This is a draft cheat sheet. It is a work in progress and is not finished yet.
Risk Factors
Sodium consumption |
Inflammation |
Natriuretic peptide abnormalities |
Obesity |
Insulin resistance |
Complications
Myocardial hypertrophy |
CHF |
CKD |
Stroke |
Retinopathy |
Arterial pressure regulation
ANS |
RAAS |
Baroreceptor reflex |
Kidneys |
Natriuretic peptides (dilation) |
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Loop diuretics
Acts on ascending loop |
Blocks reabsorption of Na |
Uses: |
Pulmonary edema |
Edematous states |
Hypertension |
AE: |
Hypo-K/Na |
Ototoxicity |
Dehydration |
Hyperglycemia/urecmia |
Thiazide
Decrease reabsorption of Na, Cl, K, H2O |
early distal convoluted tubule |
Maximal diuresis less than loop |
Not effective with scant u/o |
Uses |
HTN |
Edema |
Diabetes insipidus |
AE |
Hypo-Na/Cl/K |
Dehydration |
Hyperglycemia/uricemia |
Diuretics - AE
Hypovolemia |
Acid-base imbalance |
Electrolyte imbalances |
Potassium-sparing
does not increase u/o |
Not used alone |
Prevents cardiac remodelling |
Blocks aldosterone in nephron |
Uses |
HTN (intially) |
HF |
AE |
Hyper K |
Tumors |
Endocrine effects |
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