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Metabolic disorders Cheat Sheet (DRAFT) by

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This is a draft cheat sheet. It is a work in progress and is not finished yet.

Obesity

1) Garcinia pericarp "­Malabar tamari­nd"
2)Kelp thallus "­Fucus vesicu­los­us"
3) Psyllu­im"p­lantago seeds"
4) Green "­unr­oas­ted­"­coffee beans
5) Guar gum "­Cya­mopsis tetrag­ono­lob­us"
6) Chitosan
AI: 30% hydrox­ycitric acid (HCA)
AI: Iodine, Polysa­cca­rides (alginate, fucoidan)
The ripe seeds are used. Caution: ground seeds are not used beacuse the seed coat pigment accumu­lates in kidney tubules.
AI: chloro­genic acid & caffeine
AI: Polysa­cch­arides of D-gaaa­ctose & D-mannose, fiber
Not a herbal product. It's a fibrous substance from exoske­leton of crusta­ceans.
MOA: - inhibits ATP-ci­trate lyase-­-> inhibits acetyl coA format­ion­--> no FA (reduced lipoge­nesis)
-Inhibits pancreatic alpha amylase & intestinal alpha glucos­ida­se-­-> appetite suppre­ssion
- Increases hepatic glycogen stores
MOA: Iodine increases thyroid hormon­es-­-> increases choles­terol & carboh­ydrates metabo­lism, enhanced lipolytic response)
- Polysa­cch­arides reduce fat absorption
- Expands in stomach (satia­ting)
- Fiber supple­ments bind to fat & carboh­ydr­ate­s--> reduced absorption
- Mucilage increases elimin­ation, so reduced intesitnal fat absorption
- Thermo­genisis & lipolysis
-Inhibits a-gluc­osidase -Prevents fat storage
MOA: given with meals to reduce glucose & C blood levels - Fibers reduce food absorption
MOA: binds and reduces fat absorp­tion.
No CNS effects (increased accept­abi­lity)

Diabetes mellitus

1) Gymnema
2) Bitter melon seeds (karela) "­Mom­ordica charan­tia­"
3) Opuntia
4) Heglig "­Bal­anites aegypt­iac­"
5) Fenugreek "­Tri­gonella foenum­-gr­aec­um"
AI: gymnemic acid
AI: steroidal glycos­ides, bitter principles (cucur­bit­acins, polype­ptide P, terpen­oids)
AI: high m.wt. polysa­cch­arides
AI: furano­cou­marins, sugar, organic a', saponins
AI: Trigon­elline (N-methyl. deriv. of nicotinic acid)
MOA: - Increase insulin (either its secretion or regene­rating pancreas cells)
- Increases glucose uptake - Reduces glucose absorption
MOA: the bitter principles are insuli­no-­mimetic (SC).
- increases glucose uptake and storage in ms. & liver & reduced its intestinal absorption
MOA: reduces glucose & choles­terol absorption
MOA: anti-h­ype­rgl­ycemic
MOA: increases glucose uptake.
Uses: hypogl­ycemic & weight loss
Uses: hypogl­ycemic (DM2 & insulin resistance specf.)

E defi.

1) Soy, glycine mix
2) Red clover "­Tri­folium praten­se"
3) Evening primrose oil (EPO)
AI: isofla­vones, saponis
AI: isofla­vones
AI: GLA
   
MOA: precursor of PGE1

Menstrual pain ttt.

Emmena­gogues: stimulate blood flow to pelvis & uterus.
Mugwort, parsley, ginger "­Zin­giber off." (most used), chamomile, cinnamon, basil "­Ocimum basili­cum­"
Menstrual pain due to prosta­gla­ndins causing uterus contra­ctions.