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% Document Info
\author{Roxanne (Reuben)}
\pdfinfo{
  /Title (drug-classes-and-actions-antihistamines.pdf)
  /Creator (Cheatography)
  /Author (Roxanne (Reuben))
  /Subject (Drug Classes \& Actions : Antihistamines Cheat Sheet)
}

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\noindent
\begin{multicols}{3}
\begin{tabulary}{5.8cm}{C}
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    \vspace{-7pt}
    {\parbox{\dimexpr\textwidth-2\fboxsep\relax}{\noindent
        \hspace*{-6pt}\includegraphics[width=5.8cm]{/web/www.cheatography.com/public/images/cheatography_logo.pdf}}
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\begin{tabulary}{11cm}{L}
    \vspace{-2pt}\large{\bf{\textcolor{DarkBackground}{\textrm{Drug Classes \& Actions : Antihistamines Cheat Sheet}}}} \\
    \normalsize{by \textcolor{DarkBackground}{Roxanne (Reuben)} via \textcolor{DarkBackground}{\uline{cheatography.com/69645/cs/18367/}}}
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\noindent
\begin{multicols}{3}
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  \mymulticolumn{2}{p{5.377cm}}{\bf\textcolor{white}{Cheatographer}}  \\
  \vspace{-2pt}Roxanne (Reuben) \\
  \uline{cheatography.com/reuben} \\
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  \mymulticolumn{1}{p{5.377cm}}{\bf\textcolor{white}{Cheat Sheet}}  \\
   \vspace{-2pt}Not Yet Published.\\
   Updated 22nd December, 2018.\\
   Page {\thepage} of \pageref{LastPage}.
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  %\includegraphics[width=48px,height=48px]{dave.jpeg}
  Measure your website readability!\\
  www.readability-score.com
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\end{multicols}}




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\begin{multicols*}{2}

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\mymulticolumn{3}{x{8.4cm}}{\bf\textcolor{white}{Commonly Prescribed For...}}  \tn
% Row 0
\SetRowColor{LightBackground}
Allergic Rhinitis & Hay Fever & Insomnia \tn 
% Row Count 1 (+ 1)
% Row 1
\SetRowColor{white}
Nasal Congestion & \seqsplit{Anaphylaxis} & Urticaria \tn 
% Row Count 2 (+ 1)
% Row 2
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Motion Sickness & Angioedema & Drug Fevers \tn 
% Row Count 3 (+ 1)
% Row 3
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\mymulticolumn{3}{x{8.4cm}}{Parkinson-like Reactions} \tn 
% Row Count 4 (+ 1)
\hhline{>{\arrayrulecolor{DarkBackground}}---}
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\par\addvspace{1.3em}

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\mymulticolumn{1}{x{8.4cm}}{\bf\textcolor{white}{Indications}}  \tn
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\mymulticolumn{1}{x{8.4cm}}{Allergy Symptoms} \tn 
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% Row 1
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% Row Count 2 (+ 1)
% Row 2
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\mymulticolumn{1}{x{8.4cm}}{\seqsplit{Anticholinergic-Properties:} Antihistamines effect the secretions of the lacrimal, salivary, and respiratory mucosal glands.} \tn 
% Row Count 5 (+ 3)
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\end{tabularx}
\par\addvspace{1.3em}

\begin{tabularx}{8.4cm}{X}
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\mymulticolumn{1}{x{8.4cm}}{\bf\textcolor{white}{What is Histamine?}}  \tn
% Row 0
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\mymulticolumn{1}{x{8.4cm}}{{\bf{Released By:}} mast cells, basophils, and other cells in response to antigens circulating in the blood.} \tn 
% Row Count 3 (+ 3)
% Row 1
\SetRowColor{white}
\mymulticolumn{1}{x{8.4cm}}{{\bf{Mechanism Of Action:}} bind to/activate cells in the nose, eyes, respiratory tract, GI tract, and skin, producing characteristic allergic S\&S} \tn 
% Row Count 6 (+ 3)
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\par\addvspace{1.3em}

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\mymulticolumn{1}{x{8.4cm}}{\bf\textcolor{white}{MOA - Receptor Antagonist \& Inverse Agonist}}  \tn
% Row 0
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\mymulticolumn{1}{x{8.4cm}}{{\bf{H Receptor Antagonist}}: Competes with histamine at the unoccupied H receptor sites of basophil and mast cells in the smooth muscle surrounding blood vessels and bronchioles.} \tn 
% Row Count 4 (+ 4)
% Row 1
\SetRowColor{white}
\mymulticolumn{1}{x{8.4cm}}{{\bf{Inverse H Receptor Agonist}}: Binds to the H receptors and instead of taking up the space, induce the opposite effect of a histamine.} \tn 
% Row Count 7 (+ 3)
% Row 2
\SetRowColor{LightBackground}
\mymulticolumn{1}{x{8.4cm}}{{\bf{First Generation}}: Strong sedative effect, can increase the effect of opiods analgesics and some non-opiod analgesics. Can be used as an analgesic itself in some cases (orphenadrine)} \tn 
% Row Count 11 (+ 4)
% Row 3
\SetRowColor{white}
\mymulticolumn{1}{x{8.4cm}}{{\bf{Second Generation}}: Less likely to cause adverse effects on the heart, central nervous system and other organs than first generation antihistamines. Have a less sedative effect because they cross the blood-brain barrier slower and act mainly on peripheral receptors. Have a longer duration of action.} \tn 
% Row Count 18 (+ 7)
% Row 4
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\mymulticolumn{1}{x{8.4cm}}{{\bf{Third Generation:}} Stimulant and nootropic effects.} \tn 
% Row Count 20 (+ 2)
% Row 5
\SetRowColor{white}
\mymulticolumn{1}{x{8.4cm}}{{\bf{Fourth Generation}}: Immunomodulatory effects} \tn 
% Row Count 21 (+ 1)
% Row 6
\SetRowColor{LightBackground}
\mymulticolumn{1}{x{8.4cm}}{{\bf{NOTE:}} Antihistamines do not block histamine release, antibody production, or antigen-antibody reactions. They also don't push off histamines from receptor sites.} \tn 
% Row Count 25 (+ 4)
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\mymulticolumn{3}{x{8.4cm}}{\bf\textcolor{white}{Generic \& Trade Names}}  \tn
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Generic\{\{bb\}\} & Trade\{\{bb\}\} & Route\{\{bb\}\} \tn 
% Row Count 2 (+ 2)
% Row 1
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Loratadine & Claritin & Tablet (10mg), Soft Gel Capsule (10mg), Syrup (1mg/ml) \tn 
% Row Count 7 (+ 4)
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% Row Count 9 (+ 1)
% Row 5
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\mymulticolumn{3}{x{8.4cm}}{\{\{bt\}\}{\bf{Traditional}}} \tn 
% Row Count 10 (+ 1)
% Row 6
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\{\{bt\}\}Diphenhydramine \seqsplit{Hydrochloride} & \{\{bt\}\}Aller-Aide®, Allernix®, Benadryl®, others & \{\{bt\}\}caplets, capsules, chewable tablets, liquid, injection, spray, creams, lotions \tn 
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\mymulticolumn{2}{x{8.4cm}}{\bf\textcolor{white}{Name Endings}}  \tn
% Row 0
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-astine & Antihistaminics \tn 
% Row Count 1 (+ 1)
% Row 1
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-azoline & Antihistaminic, local vasoconstrictor \tn 
% Row Count 3 (+ 2)
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% Row Count 5 (+ 2)
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-tadine & H1-receptor antagonists, tricyclic compounds \tn 
% Row Count 7 (+ 2)
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-tidine & H2-receptor antagonists, cimetidine derivatives \tn 
% Row Count 9 (+ 2)
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Impaired Kidney Function & Pyloric Obstruction & BPH \tn 
% Row Count 2 (+ 2)
% Row 1
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MAO Inhibitors & \seqsplit{Anticholinergic} Properties &  \tn 
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CNS Depressants & Sedation Effects &  \tn 
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\mymulticolumn{3}{x{8.4cm}}{CNS Depressants: Alcohol, antidepressants, opiod analgesics, sedatives \& hypnotics}  \tn 
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Paradoxical Excitement & Sedation & \seqsplit{Nervousness} & \seqsplit{Dizziness} \tn 
% Row Count 6 (+ 2)
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\{\{bb\}\}Muscular Weakness & \{\{bb\}\}Restlessness & Seizures\{\{bb\}\} &  \tn 
% Row Count 8 (+ 2)
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\mymulticolumn{4}{x{8.4cm}}{{\bf{Gastrointestinal}}\{\{bb\}\}} \tn 
% Row Count 9 (+ 1)
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\SetRowColor{LightBackground}
\{\{bb\}\}Nausea \& Vomiting & Hepatitis\{\{bb\}\} & \{\{bb\}\}Diarrhea & \{\{bb\}\}Constipation \tn 
% Row Count 11 (+ 2)
% Row 7
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\mymulticolumn{4}{x{8.4cm}}{{\bf{Other}}\{\{bb\}\}} \tn 
% Row Count 12 (+ 1)
% Row 8
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Visual \seqsplit{Disturbances} & \seqsplit{Xerostomia} & \seqsplit{Tinnitus} & Vertigo \tn 
% Row Count 14 (+ 2)
% Row 9
\SetRowColor{white}
Dry Nose \& Throat & Headache & Urinary \seqsplit{Retention} &  \tn 
% Row Count 17 (+ 3)
\hhline{>{\arrayrulecolor{DarkBackground}}----}
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\mymulticolumn{1}{x{8.4cm}}{\bf\textcolor{white}{Assessments}}  \tn
% Row 0
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\mymulticolumn{1}{x{8.4cm}}{{\bf{Nausea \& Vomiting}}: Assess the degree and frequency of nausea and the amount of emesis when administering for nausea and vomiting} \tn 
% Row Count 3 (+ 3)
% Row 1
\SetRowColor{white}
\mymulticolumn{1}{x{8.4cm}}{{\bf{Anxiety}}: Assess mental status, mood, and behavior when administering for anxiety.} \tn 
% Row Count 5 (+ 2)
% Row 2
\SetRowColor{LightBackground}
\mymulticolumn{1}{x{8.4cm}}{{\bf{Pruritus}}: Observe character, location, and size of affected area when administering for pruritis skin conditions.} \tn 
% Row Count 8 (+ 3)
% Row 3
\SetRowColor{white}
\mymulticolumn{1}{x{8.4cm}}{{\bf{Respiratory}}: Assess lung sounds for bronchial secretions. Maintain fluid intake (1500-200ml/day) to decrease viscosity secretions.} \tn 
% Row Count 11 (+ 3)
% Row 4
\SetRowColor{LightBackground}
\mymulticolumn{1}{x{8.4cm}}{{\bf{Allergy Symptoms}}: Assess for this before and periodically throughout treatment.} \tn 
% Row Count 13 (+ 2)
% Row 5
\SetRowColor{white}
\mymulticolumn{1}{x{8.4cm}}{{\bf{IV Therapy}}: Assess BP and RR before and throughout IV therapy.} \tn 
% Row Count 15 (+ 2)
\hhline{>{\arrayrulecolor{DarkBackground}}-}
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\mymulticolumn{2}{x{8.4cm}}{\bf\textcolor{white}{Nursing Diagnosis}}  \tn
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Ineffective Airway Clearence\{\{br\}\} & Indications \tn 
% Row Count 2 (+ 2)
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Risk for Injury \{\{br\}\} & Adverse Reactions \tn 
% Row Count 4 (+ 2)
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Deficiet Knowledge (Disease Process/Medication Regimen)\{\{br\}\} & \seqsplit{Patient/Family} Teaching \tn 
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\mymulticolumn{1}{x{8.4cm}}{\bf\textcolor{white}{Implementation}}  \tn
% Row 0
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% Row Count 3 (+ 3)
% Row 1
\SetRowColor{white}
\mymulticolumn{1}{x{8.4cm}}{{\bf{Concurrent Use w/ Opiod Analgesics}}: Supervise ambulation to prevent injury secondary to increased sedation.} \tn 
% Row Count 6 (+ 3)
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% Row 0
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\mymulticolumn{1}{x{8.4cm}}{{\bf{Drowsiness}}: Inform patient they may feel drowsy. Avoid driving and activities requiring alertness.} \tn 
% Row Count 3 (+ 3)
% Row 1
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\mymulticolumn{1}{x{8.4cm}}{{\bf{Sedation}}: Caution patient to avoid concurrent use of alcohol or CNS depressants.} \tn 
% Row Count 5 (+ 2)
% Row 2
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\mymulticolumn{1}{x{8.4cm}}{{\bf{Xerostomia}}: Advise patient good oral hygiene, frequent mouth rinsing with water, and sugarless gum/candy may relieve from mouth dryness} \tn 
% Row Count 8 (+ 3)
% Row 3
\SetRowColor{white}
\mymulticolumn{1}{x{8.4cm}}{{\bf{Persistent Symptoms}}: Inform patient to contact a health care professional if symptoms persist.} \tn 
% Row Count 10 (+ 2)
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\par\addvspace{1.3em}

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\mymulticolumn{2}{x{8.4cm}}{\bf\textcolor{white}{Evaluation/Desired Outcomes}}  \tn
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Decrease/Prevent nausea & Decrease allergic S\&S \tn 
% Row Count 2 (+ 2)
% Row 1
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Decrease/Prevent vomiting & Relieve pruritus \tn 
% Row Count 4 (+ 2)
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\SetRowColor{LightBackground}
Sedation when used as a hypnotic & Decrease anxiety \tn 
% Row Count 6 (+ 2)
\hhline{>{\arrayrulecolor{DarkBackground}}--}
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\par\addvspace{1.3em}

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\mymulticolumn{1}{x{8.4cm}}{\bf\textcolor{white}{Additional Notes}}  \tn
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% Row Count 9 (+ 1)
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\mymulticolumn{1}{x{8.4cm}}{\bf\textcolor{white}{References}}  \tn
% Row 0
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\mymulticolumn{1}{x{8.4cm}}{Lilley, L.L, Collins, S.R., Snyder, J.S., \& Swart, B. (2017). Pharmacology for Canadian Health Care Practice (2nd Canadian ed.). Toronto: Elsevier Canada.} \tn 
% Row Count 4 (+ 4)
% Row 1
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\mymulticolumn{1}{x{8.4cm}}{Vallerand, A.H., \& Sanoski, C.A. (2018). Davis's Canadian Drug Guide for Nurses (16th ed.). Philadelphia: F.A. Davis.} \tn 
% Row Count 7 (+ 3)
% Row 2
\SetRowColor{LightBackground}
\mymulticolumn{1}{x{8.4cm}}{World Health Organization, WHO. WHO Stembook 2013: The use of stems in the selection of International Nonproprietary Names (INN) for pharmaceutical substances. 2013 {[}cited 22 Dec 2018{]}. Available from: \seqsplit{https://www.who.int/medicines/services/inn/StemBook\_2013\_Final.pdf}} \tn 
% Row Count 13 (+ 6)
% Row 3
\SetRowColor{white}
\mymulticolumn{1}{x{8.4cm}}{\seqsplit{https://www.myvmc.com/medical-dictionary/second-generation-antihistamines/}} \tn 
% Row Count 15 (+ 2)
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\par\addvspace{1.3em}


% That's all folks
\end{multicols*}

\end{document}