\documentclass[10pt,a4paper]{article} % Packages \usepackage{fancyhdr} % For header and footer \usepackage{multicol} % Allows multicols in tables \usepackage{tabularx} % Intelligent column widths \usepackage{tabulary} % Used in header and footer \usepackage{hhline} % Border under tables \usepackage{graphicx} % For images \usepackage{xcolor} % For hex colours %\usepackage[utf8x]{inputenc} % For unicode character support \usepackage[T1]{fontenc} % Without this we get weird character replacements \usepackage{colortbl} % For coloured tables \usepackage{setspace} % For line height \usepackage{lastpage} % Needed for total page number \usepackage{seqsplit} % Splits long words. %\usepackage{opensans} % Can't make this work so far. Shame. Would be lovely. \usepackage[normalem]{ulem} % For underlining links % Most of the following are not required for the majority % of cheat sheets but are needed for some symbol support. \usepackage{amsmath} % Symbols \usepackage{MnSymbol} % Symbols \usepackage{wasysym} % Symbols %\usepackage[english,german,french,spanish,italian]{babel} % Languages % Document Info \author{Natfle} \pdfinfo{ /Title (phar1101-1.pdf) /Creator (Cheatography) /Author (Natfle) /Subject (PHAR1101-1 Cheat Sheet) } % Lengths and widths \addtolength{\textwidth}{6cm} \addtolength{\textheight}{-1cm} \addtolength{\hoffset}{-3cm} \addtolength{\voffset}{-2cm} \setlength{\tabcolsep}{0.2cm} % Space between columns \setlength{\headsep}{-12pt} % Reduce space between header and content \setlength{\headheight}{85pt} % If less, LaTeX automatically increases it \renewcommand{\footrulewidth}{0pt} % Remove footer line \renewcommand{\headrulewidth}{0pt} % Remove header line \renewcommand{\seqinsert}{\ifmmode\allowbreak\else\-\fi} % Hyphens in seqsplit % This two commands together give roughly % the right line height in the tables \renewcommand{\arraystretch}{1.3} \onehalfspacing % Commands \newcommand{\SetRowColor}[1]{\noalign{\gdef\RowColorName{#1}}\rowcolor{\RowColorName}} % Shortcut for row colour \newcommand{\mymulticolumn}[3]{\multicolumn{#1}{>{\columncolor{\RowColorName}}#2}{#3}} % For coloured multi-cols \newcolumntype{x}[1]{>{\raggedright}p{#1}} % New column types for ragged-right paragraph columns \newcommand{\tn}{\tabularnewline} % Required as custom column type in use % Font and Colours \definecolor{HeadBackground}{HTML}{333333} \definecolor{FootBackground}{HTML}{666666} \definecolor{TextColor}{HTML}{333333} \definecolor{DarkBackground}{HTML}{CCD63A} \definecolor{LightBackground}{HTML}{FBFCF2} \renewcommand{\familydefault}{\sfdefault} \color{TextColor} % Header and Footer \pagestyle{fancy} \fancyhead{} % Set header to blank \fancyfoot{} % Set footer to blank \fancyhead[L]{ \noindent \begin{multicols}{3} \begin{tabulary}{5.8cm}{C} \SetRowColor{DarkBackground} \vspace{-7pt} {\parbox{\dimexpr\textwidth-2\fboxsep\relax}{\noindent \hspace*{-6pt}\includegraphics[width=5.8cm]{/web/www.cheatography.com/public/images/cheatography_logo.pdf}} } \end{tabulary} \columnbreak \begin{tabulary}{11cm}{L} \vspace{-2pt}\large{\bf{\textcolor{DarkBackground}{\textrm{PHAR1101-1 Cheat Sheet}}}} \\ \normalsize{by \textcolor{DarkBackground}{Natfle} via \textcolor{DarkBackground}{\uline{cheatography.com/86696/cs/20245/}}} \end{tabulary} \end{multicols}} \fancyfoot[L]{ \footnotesize \noindent \begin{multicols}{3} \begin{tabulary}{5.8cm}{LL} \SetRowColor{FootBackground} \mymulticolumn{2}{p{5.377cm}}{\bf\textcolor{white}{Cheatographer}} \\ \vspace{-2pt}Natfle \\ \uline{cheatography.com/natfle} \\ \end{tabulary} \vfill \columnbreak \begin{tabulary}{5.8cm}{L} \SetRowColor{FootBackground} \mymulticolumn{1}{p{5.377cm}}{\bf\textcolor{white}{Cheat Sheet}} \\ \vspace{-2pt}Not Yet Published.\\ Updated 12th August, 2019.\\ Page {\thepage} of \pageref{LastPage}. \end{tabulary} \vfill \columnbreak \begin{tabulary}{5.8cm}{L} \SetRowColor{FootBackground} \mymulticolumn{1}{p{5.377cm}}{\bf\textcolor{white}{Sponsor}} \\ \SetRowColor{white} \vspace{-5pt} %\includegraphics[width=48px,height=48px]{dave.jpeg} Measure your website readability!\\ www.readability-score.com \end{tabulary} \end{multicols}} \begin{document} \raggedright \raggedcolumns % Set font size to small. Switch to any value % from this page to resize cheat sheet text: % www.emerson.emory.edu/services/latex/latex_169.html \footnotesize % Small font. \begin{multicols*}{3} \begin{tabularx}{5.377cm}{x{1.29402 cm} x{3.68298 cm} } \SetRowColor{DarkBackground} \mymulticolumn{2}{x{5.377cm}}{\bf\textcolor{white}{Definitions}} \tn % Row 0 \SetRowColor{LightBackground} Bioactive & A substance that when extracted from a plant or biological sources, produces a physiological response after it enters the body of another species \tn % Row Count 5 (+ 5) % Row 1 \SetRowColor{white} \seqsplit{Bioprospecting} & An intentional program of scientific research involving systematic collection of plant-derived matter followed by evaluation of its pharmacological properties using standardised tests \tn % Row Count 12 (+ 7) % Row 2 \SetRowColor{LightBackground} Screening & Systematic use of standardised bioassay method to evaluate a large number of compounds or plants extract for a specific pharmacological action \tn % Row Count 17 (+ 5) % Row 3 \SetRowColor{white} Bioassay & A scientific method that provides information on the concentrations or potency of a substances by assessing its effects individual enzymes living cells or animal tissues \tn % Row Count 23 (+ 6) % Row 4 \SetRowColor{LightBackground} \seqsplit{Pharmacognosy} & the branch of scientific knowledge that is concerned with the study of plant-derived medicines \tn % Row Count 27 (+ 4) \hhline{>{\arrayrulecolor{DarkBackground}}--} \end{tabularx} \par\addvspace{1.3em} \begin{tabularx}{5.377cm}{x{1.14471 cm} x{3.83229 cm} } \SetRowColor{DarkBackground} \mymulticolumn{2}{x{5.377cm}}{\bf\textcolor{white}{Examples of Factors effecting Bioprospecting}} \tn % Row 0 \SetRowColor{LightBackground} Cultural & Legal issues arise when Drug companies try to get IP rights for drugs that have been used in a traditional fashion for native peoples. \tn % Row Count 5 (+ 5) % Row 1 \SetRowColor{white} \seqsplit{Enviromental} & Cinchona: \{\{nl\}\} The high demand for the tree bark caused over harvesting. This led to the slow extinction of the natural forests in south america. after a shortage of quinine during ww2, a synthetic version was created \tn % Row Count 13 (+ 8) % Row 2 \SetRowColor{LightBackground} \mymulticolumn{2}{x{5.377cm}}{Toxicological} \tn % Row Count 14 (+ 1) \hhline{>{\arrayrulecolor{DarkBackground}}--} \end{tabularx} \par\addvspace{1.3em} \begin{tabularx}{5.377cm}{X} \SetRowColor{DarkBackground} \mymulticolumn{1}{x{5.377cm}}{\bf\textcolor{white}{Artemisinins}} \tn \SetRowColor{white} \mymulticolumn{1}{x{5.377cm}}{The Drug discovered by Youyou Tu was named Artemisinin. It contains an endoperoxide Bridge (C-O-O-C), this is similar to hydrogen peroxide. this gives it anti-parasitic properties. the drug is extracted from a strain of Artemisia. The drug is highly effective, but is more effective when partnered with other remedies.% Row Count 7 (+ 7) } \tn \hhline{>{\arrayrulecolor{DarkBackground}}-} \end{tabularx} \par\addvspace{1.3em} \begin{tabularx}{5.377cm}{X} \SetRowColor{DarkBackground} \mymulticolumn{1}{x{5.377cm}}{\bf\textcolor{white}{Steps of Discovery Progress}} \tn % Row 0 \SetRowColor{LightBackground} \mymulticolumn{1}{x{5.377cm}}{Plant Selection} \tn % Row Count 1 (+ 1) % Row 1 \SetRowColor{white} \mymulticolumn{1}{x{5.377cm}}{Extraction Preperation} \tn % Row Count 2 (+ 1) % Row 2 \SetRowColor{LightBackground} \mymulticolumn{1}{x{5.377cm}}{Bioassay Screening} \tn % Row Count 3 (+ 1) % Row 3 \SetRowColor{white} \mymulticolumn{1}{x{5.377cm}}{Compound Identification} \tn % Row Count 4 (+ 1) % Row 4 \SetRowColor{LightBackground} \mymulticolumn{1}{x{5.377cm}}{Animal Testing} \tn % Row Count 5 (+ 1) % Row 5 \SetRowColor{white} \mymulticolumn{1}{x{5.377cm}}{Human Testing} \tn % Row Count 6 (+ 1) % Row 6 \SetRowColor{LightBackground} \mymulticolumn{1}{x{5.377cm}}{Regulatory Approval} \tn % Row Count 7 (+ 1) % Row 7 \SetRowColor{white} \mymulticolumn{1}{x{5.377cm}}{Marketing} \tn % Row Count 8 (+ 1) \hhline{>{\arrayrulecolor{DarkBackground}}-} \end{tabularx} \par\addvspace{1.3em} \begin{tabularx}{5.377cm}{x{1.74195 cm} x{3.23505 cm} } \SetRowColor{DarkBackground} \mymulticolumn{2}{x{5.377cm}}{\bf\textcolor{white}{Types of Secondary Metabolics}} \tn % Row 0 \SetRowColor{LightBackground} Pest Deterrents & Plants produce these chemicals to ward away predators. They leave a fowl taste, and may negatively impact, or kill the predator \tn % Row Count 5 (+ 5) % Row 1 \SetRowColor{white} Growth Regulator & These chemicals regulate the growth of leaves, roots, cells etc. this allows plants to respond quickly to environmental change \tn % Row Count 10 (+ 5) % Row 2 \SetRowColor{LightBackground} Natural Sunblock & Many plants produce a chemical which can absorb high levels of UV radiation \tn % Row Count 13 (+ 3) % Row 3 \SetRowColor{white} Cellular Communication & Plant cells can emitt chemicals to communicate with neighbouring cells. this can tell the cell to: grow, freeze, die etc \tn % Row Count 18 (+ 5) \hhline{>{\arrayrulecolor{DarkBackground}}--} \SetRowColor{LightBackground} \mymulticolumn{2}{x{5.377cm}}{A secondary metabolic is a chemical produced by a plant which is not directly linked to the primary functions of the plant.} \tn \hhline{>{\arrayrulecolor{DarkBackground}}--} \end{tabularx} \par\addvspace{1.3em} \begin{tabularx}{5.377cm}{X} \SetRowColor{DarkBackground} \mymulticolumn{1}{x{5.377cm}}{\bf\textcolor{white}{What is Malaria}} \tn % Row 0 \SetRowColor{LightBackground} \mymulticolumn{1}{x{5.377cm}}{} \tn % Row Count 0 (+ 0) \hhline{>{\arrayrulecolor{DarkBackground}}-} \SetRowColor{LightBackground} \mymulticolumn{1}{x{5.377cm}}{Malaria is caused when a anopheline mosquito injects Plasmodium sporozoites into a victim. The bacteria travels through the bloodstream to the liver. In the liver the parasite multiplies for 7-10 days. when the infected liver ruptures it releases the parasite into the blood stream. they feed on important cell components. the bacteria is also called mrozoites.} \tn \hhline{>{\arrayrulecolor{DarkBackground}}-} \end{tabularx} \par\addvspace{1.3em} \begin{tabularx}{5.377cm}{x{2.4885 cm} x{2.4885 cm} } \SetRowColor{DarkBackground} \mymulticolumn{2}{x{5.377cm}}{\bf\textcolor{white}{Plant Medicines - Origins}} \tn % Row 0 \SetRowColor{LightBackground} Morphine (1804) & From: Dried Poppy Resin \{\{nl\}\} By: Friedrich W. Sertürner \{\{nl\}\} Use: Moderate-Severe pain \tn % Row Count 5 (+ 5) % Row 1 \SetRowColor{white} Quinine\{\{nl\}\} (1820) & From: Cinchona Bark \{\{nl\}\} By: Pelletier+Caventou \{\{nl\}\} Use: Malarial fevers \tn % Row Count 9 (+ 4) % Row 2 \SetRowColor{LightBackground} Colchicine\{\{nl\}\} (1820) & From: Autumn Crocus \{\{nl\}\} By: Pelletier+Caventou \{\{nl\}\} Use: Gout \tn % Row Count 13 (+ 4) % Row 3 \SetRowColor{white} Caffeine\{\{nl\}\} (1821) & From: Various Sources \{\{nl\}\} Friedrich F. Runge \{\{nl\}\} Use: Drowsiness \tn % Row Count 17 (+ 4) % Row 4 \SetRowColor{LightBackground} Atropine\{\{nl\}\} (1831) & From: Bellaonna \{\{nl\}\} By: Mein \{\{nl\}\} Use: Dilation of the pupil \tn % Row Count 21 (+ 4) % Row 5 \SetRowColor{white} Salicylic Acid\{\{nl\}\} (1838) & From: Weeping Willow \{\{nl\}\} By: Rafaelle Piria, Felix Hoffman \{\{nl\}\} Use: Aspirin \tn % Row Count 26 (+ 5) % Row 6 \SetRowColor{LightBackground} Cocaine\{\{nl\}\} (1860) & From: Coca Leaves \{\{nl\}\} By: Albert Neimann \{\{nl\}\} Use: N/A (too addictive) \tn % Row Count 30 (+ 4) \end{tabularx} \par\addvspace{1.3em} \vfill \columnbreak \begin{tabularx}{5.377cm}{x{2.4885 cm} x{2.4885 cm} } \SetRowColor{DarkBackground} \mymulticolumn{2}{x{5.377cm}}{\bf\textcolor{white}{Plant Medicines - Origins (cont)}} \tn % Row 7 \SetRowColor{LightBackground} Ephedrine\{\{nl\}\} (1887) & From: Ma Huang \{\{nl\}\} By: Nagai Nagayoshi \{\{nl\}\} Use: Asthma \tn % Row Count 3 (+ 3) % Row 8 \SetRowColor{white} L-DOPA\{\{nl\}\} (1914) & From: Broad Bean \{\{nl\}\} By: Marcus Guggunheim \{\{nl\}\} Use: Parkinson's \tn % Row Count 7 (+ 4) % Row 9 \SetRowColor{LightBackground} Cardiac Glycosides\{\{nl\}\} Digoxin \{\{nl\}\} (1930) & From: Foxglove \{\{nl\}\} By: Sydney Smith \{\{nl\}\} Use: Congestive Heart Failure \tn % Row Count 11 (+ 4) % Row 10 \SetRowColor{white} Warfarin \{\{nl\}\} (1948) & From: Mouldy Sweet Clover \{\{nl\}\}By: Karl Link\{\{nl\}\} Use: Anticoagulant \tn % Row Count 15 (+ 4) % Row 11 \SetRowColor{LightBackground} Paclitaxel \{\{nl\}\} (1967) & From: Pacific Yew \{\{nl\}\} By: US Cancer Institute\{\{nl\}\} Use: Anticancer \tn % Row Count 19 (+ 4) \hhline{>{\arrayrulecolor{DarkBackground}}--} \end{tabularx} \par\addvspace{1.3em} \begin{tabularx}{5.377cm}{X} \SetRowColor{DarkBackground} \mymulticolumn{1}{x{5.377cm}}{\bf\textcolor{white}{Youyou Tu}} \tn \SetRowColor{white} \mymulticolumn{1}{x{5.377cm}}{Youyou Tu led a group of researchers during Project 523. they isolated constituents from over 2000 herbal remedies and tested in on mice. they found that an extract from the qianghao plant proved effective. However, they struggled to replicate the tests. however, they found an ancient text which recommended that qinghao must be steeped in room temperature, and not hot water, to cure fevers. Youyou Tu developed a cold extraction method using water, alcohol and ethyl.% Row Count 10 (+ 10) } \tn \hhline{>{\arrayrulecolor{DarkBackground}}-} \end{tabularx} \par\addvspace{1.3em} % That's all folks \end{multicols*} \end{document}