Major Functions
        
                        
                                                                                    
                                                                                             Gas exchange  | 
                                                                                 
                                                                                            
                                                                                             Blood pH regulation  | 
                                                                                 
                                                                                            
                                                                                             Voice production  | 
                                                                                 
                                                                                            
                                                                                             Olfaction  | 
                                                                                 
                                                                                            
                                                                                             Protection against airborne diseases  | 
                                                                                 
                                                                         
                             
    
    
    
            Associated Cells/Structures
        
                        
                                                                                    
                                                                                             Cilia  | 
                                                                                 
                                                                                            
                                                                                             Hair-like  | 
                                                                                 
                                                                                            
                                                                                             Traps and wafts out dirt, pathogens etc.  | 
                                                                                 
                                                                                            
                                                                                            |   | 
                                                                                 
                                                                                            
                                                                                            Goblet Cells: Makes mucous  | 
                                                                                 
                                                                                            
                                                                                            |   | 
                                                                                 
                                                                                            
                                                                                             Mucous Properties  | 
                                                                                 
                                                                                            
                                                                                             Sticky for trapping  | 
                                                                                 
                                                                                            
                                                                                             Has lots of H₂O for air humidifying  | 
                                                                                 
                                                                         
                             
    
    
            Age-Related Changes
        
                        
                                                                                    
                                                                                             Decreased respiratory function, O₂ amount in blood & cilia/macrophage activity  | 
                                                                                 
                                                                                            
                                                                                             Stiffened lung tissue & rib cage  | 
                                                                                 
                                                                                            
                                                                                             Increased COPD/emphysema risk  | 
                                                                                 
                                                                         
                             
    
    
            Key Respiration Terms
        
                        
                                                                                    
                                                                                             Ventilation  | 
                                                                                                                         Respiration  | 
                                                                                 
                                                                                            
                                                                                             Breathing  | 
                                                                                                                         Gas exchange  | 
                                                                                 
                                                                                            
                                                                                            |   | 
                                                                                 
                                                                                            
                                                                                             Inspiration  | 
                                                                                                                        Expiration  | 
                                                                                 
                                                                                            
                                                                                             Inhaling  | 
                                                                                                                         Exhaling  | 
                                                                                 
                                                                                            
                                                                                             Gas exchange between blood & lungs  | 
                                                                                                                         Gas exchange between blood & cells  | 
                                                                                 
                                                                         
                             
    
    
            Gas Exchange (Diffusion)
        
                        
                                                                                    
                                                                                             Gas exchange balances gas pressures on 'both sides'  | 
                                                                                 
                                                                                            
                                                                                            |   | 
                                                                                 
                                                                                            
                                                                                            Partial Pressure (P)  | 
                                                                                 
                                                                                            
                                                                                             Air-caused pressure inside alveoli & blood vessels  | 
                                                                                 
                                                                                            
                                                                                            |   | 
                                                                                 
                                                                                            
                                                                                             Internal Respiration  | 
                                                                                                                        External Respiration  | 
                                                                                 
                                                                                            
                                                                                             Between blood & cells  | 
                                                                                                                         Between blood & alveoli  | 
                                                                                 
                                                                                            
                                                                                             O₂ from blood to cells  | 
                                                                                                                         O₂ from alveoli to blood  | 
                                                                                 
                                                                                            
                                                                                             CO₂ from cells to blood  | 
                                                                                                                         CO₂ from blood to alveoli  | 
                                                                                 
                                                                         
                             
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            Upper Respiratory Tract (URT)
        
                        
                                                                                    
                                                                                             Organs Of URT  | 
                                                                                 
                                                                                            
                                                                                             Nasal cavity  | 
                                                                                 
                                                                                            
                                                                                             Pharynx  | 
                                                                                 
                                                                                            
                                                                                             Trachea  | 
                                                                                 
                                                                                            
                                                                                             Mouth  | 
                                                                                 
                                                                                            
                                                                                             Larynx  | 
                                                                                 
                                                                                            
                                                                                            |   | 
                                                                                 
                                                                                            
                                                                                             Roles  | 
                                                                                 
                                                                                            
                                                                                             Prevents infection  | 
                                                                                 
                                                                                            
                                                                                             Warms/cools air (via nasal cavity & pharynx)  | 
                                                                                 
                                                                                            
                                                                                             Cleans air (via mucous, nose hairs, cilia, tonsils and epiglottis)  | 
                                                                                 
                                                                                            
                                                                                             Humidifies air (via mucous)  | 
                                                                                 
                                                                         
                             
    
    
            Nose & Nasal Cavity (URT)
        
                        
                                                                                    
                                                                                             Lined by epithelial tissues and goblet cells  | 
                                                                                 
                                                                                            
                                                                                             Highly vascular  | 
                                                                                 
                                                                                            
                                                                                            |   | 
                                                                                 
                                                                                            
                                                                                            Nose Hairs: Traps pathogens, dirt & dust  | 
                                                                                 
                                                                         
                             
    
    
            Pharynx (URT)
        
                        
                                                                                    
                                                                                             Sections  | 
                                                                                 
                                                                                            
                                                                                             Nasopharynx: Back of nasocavity  | 
                                                                                 
                                                                                            
                                                                                             Oropharynx: Back of oral cavity  | 
                                                                                 
                                                                                            
                                                                                             Laryngopharynx: Joins the larynx  | 
                                                                                 
                                                                                            
                                                                                            |   | 
                                                                                 
                                                                                            
                                                                                             Functions/Properties  | 
                                                                                 
                                                                                            
                                                                                             Passage for air and food  | 
                                                                                 
                                                                                            
                                                                                             Highly vascular  | 
                                                                                 
                                                                                            
                                                                                             Has goblet cells  | 
                                                                                 
                                                                                            
                                                                                             Fights infections via tonsils  | 
                                                                                 
                                                                         
                             
    
    
            Larynx (URT)
        
                        
                                                                                    
                                                                                             Produces speech  | 
                                                                                 
                                                                                            
                                                                                             Contains voice box & vocal cords  | 
                                                                                 
                                                                                            
                                                                                             Epiglottis seals off trachea when swallowing  | 
                                                                                 
                                                                                            
                                                                                             Has goblet cells  | 
                                                                                 
                                                                         
                             
    
    
            Neural Control Of Breathing
        
                        
                                                                                    
                                                                                             Main Brain Structures Involved  | 
                                                                                 
                                                                                            
                                                                                            |   | 
                                                                                 
                                                                                            
                                                                                            Medulla Oblongata  | 
                                                                                 
                                                                                            
                                                                                             For normal, passive breathing  | 
                                                                                 
                                                                                            
                                                                                             Automatic signal spot  | 
                                                                                 
                                                                                            
                                                                                             Signals from inspiration centre contract diaphragm & intercostal muscles  | 
                                                                                 
                                                                                            
                                                                                            |   | 
                                                                                 
                                                                                            
                                                                                            Pons  | 
                                                                                 
                                                                                            
                                                                                             Increases breathing rate by overriding medulla oblongata's automatic signals  | 
                                                                                 
                                                                                            
                                                                                             Accommodates for exercise, fear etc.  | 
                                                                                 
                                                                         
                             
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            Trachea (LRT)
        
                        
                                                                                    
                                                                                             Main passage for air  | 
                                                                                 
                                                                                            
                                                                                             Has cilia (stimulates cough reflex)  | 
                                                                                 
                                                                                            
                                                                                            |   | 
                                                                                 
                                                                                            
                                                                                             C-Shaped Cartilage Rings  | 
                                                                                 
                                                                                            
                                                                                             Surrounds trachea  | 
                                                                                 
                                                                                            
                                                                                             Allows food accomodation  | 
                                                                                 
                                                                                            
                                                                                             Holds trachea open  | 
                                                                                 
                                                                         
                             
    
    
            Bronchi (LRT)
        
                        
                                                                                    
                                                                                             Both have cartilage rings  | 
                                                                                 
                                                                                            
                                                                                            |   | 
                                                                                 
                                                                                            
                                                                                             Right Bronchus  | 
                                                                                                                         Left Bronchus  | 
                                                                                 
                                                                                            
                                                                                             Shorter, wider & more vertical  | 
                                                                                                                         2x longer than right  | 
                                                                                 
                                                                                            
                                                                                             Common site for foreign objects  | 
                                                                                                                         Narrower  | 
                                                                                 
                                                                         
                             
    
    
            Bronchioles (LRT)
        
                        
                                                                                    
                                                                                             Branches off bronchi  | 
                                                                                 
                                                                                            
                                                                                             Air passage  | 
                                                                                 
                                                                                            
                                                                                             Has goblet cells  | 
                                                                                 
                                                                                            
                                                                                             Surrounded & lined by smooth muscle  | 
                                                                                 
                                                                         
                             
    
    
            Pleura (LRT)
        
                        
                                                                                    
                                                                                             Double-layered lining  | 
                                                                                 
                                                                                            
                                                                                             Fluid-filled  | 
                                                                                 
                                                                         
                             
    
    
            Alveoli (LRT)
        
                        
                                                                                    
                                                                                             Grape-like air sacs at end of bronchioles  | 
                                                                                 
                                                                                            
                                                                                             1 cell thick  | 
                                                                                 
                                                                                            
                                                                                             Surrounded by capillaries  | 
                                                                                 
                                                                         
                             
    
    
            O₂ Saturations
        
                        
                                                                                    
                                                                                             Oxygen % in area of measurement  | 
                                                                                 
                                                                                            
                                                                                            |   | 
                                                                                 
                                                                                            
                                                                                            O₂ Saturation Unit:  SpO₂  | 
                                                                                 
                                                                                            
                                                                                            |   | 
                                                                                 
                                                                                            
                                                                                             O₂ Saturation Ranges  | 
                                                                                 
                                                                                            
                                                                                             Normal: 97-100%  | 
                                                                                 
                                                                                            
                                                                                             Low: 90-96%  | 
                                                                                 
                                                                                            
                                                                                             Critical: 89% and below  | 
                                                                                 
                                                                         
                             
    
    
            Respirations (R or RR)
        
                        
                                                                                    
                                                                                             Normal Rate (No. Breaths/Min)  | 
                                                                                 
                                                                                            
                                                                                             Adults: 12-20 (16 average)  | 
                                                                                 
                                                                                            
                                                                                             Children: 20-28 (22 average)  | 
                                                                                 
                                                                                            
                                                                                            |   | 
                                                                                 
                                                                                            
                                                                                             Rhythm (Regularity)  | 
                                                                                 
                                                                                            
                                                                                             Normal or irregular  | 
                                                                                 
                                                                                            
                                                                                            |   | 
                                                                                 
                                                                                            
                                                                                             Depth (Breath Deepness)  | 
                                                                                 
                                                                                            
                                                                                             Shallow, normal or deep  | 
                                                                                 
                                                                                            
                                                                                            |   | 
                                                                                 
                                                                                            
                                                                                             Sounds  | 
                                                                                 
                                                                                            
                                                                                             Normal: None  | 
                                                                                 
                                                                                            
                                                                                             Abnormal: Wheezing, bubbling, crackling and/or stridor  | 
                                                                                 
                                                                         
                             
    
    
            Temperature
        
                        
                                                                                    
                                                                                             Peripheral Temperature  | 
                                                                                                                         Core Temperature  | 
                                                                                 
                                                                                            
                                                                                             Recorded from surface  | 
                                                                                                                         Recorded from body's center  | 
                                                                                 
                                                                                            
                                                                                            |   | 
                                                                                 
                                                                                            
                                                                                            Temperature Ranges  | 
                                                                                 
                                                                                            
                                                                                             Normal: 36℃ - 37.4℃  | 
                                                                                 
                                                                                            
                                                                                             Low: Below 35℃  | 
                                                                                 
                                                                                            
                                                                                             High: 38℃ and above  | 
                                                                                 
                                                                                            
                                                                                            |   | 
                                                                                 
                                                                                            
                                                                                             Low Temperature  | 
                                                                                                                         High Temperature  | 
                                                                                 
                                                                                            
                                                                                             Name: Hypothermia  | 
                                                                                                                         Name:   Hyperthermia, pyrexia or febrile  | 
                                                                                 
                                                                                            
                                                                                             Causes: Shock,  liver/kidney disease, extreme cold,   hyperthyroidism  | 
                                                                                                                         Causes: Infection, heat stroke, virus  | 
                                                                                 
                                                                         
                             
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