Cheatography
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histology unit histology unit histology unit
This is a draft cheat sheet. It is a work in progress and is not finished yet.
Histology
Histology |
the study of tissue |
Tissue |
a group structurally and functionally related cells and their external environment that together perform common functions |
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tissues share 2 basic components: all tissues consist of discrete population of cells that are related in structure and function |
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all tissues have a surrounding material called extracellular matrix (ECM) |
Types of Tissues |
are defined by the kind and number of cells, the amount and composition of ECM and their specific functions |
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Epithelial tissues |
•tightly packed sheets |
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•no visible ECM |
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•cover and line all body surfaces and cavities |
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•forms secretory glands |
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Connective Tissues |
•connect all the other tissues in the body to one another |
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•ECM is a prominent feature for most connective tissues types with cells scattered throughout |
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•bind, support, protect, and allow for transportation of substances |
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•fill internal spaces |
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•provide structural support and energy |
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Muscle Tissue |
•contracts to produce movement and force |
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•skeletal muscle, cardiac muscle, and smooth muscle |
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little ECM between cells |
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Nervous Tissue |
consist of cells capable of generating, sending, receiving messages, and cells that support this activity all within a unique ECM |
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conduct electrical impulses |
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carries information |
Cell Junctions
Cell Junctions |
another way cells bind to one another where neighboring cell's plasma membranes are linked by integral proteins |
3 Major Types of Cell Junctions |
tight junctions ( occluding junctions ) |
hold cells closely together such that the space between is impermeable to the movement of macromolecules |
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desmosomes |
allow for materials in the ECF to pass through the space between cells |
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gap junctions |
small pores formed by protein channels between adjacent cells that allow small substances to flow freely between each cells cytoplasm |
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The Extracellular Matrix (ECM)
Extracellular matrix (ECM) |
composed of substances in a liquid, thick gel, or solid that surround the cells of a tissues |
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2 Components |
Ground Substance |
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Protein Fibers |
ECM Functions |
provides the tissue with strength to resist tensile (stretching) and compressive forces |
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directs cells to their proper positions within a tissue and holds those cells in place |
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regulates the development, mitotic activity, and survival of cells in a tissue |
Ground Substance |
Makes up most of ECM and consists of extracellular fluid (ECF) and their components: water, nutrients, and ions |
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also found: three families of macromolecules, glycosamingoglycans (GAGs), proteoglycans, and cell-adhesion molecules (CAMs) |
Protein Fibers |
long molecules composed of multiple fibrous subunits with a ropelike structure with enormous tensile strength |
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embedded within the ground substance |
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3 Types of Protein Fibers |
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Collagen Fibers |
composed of multiple repeating subunits that form a white fibrous protein that is resistant to tension ( pulling and stretching forces) and pressure |
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Elastic Fibers |
composed of the protein elastin surrounded by glycoproteins |
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has the property of extensibility that allows the fiber to stretch up to one and a half times its resting length without breaking |
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give elasticity |
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Reticular Fibers |
a thin short collagen fiber, form a meshwork that support the cells and ground substance of many tissues |
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form web-like structure in organs like the spleen that help trap foreign cells |
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The Extracellular Matrix (ECM)
Ground Substance and Protein Fibers
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