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Cheatography

Pleural Disease Cheat Sheet (DRAFT) by

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This is a draft cheat sheet. It is a work in progress and is not finished yet.

What are the pleura

Two layers of tissue surrou­nding lungs
• Visceral pleura – attached to lung.
• Parietal pleura – attached to chest wall
between layers
Pleural space/­cavity
Pleural lined by
mesoth­elial cells
Secrete
small amount pleural fluid for lubric­ation

Pneumo­thorax

Defenition
Air in pleural space
Two types to know about
• Sponta­neous
• Tension

Sponta­neous PTX

Primary
●Rupture of subpleural bleb
●Common in tall, thin young males
Secondary
●Older patients with underlying pulmonary disease
● COPD
Manife­station
◇ sudden onset dyspnea
◇Sometimes pleuritic chest pain(when you take a deep breath)
Diagnosis
CXR
 

Pneumo­thorax

Pneumo­thorax treatment

100% oxygen
◇Displaces nitrogen from capillary blood
◇↑gradient for nitrogen reabso­rption from pleural space
Chest tube
Larger pneumo­tho­races (>15% lung volume)

Tension PTX

Usually from trauma
Air enters pleural space but cannot leave
Medical emergency
Emergent thorac­ent­esi­s/chest tube placement
Trachea deviates AWAY from affected side
 

Pleural effusion

Accumu­lation of fluid in pleural effusion

Etiologies of pleural effusion

Transu­dative
Exudative
Lymphatic

Transu­dative effusion

Defenition
Something driving fluid into pleural space
Most common cause
CHF (high pressure)
Other causes
●Nephrotic syndrome
(low protein)
● Cirrhosis
(low albumin)
Treatment
Underlying cause (no driange)

Exudative effusion

Defenition
Fluid leaking into pleural space
•High vascular permea­bility
Many causes
◇ malignancy
◇ pneumonia
◇ More protein in pleural fluid vs. transu­dative
Treatment
Usually requires drainage

Transudate vs. Exudate

Thorac­entesis
to obtain fluid sample
Test for
protein, LDH
Light’s Criteria – Exudate if:
• Pleural protei­n/serum protein greater than 0.5
Pleural LDH/serum LDH greater than 0.6
Pleural LDH greater than 2/3 upper limits normal LDH

Lymphatic Effusi­ons­“Ch­ylo­thorax”

• Lymphatic fluid effusion
• From thoracic duct obstruction/injury
• Malignancy most common cause
• Trauma (usually surgical)
• Milky-­app­earing fluid
• Very high triglycerides
◇TG usually > 110 mg/dL

Other Effusions

Hemothorax
High Hct in fluid
Empyema
Infected pleural fluid
Pus, putrid odor, positive culture
Malignant effusion
Positive cytology

Mesoth­elioma

Defenition
Pleural tumor
only known risk factor
Asbestos
--->Decades after exposure
Imaging
Pleural thickening and pleural effusion
Slow onset symptoms
dyspnea, cough, chest pain
Poor prognosis
•Median survival 4 to 13 months untreated
• 6 to 18 months treated with chemo
Asbestos For those who work in shipyards