This is a draft cheat sheet. It is a work in progress and is not finished yet.
1. Proton Transfer
2. Carbocation Formation
3. Ion Attacks Carbocation
Favors 3rd and 2nd degree carbocations
Step 2 is RDS
- Cleavage of bond between C and leaving group
- Formation of bond between C and nucleophile
Favors methyl and 1st degree carbocations
Configuration is inverted
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1. Protonation of alcohol
2. Dissociation to carbocation and water
3. Deprotonation of cation
Favors 3rd degree carbocation
Often requires shifts
Dehydration of OH
- Strong base takes proton
- Loss of halide
Can be used by any degree of alcohol w/ strong base
Favors third degree
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