia ( RBC)
> hypoglycemia (<45mg/dL) |
LGA (Macrosomia)
- appears healthy, but will soon reveal underdevelopment
- Causes:
> gestational DM (GDM)
> multiparity
> Beckwith Syndrome (overgrowth+macroglossia)
> congenital anomalies (omphalocele)
- Diagnostic Evaluation
> UTZ
> NST
> amniocentesis
- Fetal Implications
> immature reflexes
> extensive bruising/birth injury/Erb-Duchenne
> caput succedaneum; cephalhematoma
> hyperbilirubinemia
> polycythemia vera
> cyanosis
> insulin (up to 24hrs post birth=hypoglycemia) |
MANAGEMENT OF HIGH-RISK NEWBORN
NEWBORN PRIORITIES
1. Initiating/Maintaining Respiration
- most deaths occur within 48hrs
- ineffective respiration = cerebral hypoxia
> Management:
- O2 administartion
- appropriate positioning to open airway
- resuscitation+ventilation
2. Establish Extrauterine Circulation
> Management:
- closed-chest massage (1-2cm, 100x/min)
- lung ventilation (30x/min)
- monitor pulse oximeter
- 0.1-0.3mL/kg Ephinephrine may be sprayed on ET tube
- transfer to NICU
3. Maintain Fluid Balance
> Management: (after initial resuscitation)
- Hypoglycemia (D10W IVF)
- Hypotension (vasopressor Dopamine)
- Hypovolemia (NSS/RL IVF)
- Dehydration (RL/D5W IVF)
4. Maintaining Thermoneutrality
> Management:
- thorough drying
- skin-skin contact
- neutral thermal environment
5. Establishing Adequate Nutritional Intake
> Management:
- parenteral/enteral nutrition
- breastfeeding
6. Establishing Waste Elimination
- Immature infants void within 24hrs
- stool passage may be later than term infants
7. Protection from Infection
> Prevention:
- handwashing and PPE use
- standard precautions
- physical isolation
8. Skin Care
- skin sensitivity & fragility
> Management:
- Zinc Oxide-based tape is used
- avoid use of solvents
9. Establishing Mother-Infant Bonding
- parents kept informed
- spend time with NB |
*2. (1:3 = Lung ventilation:Cardiac massage)
*3. Monitor UO (if UO=<2mL/kg/hr = inadequate fluid intake)
*4. 3 Main Methods for Neutral Thermal Environment: Incubator, Radiant panel, Bassinet
*5. If gavage fed, provide oral stimulation to develop effective sucking reflex
ACUTE CONDITIONS OF NEONATES
Respiratory Distress Syndrome (RDS)
- Hyaline Membrane Disease
- surfactant deficiency
- Types:
> Structural
- lungs are underdeveloped
- respiratory muscle prone to fatigue
> Functional
- deficient surfactant
- Risk Factors:
> Multifetal pregnancy
> GDM
> CS Delivery
> Cold stress
> Asphyxia
> Hx of RDS
- RDS of Non-Pulmonary Origin Risk Factors:
> Sepsis
> Cardiac Defect
> Hypoglycemia
> Metabolic Acidosis
> Drugs
- Clinical Manifestations:
> tachypnea (>60cpm)
> retractions; nasal flaring
> inspiratory crackles
> circumoral and central cyanosis
- Laboratory Diagnoses:
> Glucometry (tests hypoglycemia)
> ABG (tests acidosis, hypoxia, hypercapnia)
> CXR
- diffuse granular pattern = alveolar atelectasis
- dark streaks = dilated, air-filled bronchioles
-Treatment:
> ventilation and oxygenation with Continuous Positive Airway Pressure (CPAP)
> maintain acid-base balance
> neutral thermal environment
> maintain hydration and electrolytes
> avoid nipple and gavage feedings
> administer exogenous surfactants
- Nursing Responsibilities:
> collect and monitor ABG
> O2 monitoring
> assess tolerance on procedure/drug |
* Surfactants produced at 24wks AOG, matures at 36wks
* Surfactant Complications: pulmonary hemorrhage; mucus plugging
Meconium Aspiration Syndrome
Meconium
- sticky and tarlike; present at bowel 10wks AOG
- accumulates at 16wks AOG
Meconium Aspiration
- occurs inside utero/at first breath at birth
- occurs when the vagus reflex is stimulated due to hypoxia releasing meconium to amniotic fluid
- NB born at breech position
- Pathophysiology:
> hypoxiameconium passingaspirationobstructionatelectasisrespiratory failure
- Clinical Manifestations:
> tachypnea; retractions; expiratory grunting; nasal flaring
> cyanosis/pallor
> barrel chest (from hyperinflation)
> hypoglycemia; hypocalcemia
- Diagnostic Evaluation:
> laryngoscopy
> CXR
- Management:
> tracheal suctioning
> intubation (in severe cases)
> surfactant administration
> Echocardiography (diagnose shunting)
> chest physiotherapy |
Apnea of Prematurity (AOP)
Apnea
- cessation of respiration that lasts >20secs, accompanied by bradypnea and cyanosis
Types:
1. Central Apnea
- absent function of diaphragmatic and other respiratory muscles
- CNS does not transmit signals to respiratory muscles
2. Obstructive Apnea
- airflow stops due to obstruction
3. Mixed Apnea
- central + obstructive
- most common on premature infants
- Causes:
> prematurity (weak thorax muscles)
> airway obstruction
> anemia; polycythemia vera
> hypoglycemia; hypocalcemia
> sepsis; meningitis; seizures
- Management:
> gentle tactile stimulation
> Caffeine Citrate PO/Parenteral (CNS Stimulant)
> monitor weight and UO (Caffeine citrate = diuretic)
> nasal CPAP & nasal intermittent positive pressure ventilation
> neutral thermal environment
- Nursing Responsibilities:
> routine observation (RR & HR)
> gentle tactile stimulation, if it fails, raise chin to open airway
> careful burping = reduces apnea
> never take rectal temperature |
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