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AS Level - Transport in Mammals Cheat Sheet (DRAFT) by

Transport in Mammals - AL 9700 CAIE Biology

This is a draft cheat sheet. It is a work in progress and is not finished yet.

Closed Double Circul­ation

Blood is enclosed within capill­aries.
Blood travels through the heart twice in one complete circuit.
Double Circul­ation maintains a high blood pressure.

Types of Circul­ations

Pulmonary Circul­ation: Right ventricle pumps blood to the lungs.
Systemic Circul­ation: Left ventricle pumps blood to all body tissues.

Left Ventricle >> Right Ventricle

LV has a thicker wall than RV as LV pumps blood to all body tissues (syste­mic), so to generate more pressure to overcome high resist­ance.

Blood Capill­aries

The capill­aries

Capill­aries have lumens with a diameter of 7 μm --> just big enough for a RBC to squeeze through.
Capillary wall is one cell thick --> Less diffusion distance
Capill­aries have high surface area to volume ratio.
Capill­aries are very narrow --> to bring the RBCs very close to the cells.
Capill­aries have gaps in between the endoth­elial cells --> allow components of blood plasma to leak out, forming the tissue fluid.
 

The Arteries

Arteries further away from the heart have fewer elastic fibers in the tunica media, but they have more muscle fibers.
Arterioles have a greater proportion of smooth muscle.

The Veins

Wide lumen --> less resistance to blood flow.
Blood flows through veins by the contra­ction of skeletal muscles which squeeze inwards on the nearby veins, thus increasing the pressure inside them.

Valves

Valves prevent the backflow of blood.
Valves are held in place by tendons that are attached to papillary muscles.
Papillary muscles contract during ventri­cular systole to hold the AV valves closed and prevent the AV valves from flipping inside out.

EF, SM & CF

Elastic Fibers
Stretch during systole to expand­/dilate the BV, to accomm­odate the high pressure.
Recoil during diastole so the BV recoils back/c­ons­tricts to its original size, pushing the blood forward.
Smooth Muscle
Relax to widen/­dilate the BV, increasing the blood flow to tissues.
Contract to narrow­/co­nstrict the BV, reducing the bl0od flow to tissues.
They help to control the blood volume flowing into a tissue at different times.
Collagen Fibers
Help in withst­anding the high blood pressure.
BV = Blood Vessels --> Artery­/Vein.
 

Cardiac Cycle

Definition
It is the sequence of events that make up one heartbeat.
1. Atrial Systole (0.1s)
The atria contract, generating a pressure that forces blood into the relaxed ventricles through the open AV valves, while SL valves remain closed (to prevent backflow of blood into veins).
2. Ventri­cular Systole (0.3s)
The atria relax and the ventricles contract, generating a larger pressure that forces the blood to close the AV valves (to prevent backflow of blood into atria) and to open the SL valves (to allow blood flow into the arteries).
3. Diastole (0.4s)
The atria remain relaxed and the ventricles relax, so pressure in ventricles decreases.
When the ventri­cular pressure becomes lower than the arterial pressure and atrial pressure, SL valves close and AV valves open.
The heart beats around 75 times per minute.
Each cycle takes 0.8 seconds.

Cardiac Cycle Graph

Control of Heartbeat

1. SAN acts as a pacemaker,
sending out waves of excita­tion,
and causing the atria to contract.
2. Waves of excitation enters the AVN
which delay the impulse for a fraction of a second (0.1s).
3. This delay ensures that the atria and ventricles do not contract at the same time,
as the delay gives the atria enough time to fully empty their blood into the ventri­cles.
4. Waves of excitation pass down the Parkyne tissue down the septum,
causing the ventricles to contract from bottom upwards.
The cardiac muscle is myogenic --> it sponta­neously contracts on its own without the need for nerve impulses to initiate the contra­ction.