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%\usepackage{opensans}          % Can't make this work so far. Shame. Would be lovely.
\usepackage[normalem]{ulem}     % For underlining links
% Most of the following are not required for the majority
% of cheat sheets but are needed for some symbol support.
\usepackage{amsmath}            % Symbols
\usepackage{MnSymbol}           % Symbols
\usepackage{wasysym}            % Symbols
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% Document Info
\author{Natfle}
\pdfinfo{
  /Title (phar1101-3.pdf)
  /Creator (Cheatography)
  /Author (Natfle)
  /Subject (PHAR1101-3 Cheat Sheet)
}

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% Commands
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% Header and Footer
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\fancyhead[L]{
\noindent
\begin{multicols}{3}
\begin{tabulary}{5.8cm}{C}
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    \vspace{-7pt}
    {\parbox{\dimexpr\textwidth-2\fboxsep\relax}{\noindent
        \hspace*{-6pt}\includegraphics[width=5.8cm]{/web/www.cheatography.com/public/images/cheatography_logo.pdf}}
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\columnbreak
\begin{tabulary}{11cm}{L}
    \vspace{-2pt}\large{\bf{\textcolor{DarkBackground}{\textrm{PHAR1101-3 Cheat Sheet}}}} \\
    \normalsize{by \textcolor{DarkBackground}{Natfle} via \textcolor{DarkBackground}{\uline{cheatography.com/86696/cs/20429/}}}
\end{tabulary}
\end{multicols}}

\fancyfoot[L]{ \footnotesize
\noindent
\begin{multicols}{3}
\begin{tabulary}{5.8cm}{LL}
  \SetRowColor{FootBackground}
  \mymulticolumn{2}{p{5.377cm}}{\bf\textcolor{white}{Cheatographer}}  \\
  \vspace{-2pt}Natfle \\
  \uline{cheatography.com/natfle} \\
  \end{tabulary}
\vfill
\columnbreak
\begin{tabulary}{5.8cm}{L}
  \SetRowColor{FootBackground}
  \mymulticolumn{1}{p{5.377cm}}{\bf\textcolor{white}{Cheat Sheet}}  \\
   \vspace{-2pt}Not Yet Published.\\
   Updated 30th August, 2019.\\
   Page {\thepage} of \pageref{LastPage}.
\end{tabulary}
\vfill
\columnbreak
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  \mymulticolumn{1}{p{5.377cm}}{\bf\textcolor{white}{Sponsor}}  \\
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  \vspace{-5pt}
  %\includegraphics[width=48px,height=48px]{dave.jpeg}
  Measure your website readability!\\
  www.readability-score.com
\end{tabulary}
\end{multicols}}




\begin{document}
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% Set font size to small. Switch to any value
% from this page to resize cheat sheet text:
% www.emerson.emory.edu/services/latex/latex_169.html
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\begin{multicols*}{3}

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\mymulticolumn{1}{x{5.377cm}}{\bf\textcolor{white}{Effect of Me-Too Drugs}}  \tn
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\par\addvspace{1.3em}

\begin{tabularx}{5.377cm}{x{1.59264 cm} x{3.38436 cm} }
\SetRowColor{DarkBackground}
\mymulticolumn{2}{x{5.377cm}}{\bf\textcolor{white}{Side Effects of Me-Too Drugs}}  \tn
% Row 0
\SetRowColor{LightBackground}
Crowded Marketplace & too many similar drugs \tn 
% Row Count 2 (+ 2)
% Row 1
\SetRowColor{white}
Stifled innovation & Companies priotise creation of 2nd-gen drugs rather than pursuing new drugs \tn 
% Row Count 5 (+ 3)
% Row 2
\SetRowColor{LightBackground}
Cost & Cost increases \tn 
% Row Count 6 (+ 1)
\hhline{>{\arrayrulecolor{DarkBackground}}--}
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\par\addvspace{1.3em}

\begin{tabularx}{5.377cm}{p{0.54747 cm} x{4.42953 cm} }
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\mymulticolumn{2}{x{5.377cm}}{\bf\textcolor{white}{Example}}  \tn
% Row 0
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Gen 1 & Teprotide \{\{nl\}\} Couldn't be taken by mouth \tn 
% Row Count 2 (+ 2)
% Row 1
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Gen 2 & Captopril \{\{nl\}\} Contains sulfur group, allowing it to be taken by mouth \{\{nl\}\} caused intense itching, loss of taste, dry cough \{\{nl\}\} had to be taken thre times a day \tn 
% Row Count 7 (+ 5)
% Row 2
\SetRowColor{LightBackground}
Gen 3 & Enalapril \{\{nl\}\} doesn't have sulfur \{\{nl\}\} can be taken orally \{\{nl\}\} taken once a day \tn 
% Row Count 10 (+ 3)
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\mymulticolumn{2}{x{5.377cm}}{\bf\textcolor{white}{Effects of Hypertension}}  \tn
% Row 0
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Brain & Stroke \{\{nl\}\} Loss of brain function \{\{nl\}\} Headache \tn 
% Row Count 2 (+ 2)
% Row 1
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\seqsplit{Kidney} & Chronic Failure \{\{nl\}\} Proteins leak into urine \{\{nl\}\} most vulnerable organ \tn 
% Row Count 5 (+ 3)
% Row 2
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\seqsplit{Vessels} & Endothelial damage \tn 
% Row Count 7 (+ 2)
% Row 3
\SetRowColor{white}
Heart & Heart Attack \{\{nl\}\} thickened heart wall \tn 
% Row Count 9 (+ 2)
% Row 4
\SetRowColor{LightBackground}
Eyes & Chronic retina damage \tn 
% Row Count 10 (+ 1)
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\mymulticolumn{2}{x{5.377cm}}{\bf\textcolor{white}{Definitions}}  \tn
% Row 0
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Innovator Drug & The first drug onto the market to meet a previously unmet medical need \tn 
% Row Count 3 (+ 3)
% Row 1
\SetRowColor{white}
Therapeutic Class & A family of drugs that are grouped together based on their use for treating similar diseases \tn 
% Row Count 7 (+ 4)
% Row 2
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Drug Analogue & A molecule with a similar but not identical structure to another drug. Despite similarities they can have very different pharmacological and toxicological properties. \tn 
% Row Count 14 (+ 7)
% Row 3
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Small Molecule Drug & A drug with a molecule mass less than 500 grams. Often cheap to make \tn 
% Row Count 17 (+ 3)
% Row 4
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Dosing Frequency & The number of time a patient has to take a pill everyday. \tn 
% Row Count 20 (+ 3)
% Row 5
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Compliance & The extent to which a person follows the advice of their doctors. Somehow who skips doses shows low compliance \tn 
% Row Count 25 (+ 5)
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\begin{tabularx}{5.377cm}{x{2.43873 cm} x{2.53827 cm} }
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\mymulticolumn{2}{x{5.377cm}}{\bf\textcolor{white}{Me-Too Drug Examples}}  \tn
% Row 0
\SetRowColor{LightBackground}
Amoxicillin \{\{nl\}\} 1964 & From: penicillin \{\{nl\}\} Fixed: Sensitivity to stomach acid \{\{nl\}\} Treats: everyday infenctions \tn 
% Row Count 5 (+ 5)
% Row 1
\SetRowColor{white}
Fexofenadine \{\{nl\}\} 1980 & From: Diphenhydramine \{\{nl\}\} Fixed: Sedation \{\{nl\}\} Treats: antihistamine \tn 
% Row Count 9 (+ 4)
% Row 2
\SetRowColor{LightBackground}
Cefepime \{\{nl\}\} 1983 & From: cephalosporin \{\{nl\}\} Fixed: More suitable killing activity \{\{nl\}\} Treats: life threatening infections \tn 
% Row Count 15 (+ 6)
% Row 3
\SetRowColor{white}
Celecoxib \{\{nl\}\} 1995 & From: Ibuprofen \{\{nl\}\} Fixed: gastrointestinal damage \{\{nl\}\} Treats: anti-inflammatory \tn 
% Row Count 20 (+ 5)
% Row 4
\SetRowColor{LightBackground}
Atorvastatin \{\{nl\}\} Lipitor \{\{nl\}\} 1996 & From: Lovastatin \{\{nl\}\} Fixed: More effective \{\{nl\}\} treats: lowers cholesterol \tn 
% Row Count 24 (+ 4)
% Row 5
\SetRowColor{white}
Atazanavir \{\{nl\}\} 1997 & From: PI'S \{\{nl\}\} Fixed: didn't distrupt lipid metabolism \{\{nl\}\} Treats: AIDS \tn 
% Row Count 28 (+ 4)
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\mymulticolumn{1}{x{5.377cm}}{\bf\textcolor{white}{Side Effects}}  \tn
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\mymulticolumn{1}{x{5.377cm}}{Most drugs cause side effects. Drugs are designed to bind a specific receptor, however they may bind to, and stop the function, of another receptor. this is what causes the side effects. this tendency to bind to multiple receptors is known as non-specificity% Row Count 6 (+ 6)
} \tn 
\hhline{>{\arrayrulecolor{DarkBackground}}-}
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\par\addvspace{1.3em}


% That's all folks
\end{multicols*}

\end{document}