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% Document Info
\author{nagabi}
\pdfinfo{
  /Title (endocrino-i-diabetes-mellitus-2.pdf)
  /Creator (Cheatography)
  /Author (nagabi)
  /Subject (Endocrino I: Diabetes Mellitus 2 Cheat Sheet)
}

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    {\parbox{\dimexpr\textwidth-2\fboxsep\relax}{\noindent
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\begin{tabulary}{11cm}{L}
    \vspace{-2pt}\large{\bf{\textcolor{DarkBackground}{\textrm{Endocrino I: Diabetes Mellitus 2 Cheat Sheet}}}} \\
    \normalsize{by \textcolor{DarkBackground}{nagabi} via \textcolor{DarkBackground}{\uline{cheatography.com/196758/cs/41387/}}}
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\noindent
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  \mymulticolumn{2}{p{5.377cm}}{\bf\textcolor{white}{Cheatographer}}  \\
  \vspace{-2pt}nagabi \\
  \uline{cheatography.com/nagabi} \\
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  \mymulticolumn{1}{p{5.377cm}}{\bf\textcolor{white}{Cheat Sheet}}  \\
   \vspace{-2pt}Not Yet Published.\\
   Updated 22nd November, 2023.\\
   Page {\thepage} of \pageref{LastPage}.
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  Measure your website readability!\\
  www.readability-score.com
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\begin{document}
\raggedright
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% from this page to resize cheat sheet text:
% www.emerson.emory.edu/services/latex/latex_169.html
\footnotesize % Small font.

\begin{multicols*}{2}

\begin{tabularx}{8.4cm}{X}
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\mymulticolumn{1}{x{8.4cm}}{\bf\textcolor{white}{Conceito}}  \tn
\SetRowColor{white}
\mymulticolumn{1}{x{8.4cm}}{Distúrbio metabólico em que ocorre um constante estado de {\bf{hiperglicemia permanente}} devido uma {\bf{resistência à insulina}}.\{\{nl\}\}- DM1 acomete cerca de {\bf{80\% dos pacientes}} com algum tipo de diabetes\{\{nl\}\}- costuma acometer paciente a partir de {\bf{50-60 anos}}.% Row Count 6 (+ 6)
} \tn 
\hhline{>{\arrayrulecolor{DarkBackground}}-}
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\par\addvspace{1.3em}

\begin{tabularx}{8.4cm}{X}
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\mymulticolumn{1}{x{8.4cm}}{\bf\textcolor{white}{Fatores de Risco}}  \tn
% Row 0
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\mymulticolumn{1}{x{8.4cm}}{{\bf{Síndrome Metabólica }}} \tn 
% Row Count 1 (+ 1)
% Row 1
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\mymulticolumn{1}{x{8.4cm}}{Obesidade} \tn 
% Row Count 2 (+ 1)
% Row 2
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\mymulticolumn{1}{x{8.4cm}}{Sedentarismo} \tn 
% Row Count 3 (+ 1)
% Row 3
\SetRowColor{white}
\mymulticolumn{1}{x{8.4cm}}{Dislipdemia} \tn 
% Row Count 4 (+ 1)
% Row 4
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\mymulticolumn{1}{x{8.4cm}}{Histórico Familiar} \tn 
% Row Count 5 (+ 1)
% Row 5
\SetRowColor{white}
\mymulticolumn{1}{x{8.4cm}}{Síndrome do Ovário Policístico (SOP)} \tn 
% Row Count 6 (+ 1)
\hhline{>{\arrayrulecolor{DarkBackground}}-}
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\par\addvspace{1.3em}

\begin{tabularx}{8.4cm}{X}
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\mymulticolumn{1}{x{8.4cm}}{\bf\textcolor{white}{Fisiopatologia}}  \tn
\SetRowColor{white}
\mymulticolumn{1}{x{8.4cm}}{A fisiopatologia da DM2 é multifatorial e subdividida em etapas, pois se trata de uma doença crônica e progressiva.\{\{nl\}\}1){\bf{ Resistência Insulínica}} - falha da proteína GLUT em transportar a glicose para o meio intracelular\{\{nl\}\} 2) {\bf{Glicogenolise Excessiva}} - produção excessiva de insulina estimula quebra excessiva de lipídios \{\{nl\}\} 3){\bf{ Insuficiência Pancreática}} - esgotamento das células β-pancreáticas% Row Count 9 (+ 9)
} \tn 
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\mymulticolumn{1}{x{8.4cm}}{\bf\textcolor{white}{Manifestações Clínicas}}  \tn
% Row 0
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\mymulticolumn{1}{x{8.4cm}}{{\bf{Polidipsia}} aka sede anormal ou excessiva} \tn 
% Row Count 1 (+ 1)
% Row 1
\SetRowColor{white}
\mymulticolumn{1}{x{8.4cm}}{{\bf{Poliúria}} ou {\bf{Noctúria}} aka urinação excessiva em geral ou à noite} \tn 
% Row Count 3 (+ 2)
% Row 2
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\mymulticolumn{1}{x{8.4cm}}{{\bf{Polifagia}} aka fome excessiva} \tn 
% Row Count 4 (+ 1)
% Row 3
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\mymulticolumn{1}{x{8.4cm}}{{\bf{Perda de Peso Ponderal}} aka perda de peso sem motivo aparente} \tn 
% Row Count 6 (+ 2)
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\begin{tabularx}{8.4cm}{x{0.988 cm} x{3.344 cm} x{3.268 cm} }
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\mymulticolumn{3}{x{8.4cm}}{\bf\textcolor{white}{Diagnóstico}}  \tn
% Row 0
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\mymulticolumn{3}{x{8.4cm}}{Clínico} \tn 
% Row Count 1 (+ 1)
% Row 1
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\seqsplit{Laboratorial} & {\bf{Glicemia em Jejum\{\{nl\}\}TOTG\{\{nl\}\}Glicemia Ocasional\{\{nl\}\}Hemoglobina Glicada}} & {\bf{≥ 126\{\{nl\}\}≥ 200\{\{nl\}\}≥ 200 + sintomas\{\{nl\}\}≥ 6,5}} \tn 
% Row Count 6 (+ 5)
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\mymulticolumn{3}{x{8.4cm}}{Deve-se levar em conta que todos os exames laboratoriais, exceto a hemoglobina glicada, necessitam de {\bf{duas aferições}} em períodos separados para fechar o diagnóstico.}  \tn 
\hhline{>{\arrayrulecolor{DarkBackground}}---}
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\mymulticolumn{1}{x{8.4cm}}{\bf\textcolor{white}{Diagnóstico Diferencial}}  \tn
% Row 0
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\mymulticolumn{1}{x{8.4cm}}{Síndrome Metabólica - conjunto de fatores de risco, sendo eles HAS, hiperglicemia, obesidade, sedentarismo e dislipdemia} \tn 
% Row Count 3 (+ 3)
% Row 1
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\mymulticolumn{1}{x{8.4cm}}{(MODY) - DM familiar autossômico-dominante} \tn 
% Row Count 4 (+ 1)
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\mymulticolumn{2}{x{8.4cm}}{\bf\textcolor{white}{Complicações}}  \tn
% Row 0
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Agudas & {\bf{Cetoacidose Diabética (CAD)\{\{nl\}\}Estado Hiperglicêmico Hiperosmolar (EHH)}} \tn 
% Row Count 3 (+ 3)
% Row 1
\SetRowColor{white}
\seqsplit{Crônicas} & {\bf{Cardiopatias }}(ex: infarto e AVE)\{\{nl\}\}{\bf{Nefropatia\{\{nl\}\}Neuropatia Periférica\{\{nl\}\}Retinopatia\{\{nl\}\} Amputação}} (por lesões e/ou necrose tecidual) \tn 
% Row Count 8 (+ 5)
\hhline{>{\arrayrulecolor{DarkBackground}}--}
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\begin{tabularx}{8.4cm}{x{1.9 cm} x{2.888 cm} x{2.812 cm} }
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\mymulticolumn{3}{x{8.4cm}}{\bf\textcolor{white}{Tratamento}}  \tn
% Row 0
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\mymulticolumn{3}{x{8.4cm}}{Mudanças no Estilo de Vida (MEV's)} \tn 
% Row Count 1 (+ 1)
% Row 1
\SetRowColor{white}
\seqsplit{Hipoglicemiantes} Orais (HO) & HbA1c \textless{} 7,5\%\{\{nl\}\}HbA1c \textgreater{} 7,5\{\{nl\}\}HbA1c \textgreater{} 9\% + sintomas & Monoterapia\{\{nl\}\}Terapia Dupla ou terapia baseada em insulina caso apresente sintomas\{\{nl\}\} Terapia baseada em insulina com ou sem metformina \tn 
% Row Count 12 (+ 11)
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Insulina Exógena & 0,5 a 2 UI/kg/dia &  \tn 
% Row Count 14 (+ 2)
\hhline{>{\arrayrulecolor{DarkBackground}}---}
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\mymulticolumn{3}{x{8.4cm}}{Monoterapia: Metformina \newline Terapia Dupla: Metformina + HO \newline Terapia Tripla: Metformina + 2HO* \newline Terapia Quadrupla: Metformina + 3HO* \newline {\emph{* Intensificação da Terapia caso hemoglobina glicada (HbA1c) permaneça acima da meta após 3 meses no tratamento}}}  \tn 
\hhline{>{\arrayrulecolor{DarkBackground}}---}
\end{tabularx}
\par\addvspace{1.3em}


% That's all folks
\end{multicols*}

\end{document}