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\author{Rybak}
\pdfinfo{
  /Title (vets1022-mr-nha-blood.pdf)
  /Creator (Cheatography)
  /Author (Rybak)
  /Subject (VETS1022 Mr.Nha Blood Cheat Sheet)
}

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\noindent
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    {\parbox{\dimexpr\textwidth-2\fboxsep\relax}{\noindent
        \hspace*{-6pt}\includegraphics[width=5.8cm]{/web/www.cheatography.com/public/images/cheatography_logo.pdf}}
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\begin{tabulary}{11cm}{L}
    \vspace{-2pt}\large{\bf{\textcolor{DarkBackground}{\textrm{VETS1022 Mr.Nha Blood Cheat Sheet}}}} \\
    \normalsize{by \textcolor{DarkBackground}{Rybak} via \textcolor{DarkBackground}{\uline{cheatography.com/170879/cs/37244/}}}
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\noindent
\begin{multicols}{3}
\begin{tabulary}{5.8cm}{LL}
  \SetRowColor{FootBackground}
  \mymulticolumn{2}{p{5.377cm}}{\bf\textcolor{white}{Cheatographer}}  \\
  \vspace{-2pt}Rybak \\
  \uline{cheatography.com/rybak} \\
  \end{tabulary}
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  \SetRowColor{FootBackground}
  \mymulticolumn{1}{p{5.377cm}}{\bf\textcolor{white}{Cheat Sheet}}  \\
   \vspace{-2pt}Not Yet Published.\\
   Updated 21st February, 2023.\\
   Page {\thepage} of \pageref{LastPage}.
\end{tabulary}
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  \vspace{-5pt}
  %\includegraphics[width=48px,height=48px]{dave.jpeg}
  Measure your website readability!\\
  www.readability-score.com
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\begin{document}
\raggedright
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\begin{multicols*}{3}

\begin{tabularx}{5.377cm}{x{2.4885 cm} x{2.4885 cm} }
\SetRowColor{DarkBackground}
\mymulticolumn{2}{x{5.377cm}}{\bf\textcolor{white}{Introduction}}  \tn
% Row 0
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\mymulticolumn{2}{x{5.377cm}}{-{\bf{ 7-8\% body weight in mammals}}} \tn 
% Row Count 1 (+ 1)
% Row 1
\SetRowColor{white}
\mymulticolumn{2}{x{5.377cm}}{- {\bf{{\emph{Consists of}}}}:} \tn 
% Row Count 2 (+ 1)
% Row 2
\SetRowColor{LightBackground}
+ {\bf{Plasma}}: \{\{nl\}\} - 45-65\% of blood volume \{\{nl\}\} - Alkaline \{\{nl\}\} - Contain dissolved gases, electrolytes, proteins, CHOs, lipids, hormones. & + {\bf{Formed elements}}: \{\{nl\}\} - Erythrocytes \{\{nl\}\} - Leukocytes \{\{nl\}\} - Thrombocytes \tn 
% Row Count 10 (+ 8)
\hhline{>{\arrayrulecolor{DarkBackground}}--}
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\par\addvspace{1.3em}

\begin{tabularx}{5.377cm}{p{0.4977 cm} p{0.4977 cm} }
\SetRowColor{DarkBackground}
\mymulticolumn{2}{x{5.377cm}}{\bf\textcolor{white}{Erythrocytes}}  \tn
% Row 0
\SetRowColor{LightBackground}
\mymulticolumn{2}{x{5.377cm}}{-{\bf{ Highly specialised}} \{\{nl\}\} Contains hemoglobin\{\{nl\}\} -{}-\textgreater{}Carries O2 and Co2 \{\{nl\}\} Maintains cell shape} \tn 
% Row Count 3 (+ 3)
% Row 1
\SetRowColor{white}
\mymulticolumn{2}{x{5.377cm}}{-{\bf{ Round, biconcave, enucleate (in mammals), 4 -8 Um}}} \tn 
% Row Count 5 (+ 2)
% Row 2
\SetRowColor{LightBackground}
\mymulticolumn{2}{x{5.377cm}}{-** Acidophilic cytoplasm: 60\% water, 40\% Hb} \tn 
% Row Count 6 (+ 1)
% Row 3
\SetRowColor{white}
\mymulticolumn{2}{x{5.377cm}}{-{\bf{ Plastic-like, can conform to capillaries}}} \tn 
% Row Count 7 (+ 1)
% Row 4
\SetRowColor{LightBackground}
\mymulticolumn{2}{x{5.377cm}}{-{\bf{ Most abundant, 120-days life span}}} \tn 
% Row Count 8 (+ 1)
% Row 5
\SetRowColor{white}
\mymulticolumn{2}{x{5.377cm}}{- {\bf{Mammals}}: anucleate \{\{nl\}\} - {\bf{ Other animals}}: nucleate} \tn 
% Row Count 10 (+ 2)
% Row 6
\SetRowColor{LightBackground}
\mymulticolumn{2}{x{5.377cm}}{- In bloodstream as immature form 1st: {\bf{Reticulocyte}} \{\{nl\}\} + Slightly larger \{\{nl\}\} + Methylene blue staining \{\{nl\}\} + Proportion is clinically important} \tn 
% Row Count 14 (+ 4)
\hhline{>{\arrayrulecolor{DarkBackground}}--}
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\par\addvspace{1.3em}

\begin{tabularx}{5.377cm}{x{2.4885 cm} x{2.4885 cm} }
\SetRowColor{DarkBackground}
\mymulticolumn{2}{x{5.377cm}}{\bf\textcolor{white}{Leukocytes}}  \tn
% Row 0
\SetRowColor{LightBackground}
\mymulticolumn{2}{x{5.377cm}}{- {\bf{ Responsible for body's immune response}}} \tn 
% Row Count 1 (+ 1)
% Row 1
\SetRowColor{white}
\mymulticolumn{2}{x{5.377cm}}{- {\bf{ Migrate to other tissues}}: \{\{nl\}\} + Variable cell number \{\{nl\}\} + Clinical importance: infection, inflammation} \tn 
% Row Count 4 (+ 3)
% Row 2
\SetRowColor{LightBackground}
\mymulticolumn{2}{x{5.377cm}}{- {\bf{{\emph{Classified into 2 groups}}}}:} \tn 
% Row Count 5 (+ 1)
% Row 3
\SetRowColor{white}
+ {\emph{Granular leukocytes}}: \{\{nl\}\} - Basophils (blue) \{\{nl\}\} - Neutrophils (white) \{\{nl\}\} - Eosinophils (red) & + {\emph{ Non-granular leukocytes}}: \{\{nl\}\} - Lymphocytes \{\{nl\}\} - Monocytes \tn 
% Row Count 11 (+ 6)
\hhline{>{\arrayrulecolor{DarkBackground}}--}
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\par\addvspace{1.3em}

\begin{tabularx}{5.377cm}{p{0.4977 cm} p{0.4977 cm} }
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\mymulticolumn{2}{x{5.377cm}}{\bf\textcolor{white}{Neutrophils}}  \tn
% Row 0
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\mymulticolumn{2}{x{5.377cm}}{- {\bf{ Most numerous granulocytes}} \{\{nl\}\} {\emph{Most abundant types of leukocyte in carnivores}}} \tn 
% Row Count 2 (+ 2)
% Row 1
\SetRowColor{white}
\mymulticolumn{2}{x{5.377cm}}{- {\bf{ Large: 10 -12 Um}}} \tn 
% Row Count 3 (+ 1)
% Row 2
\SetRowColor{LightBackground}
\mymulticolumn{2}{x{5.377cm}}{- {\bf{ Lightly stained granules (hardly visible, white)}}} \tn 
% Row Count 5 (+ 2)
% Row 3
\SetRowColor{white}
\mymulticolumn{2}{x{5.377cm}}{- {\bf{Nucleus}}: \{\{nl\}\} - Mature: multilobed \{\{nl\}\} - Immature: "U" or "S" shape \{\{nl\}\} - Proportion of immature to mature cells is clinically important} \tn 
% Row Count 8 (+ 3)
% Row 4
\SetRowColor{LightBackground}
\mymulticolumn{2}{x{5.377cm}}{- {\bf{Barr body in female = inactive X chromosome}}} \tn 
% Row Count 9 (+ 1)
% Row 5
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\mymulticolumn{2}{x{5.377cm}}{{\bf{{\emph{FUNCTION}}}}:} \tn 
% Row Count 10 (+ 1)
% Row 6
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\mymulticolumn{2}{x{5.377cm}}{-{\bf{ Phagocytosis of external microorganisms and particles}}: enzymes contained with granules inside degrade them} \tn 
% Row Count 13 (+ 3)
% Row 7
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\mymulticolumn{2}{x{5.377cm}}{- {\bf{Go in large number to deal with infection}}; \{\{nl\}\} {\emph{Main constituent of pus}}} \tn 
% Row Count 15 (+ 2)
% Row 8
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\mymulticolumn{2}{x{5.377cm}}{- {\bf{5-day life span in circulation}}} \tn 
% Row Count 16 (+ 1)
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\mymulticolumn{2}{x{5.377cm}}{\bf\textcolor{white}{Eosinophils}}  \tn
% Row 0
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\mymulticolumn{2}{x{5.377cm}}{{\bf{{\emph{Characteristics}}}}} \tn 
% Row Count 1 (+ 1)
% Row 1
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\mymulticolumn{2}{x{5.377cm}}{-{\bf{ Relatively infrequent}} ( 2-8\% of leukocytes)} \tn 
% Row Count 2 (+ 1)
% Row 2
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\mymulticolumn{2}{x{5.377cm}}{- {\bf{10 - 15 Um}}} \tn 
% Row Count 3 (+ 1)
% Row 3
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\mymulticolumn{2}{x{5.377cm}}{- {\bf{Large, acidophilic granules}} (stained red)} \tn 
% Row Count 4 (+ 1)
% Row 4
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\mymulticolumn{2}{x{5.377cm}}{- {\bf{Bilobed nucleus}}} \tn 
% Row Count 5 (+ 1)
% Row 5
\SetRowColor{white}
\mymulticolumn{2}{x{5.377cm}}{-{\bf{ Granules contain hydrolytic enzymes and perioxidases}}} \tn 
% Row Count 7 (+ 2)
% Row 6
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\mymulticolumn{2}{x{5.377cm}}{{\bf{{\emph{FUNCTION}}}}} \tn 
% Row Count 8 (+ 1)
% Row 7
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\mymulticolumn{2}{x{5.377cm}}{- {\bf{Phagocytose antigen/antibody complexes}} \{\{nl\}\} -{}-\textgreater{} Kill helminth parasites: rest against their body, release contents of granules onto them} \tn 
% Row Count 11 (+ 3)
% Row 8
\SetRowColor{LightBackground}
\mymulticolumn{2}{x{5.377cm}}{- {\bf{Implicated in hypersensitivity reactions}}\{\{nl\}\} Ex: a blood smear from an animal with flea allergy dermatitis will show eosinophilia} \tn 
% Row Count 14 (+ 3)
\hhline{>{\arrayrulecolor{DarkBackground}}--}
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\SetRowColor{DarkBackground}
\mymulticolumn{2}{x{5.377cm}}{\bf\textcolor{white}{Basophils}}  \tn
% Row 0
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\mymulticolumn{2}{x{5.377cm}}{{\bf{{\emph{CHARACTERISTICS}}}}} \tn 
% Row Count 1 (+ 1)
% Row 1
\SetRowColor{white}
\mymulticolumn{2}{x{5.377cm}}{-{\bf{ Rarely encountered}} (1,5\% of leukocytes)} \tn 
% Row Count 2 (+ 1)
% Row 2
\SetRowColor{LightBackground}
\mymulticolumn{2}{x{5.377cm}}{- {\bf{10 -15 Um}}} \tn 
% Row Count 3 (+ 1)
% Row 3
\SetRowColor{white}
\mymulticolumn{2}{x{5.377cm}}{-{\bf{ Precursor for tissues' mast cells}}} \tn 
% Row Count 4 (+ 1)
% Row 4
\SetRowColor{LightBackground}
\mymulticolumn{2}{x{5.377cm}}{-{\bf{ Large, darkly basophilic granules (blue)}}} \tn 
% Row Count 5 (+ 1)
% Row 5
\SetRowColor{white}
\mymulticolumn{2}{x{5.377cm}}{- {\bf{ Granules mostly contain histamine, heparin and serotonin}}} \tn 
% Row Count 7 (+ 2)
% Row 6
\SetRowColor{LightBackground}
\mymulticolumn{2}{x{5.377cm}}{- {\bf{Bilobed nucleus obscured by granules}}} \tn 
% Row Count 8 (+ 1)
% Row 7
\SetRowColor{white}
\mymulticolumn{2}{x{5.377cm}}{{\bf{{\emph{FUNCTIONS}}}}} \tn 
% Row Count 9 (+ 1)
% Row 8
\SetRowColor{LightBackground}
\mymulticolumn{2}{x{5.377cm}}{- {\bf{ Also involved in response to helminth parasites}}} \tn 
% Row Count 11 (+ 2)
% Row 9
\SetRowColor{white}
\mymulticolumn{2}{x{5.377cm}}{-{\bf{ Play a role in activation of a subset of T cells (T lymphocytes)}}} \tn 
% Row Count 13 (+ 2)
% Row 10
\SetRowColor{LightBackground}
\mymulticolumn{2}{x{5.377cm}}{- {\bf{ Implicated in hypersensitivity reactions (asthma, hayfever, anaphalytic shock)}}} \tn 
% Row Count 15 (+ 2)
\hhline{>{\arrayrulecolor{DarkBackground}}--}
\end{tabularx}
\par\addvspace{1.3em}

\begin{tabularx}{5.377cm}{p{0.4977 cm} p{0.4977 cm} }
\SetRowColor{DarkBackground}
\mymulticolumn{2}{x{5.377cm}}{\bf\textcolor{white}{Lymphocytes}}  \tn
% Row 0
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\mymulticolumn{2}{x{5.377cm}}{{\bf{{\emph{CHARACTERISTICS}}}}} \tn 
% Row Count 1 (+ 1)
% Row 1
\SetRowColor{white}
\mymulticolumn{2}{x{5.377cm}}{-{\bf{ Found in blood and lymph}}} \tn 
% Row Count 2 (+ 1)
% Row 2
\SetRowColor{LightBackground}
\mymulticolumn{2}{x{5.377cm}}{- {\bf{ Concentrated in lymphoid tissue}} \{\{nl\}\} -{}-\textgreater{} Lymph nodes, nodules, spleen, Peyer's patches in intestine} \tn 
% Row Count 5 (+ 3)
% Row 3
\SetRowColor{white}
\mymulticolumn{2}{x{5.377cm}}{-{\bf{ Second most abundant types of leukocytes}}} \tn 
% Row Count 6 (+ 1)
% Row 4
\SetRowColor{LightBackground}
\mymulticolumn{2}{x{5.377cm}}{-{\bf{ Ovoid to kidney-shaped nucleus that is almost proportionally large as cytoplasm}}} \tn 
% Row Count 8 (+ 2)
% Row 5
\SetRowColor{white}
\mymulticolumn{2}{x{5.377cm}}{-{\bf{ 2 forms:}} \{\{nl\}\} - Small: 6-9 Um \{\{nl\}\} - Large: 12-15 Um} \tn 
% Row Count 10 (+ 2)
% Row 6
\SetRowColor{LightBackground}
\mymulticolumn{2}{x{5.377cm}}{{\bf{{\emph{FUNCTIONS}}}}} \tn 
% Row Count 11 (+ 1)
% Row 7
\SetRowColor{white}
\mymulticolumn{2}{x{5.377cm}}{- {\bf{ Frontline for immunological defense system}}} \tn 
% Row Count 12 (+ 1)
% Row 8
\SetRowColor{LightBackground}
\mymulticolumn{2}{x{5.377cm}}{-Based on functional grounds, {\bf{3 classes}}: \{\{nl\}\} + {\bf{T Cells}}: responsible for {\bf{cell - mediated immune response}} -{}-\textgreater{} release granules that kill virus-infected and tumour cells; Small lymphocytes \{\{nl\}\} + {\bf{ B Cells:}} {\bf{produce antibodies}} (humoural immune response) \{\{nl\}\} *Subset of B cells are {\bf{Plasma cells}}; Small lymphocytes \{\{nl\}\} + {\bf{Natural killer}}: also do {\bf{cell-mediated immune response}} \{\{nl\}\} -{}-\textgreater{} release granules that kill virus-infected and tumor cells; Large lymphocytes} \tn 
% Row Count 22 (+ 10)
\hhline{>{\arrayrulecolor{DarkBackground}}--}
\end{tabularx}
\par\addvspace{1.3em}

\begin{tabularx}{5.377cm}{p{0.4977 cm} p{0.4977 cm} }
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\mymulticolumn{2}{x{5.377cm}}{\bf\textcolor{white}{Monocytes}}  \tn
% Row 0
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\mymulticolumn{2}{x{5.377cm}}{{\bf{{\emph{CHARACTERISTICS}}}}} \tn 
% Row Count 1 (+ 1)
% Row 1
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\mymulticolumn{2}{x{5.377cm}}{- {\bf{5\% of leukocytes}}} \tn 
% Row Count 2 (+ 1)
% Row 2
\SetRowColor{LightBackground}
\mymulticolumn{2}{x{5.377cm}}{-{\bf{ Largest: 15 - 20 Um}}} \tn 
% Row Count 3 (+ 1)
% Row 3
\SetRowColor{white}
\mymulticolumn{2}{x{5.377cm}}{- {\bf{Large, eccentric nucleus: pale -staining}}} \tn 
% Row Count 4 (+ 1)
% Row 4
\SetRowColor{LightBackground}
\mymulticolumn{2}{x{5.377cm}}{- {\bf{Nuclear shape is variable}}: \{\{nl\}\} - Immature: indented \{\{nl\}\} - Mature: horseshoe-like} \tn 
% Row Count 6 (+ 2)
% Row 5
\SetRowColor{white}
\mymulticolumn{2}{x{5.377cm}}{- {\bf{May have 2 or more nucleoli}}} \tn 
% Row Count 7 (+ 1)
% Row 6
\SetRowColor{LightBackground}
\mymulticolumn{2}{x{5.377cm}}{{\bf{{\emph{FUNCTIONS}}}}} \tn 
% Row Count 8 (+ 1)
% Row 7
\SetRowColor{white}
\mymulticolumn{2}{x{5.377cm}}{-{\bf{ Have little function in circulating blood}}} \tn 
% Row Count 9 (+ 1)
% Row 8
\SetRowColor{LightBackground}
\mymulticolumn{2}{x{5.377cm}}{-{\bf{ Highly motile and phagocytic}}} \tn 
% Row Count 10 (+ 1)
% Row 9
\SetRowColor{white}
\mymulticolumn{2}{x{5.377cm}}{-{\bf{ Leave blood after 3 days}} \{\{nl\}\} -{}-\textgreater{} {\bf{Macrophage}} (free roaming in tissues) \{\{nl\}\}-{}-\textgreater{} {\bf{Histiocytes }}(fixed in tissues)} \tn 
% Row Count 13 (+ 3)
% Row 10
\SetRowColor{LightBackground}
\mymulticolumn{2}{x{5.377cm}}{- {\bf{ Respond to:}} necrotic tissue, microorganisms, inflammination} \tn 
% Row Count 15 (+ 2)
% Row 11
\SetRowColor{white}
\mymulticolumn{2}{x{5.377cm}}{- {\bf{ Also in pus with neutrophils}}} \tn 
% Row Count 16 (+ 1)
% Row 12
\SetRowColor{LightBackground}
\mymulticolumn{2}{x{5.377cm}}{- {\bf{Multinucleate giant cells form by fusion of macrophages}} (reminiscent of osteoclasts)} \tn 
% Row Count 18 (+ 2)
\hhline{>{\arrayrulecolor{DarkBackground}}--}
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\par\addvspace{1.3em}

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\SetRowColor{DarkBackground}
\mymulticolumn{2}{x{5.377cm}}{\bf\textcolor{white}{Thrombocytes}}  \tn
% Row 0
\SetRowColor{LightBackground}
\mymulticolumn{2}{x{5.377cm}}{- {\bf{ Also called Platelets}}} \tn 
% Row Count 1 (+ 1)
% Row 1
\SetRowColor{white}
\mymulticolumn{2}{x{5.377cm}}{- {\bf{ Involved in formation of blood clots}}} \tn 
% Row Count 2 (+ 1)
% Row 2
\SetRowColor{LightBackground}
\mymulticolumn{2}{x{5.377cm}}{- {\bf{ Cytoplasmic fragments of megakaryocyte}}} \tn 
% Row Count 3 (+ 1)
% Row 3
\SetRowColor{white}
\mymulticolumn{2}{x{5.377cm}}{- {\bf{2 -4 Um}}} \tn 
% Row Count 4 (+ 1)
% Row 4
\SetRowColor{LightBackground}
\mymulticolumn{2}{x{5.377cm}}{- {\bf{Often appear in clumps on blood smear}}} \tn 
% Row Count 5 (+ 1)
% Row 5
\SetRowColor{white}
\mymulticolumn{2}{x{5.377cm}}{{\bf{{\emph{FUNCTIONS}}}}} \tn 
% Row Count 6 (+ 1)
% Row 6
\SetRowColor{LightBackground}
\mymulticolumn{2}{x{5.377cm}}{- {\bf{Respond to damaged endothelium in 2 stages:}}} \tn 
% Row Count 7 (+ 1)
% Row 7
\SetRowColor{white}
\mymulticolumn{2}{x{5.377cm}}{+ Stage 1: aggregate to form an immediate plug -{}-\textgreater{} stop hemorrhage} \tn 
% Row Count 9 (+ 2)
% Row 8
\SetRowColor{LightBackground}
\mymulticolumn{2}{x{5.377cm}}{+Stage 2: catalyse formation of fibrin clot -{}-\textgreater{} forms a more permanent seal} \tn 
% Row Count 11 (+ 2)
\hhline{>{\arrayrulecolor{DarkBackground}}--}
\end{tabularx}
\par\addvspace{1.3em}

\begin{tabularx}{5.377cm}{p{0.4977 cm} p{0.4977 cm} }
\SetRowColor{DarkBackground}
\mymulticolumn{2}{x{5.377cm}}{\bf\textcolor{white}{Thrombocytes}}  \tn
% Row 0
\SetRowColor{LightBackground}
\mymulticolumn{2}{x{5.377cm}}{- {\bf{ Also called Platelets}}} \tn 
% Row Count 1 (+ 1)
% Row 1
\SetRowColor{white}
\mymulticolumn{2}{x{5.377cm}}{- {\bf{ Involved in formation of blood clots}}} \tn 
% Row Count 2 (+ 1)
\hhline{>{\arrayrulecolor{DarkBackground}}--}
\end{tabularx}
\par\addvspace{1.3em}


% That's all folks
\end{multicols*}

\end{document}