\documentclass[10pt,a4paper]{article} % Packages \usepackage{fancyhdr} % For header and footer \usepackage{multicol} % Allows multicols in tables \usepackage{tabularx} % Intelligent column widths \usepackage{tabulary} % Used in header and footer \usepackage{hhline} % Border under tables \usepackage{graphicx} % For images \usepackage{xcolor} % For hex colours %\usepackage[utf8x]{inputenc} % For unicode character support \usepackage[T1]{fontenc} % Without this we get weird character replacements \usepackage{colortbl} % For coloured tables \usepackage{setspace} % For line height \usepackage{lastpage} % Needed for total page number \usepackage{seqsplit} % Splits long words. %\usepackage{opensans} % Can't make this work so far. Shame. Would be lovely. \usepackage[normalem]{ulem} % For underlining links % Most of the following are not required for the majority % of cheat sheets but are needed for some symbol support. \usepackage{amsmath} % Symbols \usepackage{MnSymbol} % Symbols \usepackage{wasysym} % Symbols %\usepackage[english,german,french,spanish,italian]{babel} % Languages % Document Info \author{Tblue1132} \pdfinfo{ /Title (patho-pharm-quiz-2.pdf) /Creator (Cheatography) /Author (Tblue1132) /Subject (Patho/pharm quiz 2 Cheat Sheet) } % Lengths and widths \addtolength{\textwidth}{6cm} \addtolength{\textheight}{-1cm} \addtolength{\hoffset}{-3cm} \addtolength{\voffset}{-2cm} \setlength{\tabcolsep}{0.2cm} % Space between columns \setlength{\headsep}{-12pt} % Reduce space between header and content \setlength{\headheight}{85pt} % If less, LaTeX automatically increases it \renewcommand{\footrulewidth}{0pt} % Remove footer line \renewcommand{\headrulewidth}{0pt} % Remove header line \renewcommand{\seqinsert}{\ifmmode\allowbreak\else\-\fi} % Hyphens in seqsplit % This two commands together give roughly % the right line height in the tables \renewcommand{\arraystretch}{1.3} \onehalfspacing % Commands \newcommand{\SetRowColor}[1]{\noalign{\gdef\RowColorName{#1}}\rowcolor{\RowColorName}} % Shortcut for row colour \newcommand{\mymulticolumn}[3]{\multicolumn{#1}{>{\columncolor{\RowColorName}}#2}{#3}} % For coloured multi-cols \newcolumntype{x}[1]{>{\raggedright}p{#1}} % New column types for ragged-right paragraph columns \newcommand{\tn}{\tabularnewline} % Required as custom column type in use % Font and Colours \definecolor{HeadBackground}{HTML}{333333} \definecolor{FootBackground}{HTML}{666666} \definecolor{TextColor}{HTML}{333333} \definecolor{DarkBackground}{HTML}{5C53E6} \definecolor{LightBackground}{HTML}{F4F4FD} \renewcommand{\familydefault}{\sfdefault} \color{TextColor} % Header and Footer \pagestyle{fancy} \fancyhead{} % Set header to blank \fancyfoot{} % Set footer to blank \fancyhead[L]{ \noindent \begin{multicols}{3} \begin{tabulary}{5.8cm}{C} \SetRowColor{DarkBackground} \vspace{-7pt} {\parbox{\dimexpr\textwidth-2\fboxsep\relax}{\noindent \hspace*{-6pt}\includegraphics[width=5.8cm]{/web/www.cheatography.com/public/images/cheatography_logo.pdf}} } \end{tabulary} \columnbreak \begin{tabulary}{11cm}{L} \vspace{-2pt}\large{\bf{\textcolor{DarkBackground}{\textrm{Patho/pharm quiz 2 Cheat Sheet}}}} \\ \normalsize{by \textcolor{DarkBackground}{Tblue1132} via \textcolor{DarkBackground}{\uline{cheatography.com/93559/cs/20648/}}} \end{tabulary} \end{multicols}} \fancyfoot[L]{ \footnotesize \noindent \begin{multicols}{3} \begin{tabulary}{5.8cm}{LL} \SetRowColor{FootBackground} \mymulticolumn{2}{p{5.377cm}}{\bf\textcolor{white}{Cheatographer}} \\ \vspace{-2pt}Tblue1132 \\ \uline{cheatography.com/tblue1132} \\ \end{tabulary} \vfill \columnbreak \begin{tabulary}{5.8cm}{L} \SetRowColor{FootBackground} \mymulticolumn{1}{p{5.377cm}}{\bf\textcolor{white}{Cheat Sheet}} \\ \vspace{-2pt}Published 1st October, 2019.\\ Updated 1st October, 2019.\\ Page {\thepage} of \pageref{LastPage}. \end{tabulary} \vfill \columnbreak \begin{tabulary}{5.8cm}{L} \SetRowColor{FootBackground} \mymulticolumn{1}{p{5.377cm}}{\bf\textcolor{white}{Sponsor}} \\ \SetRowColor{white} \vspace{-5pt} %\includegraphics[width=48px,height=48px]{dave.jpeg} Measure your website readability!\\ www.readability-score.com \end{tabulary} \end{multicols}} \begin{document} \raggedright \raggedcolumns % Set font size to small. Switch to any value % from this page to resize cheat sheet text: % www.emerson.emory.edu/services/latex/latex_169.html \footnotesize % Small font. \begin{multicols*}{3} \begin{tabularx}{5.377cm}{X} \SetRowColor{DarkBackground} \mymulticolumn{1}{x{5.377cm}}{\bf\textcolor{white}{Anti Microbial Drugs Names}} \tn % Row 0 \SetRowColor{LightBackground} \mymulticolumn{1}{x{5.377cm}}{Penicillins} \tn % Row Count 1 (+ 1) % Row 1 \SetRowColor{white} \mymulticolumn{1}{x{5.377cm}}{Cephalosporins} \tn % Row Count 2 (+ 1) % Row 2 \SetRowColor{LightBackground} \mymulticolumn{1}{x{5.377cm}}{Macrolides} \tn % Row Count 3 (+ 1) % Row 3 \SetRowColor{white} \mymulticolumn{1}{x{5.377cm}}{Fluoroquinolones} \tn % Row Count 4 (+ 1) % Row 4 \SetRowColor{LightBackground} \mymulticolumn{1}{x{5.377cm}}{Glycopeptide Antibiotic} \tn % Row Count 5 (+ 1) % Row 5 \SetRowColor{white} \mymulticolumn{1}{x{5.377cm}}{Sulfonamides and Trimethoprim} \tn % Row Count 6 (+ 1) \hhline{>{\arrayrulecolor{DarkBackground}}-} \end{tabularx} \par\addvspace{1.3em} \begin{tabularx}{5.377cm}{X} \SetRowColor{DarkBackground} \mymulticolumn{1}{x{5.377cm}}{\bf\textcolor{white}{Penicilins}} \tn % Row 0 \SetRowColor{LightBackground} \mymulticolumn{1}{x{5.377cm}}{{\bf{Drug Name}}} \tn \mymulticolumn{1}{x{5.377cm}}{\hspace*{6 px}\rule{2px}{6px}\hspace*{6 px}Penicillin G, Penicillin V, Amoxicillin, Ampicillin} \tn % Row Count 3 (+ 3) % Row 1 \SetRowColor{white} \mymulticolumn{1}{x{5.377cm}}{{\bf{Common Name}}} \tn \mymulticolumn{1}{x{5.377cm}}{\hspace*{6 px}\rule{2px}{6px}\hspace*{6 px}Almost all end in "cillin"} \tn % Row Count 5 (+ 2) % Row 2 \SetRowColor{LightBackground} \mymulticolumn{1}{x{5.377cm}}{{\bf{Indications (why we use the drug)}}} \tn \mymulticolumn{1}{x{5.377cm}}{\hspace*{6 px}\rule{2px}{6px}\hspace*{6 px}Pneumonia \{\{nl\}\} Meningitis \{\{nl\}\} Endocarditis \{\{nl\}\} Pharyngitis \{\{nl\}\} Syphilis \{\{nl\}\} Prophylaxis- against bacterial endocarditis in at-risk clients prior to dental procedures} \tn % Row Count 10 (+ 5) % Row 3 \SetRowColor{white} \mymulticolumn{1}{x{5.377cm}}{{\bf{Potential Side Effects}}} \tn \mymulticolumn{1}{x{5.377cm}}{\hspace*{6 px}\rule{2px}{6px}\hspace*{6 px}Diarrhea, epigastric distress, nausea, vomiting, rash, pain at IM injection site, phlebitis at IV injection site} \tn % Row Count 14 (+ 4) % Row 4 \SetRowColor{LightBackground} \mymulticolumn{1}{x{5.377cm}}{{\bf{Life threatening Side Effects}}} \tn \mymulticolumn{1}{x{5.377cm}}{\hspace*{6 px}\rule{2px}{6px}\hspace*{6 px}Allergic reaction(anaphylaxisis) \{\{nl\}\} {\emph{amoxicillin specific}} : seizures (high doses), clostridium difficile (CDIF) assoc. diarrhea} \tn % Row Count 18 (+ 4) % Row 5 \SetRowColor{white} \mymulticolumn{1}{x{5.377cm}}{{\bf{Nursing Implications}}} \tn \mymulticolumn{1}{x{5.377cm}}{\hspace*{6 px}\rule{2px}{6px}\hspace*{6 px}-Ask about allergies to penicillins \{\{nl\}\} -monitor for allergic reaction \{\{nl\}\} assess for infection before and after therapy \{\{nl\}\} -obtain specimen for culture BEFORE therapy \{\{nl\}\} -monitor for bowl function for CDIF and report to PCP \{\{nl\}\} -monitor kidney function(nephrotic) \{\{nl\}\} -if PT is taking PO(by mouth)penicillins advise PT to take with food and finish entire course of antibiotic , even if symptoms are resolved} \tn % Row Count 29 (+ 11) % Row 6 \SetRowColor{LightBackground} \mymulticolumn{1}{x{5.377cm}}{{\bf{mechanism of action}}} \tn \mymulticolumn{1}{x{5.377cm}}{\hspace*{6 px}\rule{2px}{6px}\hspace*{6 px}Binds to bacterial cell wall membrane, causing a cell death . Known as "beta-lactam"} \tn % Row Count 32 (+ 3) \end{tabularx} \par\addvspace{1.3em} \vfill \columnbreak \begin{tabularx}{5.377cm}{X} \SetRowColor{DarkBackground} \mymulticolumn{1}{x{5.377cm}}{\bf\textcolor{white}{Penicilins (cont)}} \tn % Row 7 \SetRowColor{white} \mymulticolumn{1}{x{5.377cm}}{{\bf{Notes}}} \tn \mymulticolumn{1}{x{5.377cm}}{\hspace*{6 px}\rule{2px}{6px}\hspace*{6 px}1\textasciicircum{}st\textasciicircum{} class if antibiotics \{\{nl\}\} high levels of antibiotic resistance to early penicillins \{\{nl\}\}} \tn % Row Count 4 (+ 4) \hhline{>{\arrayrulecolor{DarkBackground}}-} \end{tabularx} \par\addvspace{1.3em} \begin{tabularx}{5.377cm}{X} \SetRowColor{DarkBackground} \mymulticolumn{1}{x{5.377cm}}{\bf\textcolor{white}{Fluoroquinolines}} \tn % Row 0 \SetRowColor{LightBackground} \mymulticolumn{1}{x{5.377cm}}{{\bf{Drug Names}}} \tn \mymulticolumn{1}{x{5.377cm}}{\hspace*{6 px}\rule{2px}{6px}\hspace*{6 px}Ciprofloxacin \{\{nl\}\} Ofloxacin \{\{nl\}\} Moxifloxacin \{\{nl\}\} Levofloxacin \{\{nl\}\} Norfloxacin} \tn % Row Count 3 (+ 3) % Row 1 \SetRowColor{white} \mymulticolumn{1}{x{5.377cm}}{{\bf{Name Commonality}}} \tn \mymulticolumn{1}{x{5.377cm}}{\hspace*{6 px}\rule{2px}{6px}\hspace*{6 px}Almost all end in "oxacin"} \tn % Row Count 5 (+ 2) % Row 2 \SetRowColor{LightBackground} \mymulticolumn{1}{x{5.377cm}}{{\bf{Indication}}} \tn \mymulticolumn{1}{x{5.377cm}}{\hspace*{6 px}\rule{2px}{6px}\hspace*{6 px}-UTI \{\{nl\}\} -respiratory infections \{\{nl\}\} -GI tract infections \{\{nl\}\} -Infections of bones, joints, skin, soft tissues \{\{nl\}\} -Anthrax prophylaxis in those that have inhaled anthrax spores} \tn % Row Count 11 (+ 6) % Row 3 \SetRowColor{white} \mymulticolumn{1}{x{5.377cm}}{{\bf{Potential Side Effects}}} \tn \mymulticolumn{1}{x{5.377cm}}{\hspace*{6 px}\rule{2px}{6px}\hspace*{6 px}Dizziness, headache, insomnia, diarrhea, nausea, Achilles' tendon rupture, phototoxicity (severe sunburn)} \tn % Row Count 15 (+ 4) % Row 4 \SetRowColor{LightBackground} \mymulticolumn{1}{x{5.377cm}}{{\bf{Life threatening Side Effects}}} \tn \mymulticolumn{1}{x{5.377cm}}{\hspace*{6 px}\rule{2px}{6px}\hspace*{6 px}Elevated intracranial pressure(ICP) \{\{nl\}\} seizures \{\{nl\}\} suicidal thoughts \{\{nl\}\} hepatoxicity \{\{nl\}\} Clostriudim Difficule (CDIF) assoc. diarrhea \{\{nl\}\} hypersensitivity reaction \{\{nl\}\} SJS \{\{nl\}\} Torsade de Pointes} \tn % Row Count 21 (+ 6) % Row 5 \SetRowColor{white} \mymulticolumn{1}{x{5.377cm}}{{\bf{Nursling Implications}}} \tn \mymulticolumn{1}{x{5.377cm}}{\hspace*{6 px}\rule{2px}{6px}\hspace*{6 px}-Monitor for allergic reaction \{\{nl\}\} -Assess for infection before and after therapy \{\{nl\}\} -Obtain specimen for culture before therapy \{\{nl\}\} -Monitor for skin rash and SJS \{\{nl\}\} -Monitor bowel function for CDIF assoc. diarrhea \{\{nl\}\} -Advise PT to observe and report swelling, pain, or inflammation at Achilles' tendon side and to stop taking med \{\{nl\}\} -Teach PT to avoid prolonged sun exposure} \tn % Row Count 31 (+ 10) \end{tabularx} \par\addvspace{1.3em} \vfill \columnbreak \begin{tabularx}{5.377cm}{X} \SetRowColor{DarkBackground} \mymulticolumn{1}{x{5.377cm}}{\bf\textcolor{white}{Fluoroquinolines (cont)}} \tn % Row 6 \SetRowColor{LightBackground} \mymulticolumn{1}{x{5.377cm}}{{\bf{Mechanism of Action}}} \tn % Row Count 1 (+ 1) % Row 7 \SetRowColor{white} \mymulticolumn{1}{x{5.377cm}}{Inhibit enzymes necessary for bacterial DNA replication (DNA gyrase and topoisomerase IV)} \tn % Row Count 3 (+ 2) \hhline{>{\arrayrulecolor{DarkBackground}}-} \end{tabularx} \par\addvspace{1.3em} \begin{tabularx}{5.377cm}{X} \SetRowColor{DarkBackground} \mymulticolumn{1}{x{5.377cm}}{\bf\textcolor{white}{Cephalosporins}} \tn % Row 0 \SetRowColor{LightBackground} \mymulticolumn{1}{x{5.377cm}}{{\bf{Drug Name}}} \tn \mymulticolumn{1}{x{5.377cm}}{\hspace*{6 px}\rule{2px}{6px}\hspace*{6 px}1\textasciicircum{}st\textasciicircum{} gen: Cephalexin \{\{nl\}\} 2\textasciicircum{}nd\textasciicircum{} gen: Cefaclor \{\{nl\}\} 3\textasciicircum{}rd\textasciicircum{} gen:Ceftraixone \{\{nl\}\} 4\textasciicircum{}th\textasciicircum{} gen: Cefepime \{\{nl\}\} 5\textasciicircum{}th\textasciicircum{} gen: Ceftaroline} \tn % Row Count 4 (+ 4) % Row 1 \SetRowColor{white} \mymulticolumn{1}{x{5.377cm}}{{\bf{Name Commonaility}}} \tn \mymulticolumn{1}{x{5.377cm}}{\hspace*{6 px}\rule{2px}{6px}\hspace*{6 px}All start with "cef"} \tn % Row Count 6 (+ 2) % Row 2 \SetRowColor{LightBackground} \mymulticolumn{1}{x{5.377cm}}{{\bf{ Indications}}} \tn \mymulticolumn{1}{x{5.377cm}}{\hspace*{6 px}\rule{2px}{6px}\hspace*{6 px}{\emph{Note: dependent on generation}} \{\{nl\}\} -skin and skin structure infections \{\{nl\}\} -bone and joint infections \{\{nl\}\} -complicated and uncomplicated UTIs \{\{nl\}\} -Gynecological infections \{\{nl\}\} -lower respiratory tract infections \{\{nl\}\} - intra-abdominal infections \{\{nl\}\} -septicemia \{\{nl\}\} -meningitis \{\{nl\}\} -Otitis Media \{\{nl\}\} -Perioperative (surgery) prophylaxis} \tn % Row Count 15 (+ 9) % Row 3 \SetRowColor{white} \mymulticolumn{1}{x{5.377cm}}{{\bf{Potential Side Effects}}} \tn \mymulticolumn{1}{x{5.377cm}}{\hspace*{6 px}\rule{2px}{6px}\hspace*{6 px}Pain at IM injection site \{\{nl\}\} phlebitis at IV injection site \{\{nl\}\} rash} \tn % Row Count 18 (+ 3) % Row 4 \SetRowColor{LightBackground} \mymulticolumn{1}{x{5.377cm}}{{\bf{Life threatening Side Effects}}} \tn \mymulticolumn{1}{x{5.377cm}}{\hspace*{6 px}\rule{2px}{6px}\hspace*{6 px}Seizures(at high doses), CDIF associated diarrhea, allergic reaction (anaphylaxis), SJS(Steven-Johnson Syndrome)} \tn % Row Count 22 (+ 4) % Row 5 \SetRowColor{white} \mymulticolumn{1}{x{5.377cm}}{{\bf{Nursing Implications}}} \tn \mymulticolumn{1}{x{5.377cm}}{\hspace*{6 px}\rule{2px}{6px}\hspace*{6 px}-Ask about Allergies both Cephalosporins and Penicillins \{\{nl\}\} -monitor for allergic reactions \{\{nl\}\} -assess for infection before and after therapy \{\{nl\}\} -Obtain specimen for culture before therapy \{\{nl\}\} -Monitor bowel fucntion for CDIF assoc. diarrhea \{\{nl\}\} -Monitor for skin rash frequently and discontinue at 1\textasciicircum{}st\textasciicircum{} sign of use(SJS) \{\{nl\}\} -Monitor for kidney fucntion(nephrotic)} \tn % Row Count 32 (+ 10) \end{tabularx} \par\addvspace{1.3em} \vfill \columnbreak \begin{tabularx}{5.377cm}{X} \SetRowColor{DarkBackground} \mymulticolumn{1}{x{5.377cm}}{\bf\textcolor{white}{Cephalosporins (cont)}} \tn % Row 6 \SetRowColor{LightBackground} \mymulticolumn{1}{x{5.377cm}}{{\bf{Mechanism of Action}}} \tn \mymulticolumn{1}{x{5.377cm}}{\hspace*{6 px}\rule{2px}{6px}\hspace*{6 px}Bind to the bacterial cell wall membrane causing cell death . (Aka beta-lactam)} \tn % Row Count 3 (+ 3) \hhline{>{\arrayrulecolor{DarkBackground}}-} \SetRowColor{LightBackground} \mymulticolumn{1}{x{5.377cm}}{Note: each generation is likely to reach cerebrospinal fluid(CSF), less susceptible to antibiotic resistance and more effective against gram-negative organisms. \newline \newline Common-class because they are broad-spectrum , well tolerated, and easy to administer.} \tn \hhline{>{\arrayrulecolor{DarkBackground}}-} \end{tabularx} \par\addvspace{1.3em} \begin{tabularx}{5.377cm}{X} \SetRowColor{DarkBackground} \mymulticolumn{1}{x{5.377cm}}{\bf\textcolor{white}{{\bf{Sulfonamides \& Trimethoprim}}}} \tn % Row 0 \SetRowColor{LightBackground} \mymulticolumn{1}{x{5.377cm}}{{\bf{Drug Names}}} \tn \mymulticolumn{1}{x{5.377cm}}{\hspace*{6 px}\rule{2px}{6px}\hspace*{6 px}\seqsplit{Trimethoprim-sulfamethoxazole} \{\{nl\}\} Sulfadiazine \{\{nl\}\} Trimethoprim} \tn % Row Count 3 (+ 3) % Row 1 \SetRowColor{white} \mymulticolumn{1}{x{5.377cm}}{{\bf{Name Commonailty}}} \tn \mymulticolumn{1}{x{5.377cm}}{\hspace*{6 px}\rule{2px}{6px}\hspace*{6 px}N/A} \tn % Row Count 5 (+ 2) % Row 2 \SetRowColor{LightBackground} \mymulticolumn{1}{x{5.377cm}}{{\bf{Indications}}} \tn \mymulticolumn{1}{x{5.377cm}}{\hspace*{6 px}\rule{2px}{6px}\hspace*{6 px}-UTI \{\{nl\}\} -Otitis Media \{\{nl\}\} -Chancroid \{\{nl\}\} -Pertussis (Whooping cough) -\{\{nl\}\} -Shingellosis \{\{nl\}\} -Pneumocystic jirovecii pneumonia \{\{nl\}\} -Bronchitis} \tn % Row Count 10 (+ 5) % Row 3 \SetRowColor{white} \mymulticolumn{1}{x{5.377cm}}{{\bf{Potential Side Effects}}} \tn \mymulticolumn{1}{x{5.377cm}}{\hspace*{6 px}\rule{2px}{6px}\hspace*{6 px}Nausea, vomiting, rash, phlebitis} \tn % Row Count 12 (+ 2) % Row 4 \SetRowColor{LightBackground} \mymulticolumn{1}{x{5.377cm}}{{\bf{Life threatening Side Effects}}} \tn \mymulticolumn{1}{x{5.377cm}}{\hspace*{6 px}\rule{2px}{6px}\hspace*{6 px}CDIF assoc diarrhea\{\{nl\}\} Hepatic Necrosis \{\{nl\}\}erythema multiforme \{\{nl\}\} toxic epidermal necrolysis \{\{nl\}\} Agranulocytosis \{\{nl\}\} Aplastic Anemia \{\{nl\}\} Hypersensitivity reaction \{\{nl\}\} SJS} \tn % Row Count 18 (+ 6) % Row 5 \SetRowColor{white} \mymulticolumn{1}{x{5.377cm}}{{\bf{Nursing Implications}}} \tn \mymulticolumn{1}{x{5.377cm}}{\hspace*{6 px}\rule{2px}{6px}\hspace*{6 px}-Assess for infection before and after therapy \{\{nl\}\} -Obtain Specimen for culture before therapy \{\{nl\}\} -Monitor IV site closely \{\{nl\}\} -Monitor for allergic reaction \{\{nl\}\} -Do not administer to PT w/ allergy to sulfa drugs, thiazide diuretics, loop diuretics, solfonylurea-type oral hypoglycemics(glipizide) \{\{nl\}\} -Assess for rash and stop at sign of SJS \{\{nl\}\} -Encourage liberal fluid intake \{\{nl\}\} -Monitor urine output \{\{nl\}\} -DO NOT give to women who are pregnant or breastfeeding, or to infants younger than 2 months \{\{nl\}\} -Monitor K+ levels (hyperkalemia) \{\{nl\}\} -Obtain regular CBC to monitor for hematologic disorders \{\{nl\} -Monitor bowel fucntion for CDIF assoc diarrhea and provide to PCP} \tn % Row Count 34 (+ 16) \end{tabularx} \par\addvspace{1.3em} \vfill \columnbreak \begin{tabularx}{5.377cm}{X} \SetRowColor{DarkBackground} \mymulticolumn{1}{x{5.377cm}}{\bf\textcolor{white}{{\bf{Sulfonamides \& Trimethoprim}} (cont)}} \tn % Row 6 \SetRowColor{LightBackground} \mymulticolumn{1}{x{5.377cm}}{{\bf{Mechanism of Action}}} \tn \mymulticolumn{1}{x{5.377cm}}{\hspace*{6 px}\rule{2px}{6px}\hspace*{6 px}Inhibits bacterial growth by stopping synthesis of tetrahydrofolate, which is essential for DNA, RNA, and protein production} \tn % Row Count 4 (+ 4) \hhline{>{\arrayrulecolor{DarkBackground}}-} \end{tabularx} \par\addvspace{1.3em} \begin{tabularx}{5.377cm}{X} \SetRowColor{DarkBackground} \mymulticolumn{1}{x{5.377cm}}{\bf\textcolor{white}{Macrolides}} \tn % Row 0 \SetRowColor{LightBackground} \mymulticolumn{1}{x{5.377cm}}{{\bf{Drug Name}}} \tn \mymulticolumn{1}{x{5.377cm}}{\hspace*{6 px}\rule{2px}{6px}\hspace*{6 px}Erythromycin \{\{nl\}\} Azithromycin\{\{nl\}\} Clarithromycin} \tn % Row Count 3 (+ 3) % Row 1 \SetRowColor{white} \mymulticolumn{1}{x{5.377cm}}{{\bf{Name Commonalitiy}}} \tn \mymulticolumn{1}{x{5.377cm}}{\hspace*{6 px}\rule{2px}{6px}\hspace*{6 px}Almost all end in "mycin"} \tn % Row Count 5 (+ 2) % Row 2 \SetRowColor{LightBackground} \mymulticolumn{1}{x{5.377cm}}{{\bf{Indications}}} \tn \mymulticolumn{1}{x{5.377cm}}{\hspace*{6 px}\rule{2px}{6px}\hspace*{6 px}Alternative for PTs who have a penicillin allergy \{\{nl\}\} Legionnaries' Disease\{\{nl\}\} Pertuesis(whooping cough) and other respiratory infections \{\{nl\}\} acute diphtheria \{\{nl\}\} chlamydial infections \{\{nl\}\} Pneumonia (due to Mycoplasma pneumoniae) \{\{nl\}\} Streptococcal infections} \tn % Row Count 12 (+ 7) % Row 3 \SetRowColor{white} \mymulticolumn{1}{x{5.377cm}}{{\bf{Potential Side Effects}}} \tn \mymulticolumn{1}{x{5.377cm}}{\hspace*{6 px}\rule{2px}{6px}\hspace*{6 px}Abdominal Pain\{\{nl\}\} Diarrhea \{\{nl\}\} Nausea \{\{nl\}\} Vomitting} \tn % Row Count 15 (+ 3) % Row 4 \SetRowColor{LightBackground} \mymulticolumn{1}{x{5.377cm}}{{\bf{Life-Threatening Side Effects}}} \tn \mymulticolumn{1}{x{5.377cm}}{\hspace*{6 px}\rule{2px}{6px}\hspace*{6 px}Ventricular arrhythmias \{\{nl\}\} Torases de Pointes\{\{nl\}\} Hepatoxicicity\{\{nl\}\} CDIF assoc. diarrhea\{\{nl\}\} acute generalized exanthermatous pustulosis \{\{nl\}\} drug reaction with eosinophilia and systemic symptoms(DRESS) \{\{nl\}\} SJS \{\{nl\}\} toxic epidermal necrolysis} \tn % Row Count 22 (+ 7) % Row 5 \SetRowColor{white} \mymulticolumn{1}{x{5.377cm}}{{\bf{Nursing Implications}}} \tn \mymulticolumn{1}{x{5.377cm}}{\hspace*{6 px}\rule{2px}{6px}\hspace*{6 px}-Monitor for allergic reactions \{\{nl\}\} -Assess for infection before and after therapy \{\{nl\}\} -Obtain specimen for culture before therapy \{\{nl\}\} -Monitor for skin rash frequently and discontinue at first sign of SJS \{\{nl\}\} -May cause increase in certain labs (serum bilirubin, AST,ALT,LDH, alkaline phophatase) \{\{nl\}\}-administer with meals \{\{nl\}\} -monitor for CDIF assoc. diarrhea and report to PCP \{\{nl\}\} -monitor for ototoxicity \{\{nl\}\} -monitor for dysrhythmias \{\{nl\}\} -Erythromycin inhibits metabolism if antihistamines, theophylline, Carbamazepine, warfarin, and digoxin} \tn % Row Count 36 (+ 14) \end{tabularx} \par\addvspace{1.3em} \vfill \columnbreak \begin{tabularx}{5.377cm}{X} \SetRowColor{DarkBackground} \mymulticolumn{1}{x{5.377cm}}{\bf\textcolor{white}{Macrolides (cont)}} \tn % Row 6 \SetRowColor{LightBackground} \mymulticolumn{1}{x{5.377cm}}{{\bf{Mechanism of Action}}} \tn \mymulticolumn{1}{x{5.377cm}}{\hspace*{6 px}\rule{2px}{6px}\hspace*{6 px}Inhibits bacterial protein synthesis} \tn % Row Count 2 (+ 2) \hhline{>{\arrayrulecolor{DarkBackground}}-} \end{tabularx} \par\addvspace{1.3em} \begin{tabularx}{5.377cm}{X} \SetRowColor{DarkBackground} \mymulticolumn{1}{x{5.377cm}}{\bf\textcolor{white}{{\bf{Glycopeptide Antibiotic}}}} \tn % Row 0 \SetRowColor{LightBackground} \mymulticolumn{1}{x{5.377cm}}{{\bf{Drug Names}}} \tn \mymulticolumn{1}{x{5.377cm}}{\hspace*{6 px}\rule{2px}{6px}\hspace*{6 px}Vancomycin} \tn % Row Count 2 (+ 2) % Row 1 \SetRowColor{white} \mymulticolumn{1}{x{5.377cm}}{{\bf{Name Commonality}}} \tn \mymulticolumn{1}{x{5.377cm}}{\hspace*{6 px}\rule{2px}{6px}\hspace*{6 px}N/A} \tn % Row Count 4 (+ 2) % Row 2 \SetRowColor{LightBackground} \mymulticolumn{1}{x{5.377cm}}{{\bf{indications}}} \tn \mymulticolumn{1}{x{5.377cm}}{\hspace*{6 px}\rule{2px}{6px}\hspace*{6 px}-Treatment of potential life-threatening infections when less toxic antiFestive are contraindicated \{\{nl\}\} -Particularly useful in staphylococcal infections (MRSA, methicillin resistant staphylococcus aureus) \{\{nl\}\} -Endocarditis \{\{nl\}\} -Meningitis \{\{nl\}\} -Pneumonia \{\{nl\}\} -Septicemia \{\{nl\}\} -Soft tissue infections in Pt who have allergies to penicillins or infections w/penicillin resistance} \tn % Row Count 14 (+ 10) % Row 3 \SetRowColor{white} \mymulticolumn{1}{x{5.377cm}}{{\bf{Potential Side Effects}}} \tn \mymulticolumn{1}{x{5.377cm}}{\hspace*{6 px}\rule{2px}{6px}\hspace*{6 px}Nephrotoxicity, phlebitis, Nausea, Vomitting, Hypotension, Ototoxicity} \tn % Row Count 17 (+ 3) % Row 4 \SetRowColor{LightBackground} \mymulticolumn{1}{x{5.377cm}}{{\bf{Life Threatening Side Effects}}} \tn \mymulticolumn{1}{x{5.377cm}}{\hspace*{6 px}\rule{2px}{6px}\hspace*{6 px}Hypersensitivity reaction(Anaphylaxis)} \tn % Row Count 19 (+ 2) % Row 5 \SetRowColor{white} \mymulticolumn{1}{x{5.377cm}}{{\bf{Nursing Implications}}} \tn \mymulticolumn{1}{x{5.377cm}}{\hspace*{6 px}\rule{2px}{6px}\hspace*{6 px}-Assess for infection before and after therapy \{\{nl\}\} -Obtain specimen for culture before therapy \{\{nl\}\} -Monitor IV site closely (vanxomycin very irritating) and rotate infusion site \{\{nl\}\} -Monitor BP during therapy for hypotension \{\{nl\}\} -Monitor for otoxcicity (toxic to ear and auditory nerve) \{\{nl\}\} -Monitor for nephrotoxicity \{\{nl\}\} -Monitor for allergic reaction} \tn % Row Count 28 (+ 9) % Row 6 \SetRowColor{LightBackground} \mymulticolumn{1}{x{5.377cm}}{{\bf{Mechanism of Action}}} \tn \mymulticolumn{1}{x{5.377cm}}{\hspace*{6 px}\rule{2px}{6px}\hspace*{6 px}Binds to bacterial cell wall, resulting in cell death} \tn % Row Count 31 (+ 3) \hhline{>{\arrayrulecolor{DarkBackground}}-} \end{tabularx} \par\addvspace{1.3em} % That's all folks \end{multicols*} \end{document}