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Cheatography

PHAR1101-Alcohol Cheat Sheet (DRAFT) by

This is a draft cheat sheet. It is a work in progress and is not finished yet.

Histor­y-Egypt

Made from
Barley
Consum­ption
Beer and bread were a staple part of the diet
Economic Use
May have be used as currency
Cleopatra 7th imposed a beer tax
Religious Ties
Containers of beer placed in burial chamber
Brewing would occur in temples
Social Ties
General anti-a­lco­holism attitude
ancient paintings and texts warn of drunke­nness, vomiting and alcoholic abuse ,

Effects on the brain

Is a psycho­active ingredient
Targets nervous system
not a stimulant
Non-se­lective depressant
 

Histor­y-Rome

Made from
Grapes (Wine)
Economics
Extensive trade of wine
Consum­ption
Daily consum­ption for all people (inc women and children)
Social ties
Strong acceptance of social ties

Types of Alcohol

Beer
4.6%
High Sugar content
Most popular alcoholic beverage
Wine
10-14%
Made from grapes, berries, stone fruits
Longer fermen­tation time
Spirits
25-50%
Distilled alcohol
Fortified Wine
18-20%
Wine+S­pirit
 

Spirit­+Fo­rtified Wine Examples

Rum
Sugarcane
Vodka
Potato, Grains, Fruits
Whiskey
Fermented grain mash
Port
Wine + Neutral grape spirit
Sherry
Wine + Brandy

Pharma­cok­inetic Qualities

Mixture of Fat and Water solubility
Rapid absorption
Wide tissue penetr­ation

Absorption

Rapid absorb­ance, 30~ mins

mostly absorbed in the upper intestine, but some in the stomach

BAC is directly linked to amount ingested

Distri­bution

Wide distri­bution into body water all throughout the body. Little penetr­ation into fat

Metabolism

Metabo­lised in the gut wall and liver
95% metabo­lised by alcohol dehydrogenase.
Alcohol -> acetal­dehyde -> Acetic acid
Alcohol is saturated in normal condit­ions. Meaning there is a fixed amount that can be metabo­lised per hour
Heavy drinkers have a different metabolism path. Endopl­asmic reticulum is boosted

Excretion

Small amount of alcohol is excreted via the kidneys, and some is also excreted by breath.
Due to genetics some people may excrete more alcohol via breath, which may lead to inaccurate breath­alyser results