This is a draft cheat sheet. It is a work in progress and is not finished yet.
PROTEINS & PEPTIDES
Recombinant proteins - fastest growing class of pharmaceuticals.
ie. recombinant human insulin
-large , complex and unstable |
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IMMUNOGLOBULINS & MABS
IG- glycoprotien antibodies
Polyclonal serun IgG -passive immunity
mAbs-purified antibodies that bind to single epitope on an antigen.
-from mouse hybridoma cells form transgenic mice
- to target CANCER cells & AUTOIMMUNE Dx
- act as antagonist by binding to antigen and or by binding to cell surface markers on target cells -->cell death by
antibody-dependent cell mediated cytotoxicity & complement-dependent cytotoxicity
-umab - human
-ximab- chimeric
-zumab - humanized |
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