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Cheatography

Liver cirrhosis Cheat Sheet (DRAFT) by

A work up on liver cirrhosis

This is a draft cheat sheet. It is a work in progress and is not finished yet.

Definition

Liver cirrhosis is charac­terized by fibrosis and nodule formation of the liver, secondary to a chronic injury, leading to an alteration of the normal lobar organi­zation of the liver. Various insults of injur the liver including viral infex, toxins, hereditary conditions or autoimmune processes. With each injury, the liver forms scar tissue (fibrosis) initially without losing its function. After long standing injury, most of the liver tissue gets fibrosed -> leading to loss of function + cirrhosis develo­pment

Etiology

Chronic liver disease
most common Developed countries: Hepatitis C virus (HCV), ALD, NASH Undeve­loped countries: Hepatitis B (HBV) + HCV
Other causes Autoimmune hepatitis, Primary biliary cholan­gitis, primary sclerosing cholaitis, hemoch­rom­atosis, Wilson disease etc Crypto­genic (cirrhosis of unknown origin)

Epider­miology

Worldwide prevalence remains unknown