Anorexia
Definition |
Loss of appetite |
Causes |
Food odors Drugs Stress Psychological problems Fear Illness |
Pathophysiology and Etiology |
The appetite center in the hypothalamus stimulates or suppresses appetite |
Signs and Symptoms |
The most common: No hunger No desire to eat Nauseous from the smell or thought of food Eat small amounts by obligation or coercion Hypovitaminosis |
Diagnostic Findings |
Hemoglobin and blood cell counts Abnormally enlarged RBCs Serum albumin, electrolyte, and protein w/ cardiac dysrhythmias |
Medical and Surgical Management |
If anorexia is severe |
High-calorie diet, high-calorie supplemental feedings, tube feedings, and total parenteral nutrition (TPN) |
Nursing Management |
Monitor weight daily, monitor I&O, and compile a dietary history |
|
|
Nausea and Vomiting
Pathophysiology and Etiology |
The vomiting center in the medulla is sensitive to parasympathetic neurotransmitters released in response to gastric irritation |
Causes |
Drugs, infections and inflammatory conditions of the GI tract, intestinal obstruction, systemic infections, lesions of the central nervous system, food poisoning, stress, early pregnancy, and uremia |
Nausea |
nauseavomiting usually results from distention of duodenum accompanying symptoms: salivation and peripheral vasoconstriction cold and clammy skin and tachycardia |
The Valsava Maneuver |
Accompanies the forceful expulsion of stomach contents Causes dizziness, hypotension, and bradycardia |
Signs and Symptoms |
Nausea Loss of appetite and refusal to eat Retching vomiting Polydipsia and oliguria r/t dehydration Dry and dull eyes/oral mucosa and poor skin turgor r/t fluid loss Ingestion of noxious substances: excessive alcohol, contaminated food, or drugs w/ GI side effects |
Diagnostic Findings |
serum sodium and chloride bicarbonate levels to compensate loss of chloride and accumulation of metabolic acids hematocrit due to hemoconcentration caused by dehydration |
Medical and Surgical Management |
IV fluids, electrolyte replacement, and drug therapy if n/v is severe Elimination of the cause Symptomatic relief using antiemetics |
|
|
Antiemetic Medications
Serotonin (5-HT3) Receptor Antagonists |
Examples |
Ondansetron (Zofran) Palonosetron (Aloxi) Granisetron |
Uses |
Chemotherapy nausea, post-op vomiting, hyperemesis in pregnancy |
Action |
Blocks neural receptors for 5HT3 |
|