\documentclass[10pt,a4paper]{article}

% Packages
\usepackage{fancyhdr}           % For header and footer
\usepackage{multicol}           % Allows multicols in tables
\usepackage{tabularx}           % Intelligent column widths
\usepackage{tabulary}           % Used in header and footer
\usepackage{hhline}             % Border under tables
\usepackage{graphicx}           % For images
\usepackage{xcolor}             % For hex colours
%\usepackage[utf8x]{inputenc}    % For unicode character support
\usepackage[T1]{fontenc}        % Without this we get weird character replacements
\usepackage{colortbl}           % For coloured tables
\usepackage{setspace}           % For line height
\usepackage{lastpage}           % Needed for total page number
\usepackage{seqsplit}           % Splits long words.
%\usepackage{opensans}          % Can't make this work so far. Shame. Would be lovely.
\usepackage[normalem]{ulem}     % For underlining links
% Most of the following are not required for the majority
% of cheat sheets but are needed for some symbol support.
\usepackage{amsmath}            % Symbols
\usepackage{MnSymbol}           % Symbols
\usepackage{wasysym}            % Symbols
%\usepackage[english,german,french,spanish,italian]{babel}              % Languages

% Document Info
\author{Morghay123}
\pdfinfo{
  /Title (the-viral-world-l2.pdf)
  /Creator (Cheatography)
  /Author (Morghay123)
  /Subject (The Viral World-L2 Cheat Sheet)
}

% Lengths and widths
\addtolength{\textwidth}{6cm}
\addtolength{\textheight}{-1cm}
\addtolength{\hoffset}{-3cm}
\addtolength{\voffset}{-2cm}
\setlength{\tabcolsep}{0.2cm} % Space between columns
\setlength{\headsep}{-12pt} % Reduce space between header and content
\setlength{\headheight}{85pt} % If less, LaTeX automatically increases it
\renewcommand{\footrulewidth}{0pt} % Remove footer line
\renewcommand{\headrulewidth}{0pt} % Remove header line
\renewcommand{\seqinsert}{\ifmmode\allowbreak\else\-\fi} % Hyphens in seqsplit
% This two commands together give roughly
% the right line height in the tables
\renewcommand{\arraystretch}{1.3}
\onehalfspacing

% Commands
\newcommand{\SetRowColor}[1]{\noalign{\gdef\RowColorName{#1}}\rowcolor{\RowColorName}} % Shortcut for row colour
\newcommand{\mymulticolumn}[3]{\multicolumn{#1}{>{\columncolor{\RowColorName}}#2}{#3}} % For coloured multi-cols
\newcolumntype{x}[1]{>{\raggedright}p{#1}} % New column types for ragged-right paragraph columns
\newcommand{\tn}{\tabularnewline} % Required as custom column type in use

% Font and Colours
\definecolor{HeadBackground}{HTML}{333333}
\definecolor{FootBackground}{HTML}{666666}
\definecolor{TextColor}{HTML}{333333}
\definecolor{DarkBackground}{HTML}{0E7806}
\definecolor{LightBackground}{HTML}{F7FAF7}
\renewcommand{\familydefault}{\sfdefault}
\color{TextColor}

% Header and Footer
\pagestyle{fancy}
\fancyhead{} % Set header to blank
\fancyfoot{} % Set footer to blank
\fancyhead[L]{
\noindent
\begin{multicols}{3}
\begin{tabulary}{5.8cm}{C}
    \SetRowColor{DarkBackground}
    \vspace{-7pt}
    {\parbox{\dimexpr\textwidth-2\fboxsep\relax}{\noindent
        \hspace*{-6pt}\includegraphics[width=5.8cm]{/web/www.cheatography.com/public/images/cheatography_logo.pdf}}
    }
\end{tabulary}
\columnbreak
\begin{tabulary}{11cm}{L}
    \vspace{-2pt}\large{\bf{\textcolor{DarkBackground}{\textrm{The Viral World-L2 Cheat Sheet}}}} \\
    \normalsize{by \textcolor{DarkBackground}{Morghay123} via \textcolor{DarkBackground}{\uline{cheatography.com/53154/cs/14540/}}}
\end{tabulary}
\end{multicols}}

\fancyfoot[L]{ \footnotesize
\noindent
\begin{multicols}{3}
\begin{tabulary}{5.8cm}{LL}
  \SetRowColor{FootBackground}
  \mymulticolumn{2}{p{5.377cm}}{\bf\textcolor{white}{Cheatographer}}  \\
  \vspace{-2pt}Morghay123 \\
  \uline{cheatography.com/morghay123} \\
  \end{tabulary}
\vfill
\columnbreak
\begin{tabulary}{5.8cm}{L}
  \SetRowColor{FootBackground}
  \mymulticolumn{1}{p{5.377cm}}{\bf\textcolor{white}{Cheat Sheet}}  \\
   \vspace{-2pt}Not Yet Published.\\
   Updated 30th January, 2018.\\
   Page {\thepage} of \pageref{LastPage}.
\end{tabulary}
\vfill
\columnbreak
\begin{tabulary}{5.8cm}{L}
  \SetRowColor{FootBackground}
  \mymulticolumn{1}{p{5.377cm}}{\bf\textcolor{white}{Sponsor}}  \\
  \SetRowColor{white}
  \vspace{-5pt}
  %\includegraphics[width=48px,height=48px]{dave.jpeg}
  Measure your website readability!\\
  www.readability-score.com
\end{tabulary}
\end{multicols}}




\begin{document}
\raggedright
\raggedcolumns

% Set font size to small. Switch to any value
% from this page to resize cheat sheet text:
% www.emerson.emory.edu/services/latex/latex_169.html
\footnotesize % Small font.

\begin{multicols*}{2}

\begin{tabularx}{8.4cm}{p{0.8 cm} p{0.8 cm} }
\SetRowColor{DarkBackground}
\mymulticolumn{2}{x{8.4cm}}{\bf\textcolor{white}{Common Features of a Virus}}  \tn
% Row 0
\SetRowColor{LightBackground}
\mymulticolumn{2}{x{8.4cm}}{{\bf{1. Genome}}} \tn 
% Row Count 1 (+ 1)
% Row 1
\SetRowColor{white}
\mymulticolumn{2}{x{8.4cm}}{- Could be ssDNA, dsDNA, dsRNA, ssRNA} \tn 
% Row Count 2 (+ 1)
% Row 2
\SetRowColor{LightBackground}
\mymulticolumn{2}{x{8.4cm}}{- Viruses are particles and there is a question about if they are living or non-living ({\emph{need a host cell for reproduction}})} \tn 
% Row Count 5 (+ 3)
% Row 3
\SetRowColor{white}
\mymulticolumn{2}{x{8.4cm}}{- Our genome is DNA, viruses can harm different types} \tn 
% Row Count 7 (+ 2)
% Row 4
\SetRowColor{LightBackground}
\mymulticolumn{2}{x{8.4cm}}{-{}-\textgreater{} Always a nucleic acid} \tn 
% Row Count 8 (+ 1)
% Row 5
\SetRowColor{white}
\mymulticolumn{2}{x{8.4cm}}{{\emph{What does the genome do?}}} \tn 
% Row Count 9 (+ 1)
% Row 6
\SetRowColor{LightBackground}
\mymulticolumn{2}{x{8.4cm}}{- Codes for proteins to run the virus\{\{nl\}\}-{}-\textgreater{} genome is the smallest} \tn 
% Row Count 11 (+ 2)
% Row 7
\SetRowColor{white}
\mymulticolumn{2}{x{8.4cm}}{{\bf{2. Capsid}}} \tn 
% Row Count 12 (+ 1)
% Row 8
\SetRowColor{LightBackground}
\mymulticolumn{2}{x{8.4cm}}{- a virally coded protein coat, shell, or sheath that surrounds the nucleic acid} \tn 
% Row Count 14 (+ 2)
% Row 9
\SetRowColor{white}
\mymulticolumn{2}{x{8.4cm}}{Capsid= protein coat surrounding genome} \tn 
% Row Count 15 (+ 1)
% Row 10
\SetRowColor{LightBackground}
\mymulticolumn{2}{x{8.4cm}}{Protects genome from breakdown and facilitates entry} \tn 
% Row Count 17 (+ 2)
% Row 11
\SetRowColor{white}
\mymulticolumn{2}{x{8.4cm}}{{\bf{Some viruses have membrane}}} \tn 
% Row Count 18 (+ 1)
\hhline{>{\arrayrulecolor{DarkBackground}}--}
\end{tabularx}
\par\addvspace{1.3em}

\begin{tabularx}{8.4cm}{p{0.8 cm} p{0.8 cm} }
\SetRowColor{DarkBackground}
\mymulticolumn{2}{x{8.4cm}}{\bf\textcolor{white}{Virus Diversity}}  \tn
% Row 0
\SetRowColor{LightBackground}
\mymulticolumn{2}{x{8.4cm}}{{\bf{Rod}}\{\{nl\}\}- RNA\{\{nl\}\}- Capsomere of capsid\{\{nl\}\}ex:{\emph{ Tobacco mosaic virus}}} \tn 
% Row Count 2 (+ 2)
% Row 1
\SetRowColor{white}
\mymulticolumn{2}{x{8.4cm}}{Simplest virus} \tn 
% Row Count 3 (+ 1)
% Row 2
\SetRowColor{LightBackground}
\mymulticolumn{2}{x{8.4cm}}{{\bf{Adenoviruses}}\{\{nl\}\}- Capsomere\{\{nl\}\}- DNA\{\{nl\}\}- Glycoprotein} \tn 
% Row Count 5 (+ 2)
% Row 3
\SetRowColor{white}
\mymulticolumn{2}{x{8.4cm}}{- Cause us to get sick} \tn 
% Row Count 6 (+ 1)
% Row 4
\SetRowColor{LightBackground}
\mymulticolumn{2}{x{8.4cm}}{{\bf{Circle Virus}}\{\{nl\}\}- Membranous envelope\{\{nl\}\}- RNA\{\{nl\}\}- Glycoprotein\{\{nl\}\}- Capsid\{\{nl\}\}ex: {\emph{Influenza Viruses}}} \tn 
% Row Count 9 (+ 3)
% Row 5
\SetRowColor{white}
\mymulticolumn{2}{x{8.4cm}}{- Affect animals= have membrane around capsid} \tn 
% Row Count 10 (+ 1)
% Row 6
\SetRowColor{LightBackground}
\mymulticolumn{2}{x{8.4cm}}{{\bf{Moon Landing Shaped One}}\{\{nl\}\}- DNA\{\{nl\}\}- Tail sheath\{\{nl\}\}- Head\{\{nl\}\}- Tail fiber\{\{nl\}\}ex: {\emph{Bacteriophage T4}}} \tn 
% Row Count 13 (+ 3)
% Row 7
\SetRowColor{white}
\mymulticolumn{2}{x{8.4cm}}{- Phages are viruses that collect bacteria\{\{nl\}\}-{}-\textgreater{} bacteriophages} \tn 
% Row Count 15 (+ 2)
\hhline{>{\arrayrulecolor{DarkBackground}}--}
\end{tabularx}
\par\addvspace{1.3em}

\begin{tabularx}{8.4cm}{p{0.8 cm} p{0.8 cm} }
\SetRowColor{DarkBackground}
\mymulticolumn{2}{x{8.4cm}}{\bf\textcolor{white}{Genome of HIV Virus}}  \tn
% Row 0
\SetRowColor{LightBackground}
\mymulticolumn{2}{x{8.4cm}}{{\bf{gag}}} \tn 
% Row Count 1 (+ 1)
% Row 1
\SetRowColor{white}
\mymulticolumn{2}{x{8.4cm}}{Components of capsid\{\{nl\}\}- Matrix\{\{nl\}\}- Capsid\{\{nl\}\}- Nucleocapsid\{\{nl\}\}- Vpr-binding protein} \tn 
% Row Count 3 (+ 2)
% Row 2
\SetRowColor{LightBackground}
\mymulticolumn{2}{x{8.4cm}}{{\bf{pol}}} \tn 
% Row Count 4 (+ 1)
% Row 3
\SetRowColor{white}
\mymulticolumn{2}{x{8.4cm}}{Proteins required for reverse transcription and integration into host DNA\{\{nl\}\}- Protease\{\{nl\}\}- Reverse transcriptase\{\{nl\}\}- Integrase} \tn 
% Row Count 7 (+ 3)
% Row 4
\SetRowColor{LightBackground}
\mymulticolumn{2}{x{8.4cm}}{{\bf{env}}} \tn 
% Row Count 8 (+ 1)
% Row 5
\SetRowColor{white}
\mymulticolumn{2}{x{8.4cm}}{Surface Proteins\{\{nl\}\}- Surface glycoprotein\{\{nl\}\}- Transmembrane glycoprotein} \tn 
% Row Count 10 (+ 2)
% Row 6
\SetRowColor{LightBackground}
\mymulticolumn{2}{x{8.4cm}}{{\bf{Infection Cycle}}} \tn 
% Row Count 11 (+ 1)
% Row 7
\SetRowColor{white}
\mymulticolumn{2}{x{8.4cm}}{Infects human white blood cells\{\{nl\}\}- Immune System deficiency} \tn 
% Row Count 13 (+ 2)
\hhline{>{\arrayrulecolor{DarkBackground}}--}
\end{tabularx}
\par\addvspace{1.3em}

\begin{tabularx}{8.4cm}{X}
\SetRowColor{DarkBackground}
\mymulticolumn{1}{x{8.4cm}}{\bf\textcolor{white}{Viral Genome Classification}}  \tn
% Row 0
\SetRowColor{LightBackground}
\mymulticolumn{1}{x{8.4cm}}{{\bf{Virus Classes}}} \tn 
% Row Count 1 (+ 1)
% Row 1
\SetRowColor{white}
\mymulticolumn{1}{x{8.4cm}}{Class 1\{\{nl\}\}\textgreater{} Double-Stranded DNA (+)} \tn 
% Row Count 2 (+ 1)
% Row 2
\SetRowColor{LightBackground}
\mymulticolumn{1}{x{8.4cm}}{Class 4\{\{nl\}\}\textgreater{} Single-Stranded RNA (+)} \tn 
% Row Count 3 (+ 1)
% Row 3
\SetRowColor{white}
\mymulticolumn{1}{x{8.4cm}}{Class 5\{\{nl\}\}\textgreater{} Single-Stranded RNA (-)} \tn 
% Row Count 4 (+ 1)
% Row 4
\SetRowColor{LightBackground}
\mymulticolumn{1}{x{8.4cm}}{Class 6\{\{nl\}\}\textgreater{} Single-Stranded RNA (+)\{\{nl\}\}-{}-\textgreater{} SPECIAL "retro virus"} \tn 
% Row Count 6 (+ 2)
% Row 5
\SetRowColor{white}
\mymulticolumn{1}{x{8.4cm}}{{\bf{Use genome (DNA and RNA) of virus to classify the bacteria}}} \tn 
% Row Count 8 (+ 2)
% Row 6
\SetRowColor{LightBackground}
\mymulticolumn{1}{x{8.4cm}}{Must ask:\{\{nl\}\}- How is genome made? Poly. used?\{\{nl\}\}- How is the mRNA made? Poly. used?\{\{nl\}\}- Are the poly derived from the host or virus genome?} \tn 
% Row Count 11 (+ 3)
% Row 7
\SetRowColor{white}
\mymulticolumn{1}{x{8.4cm}}{{\bf{D.S. DNA Viruses}}\{\{nl\}\}- Genome: D.S. DNA (what comes into host)\{\{nl\}\}-{}-\textgreater{} DdDp needed for virus (host has this)\{\{nl\}\}- mRNA: D.S. DNA -{}-\textgreater{} mRNA\{\{nl\}\}-{}-\textgreater{} DdRp (already has this in host)} \tn 
% Row Count 15 (+ 4)
% Row 8
\SetRowColor{LightBackground}
\mymulticolumn{1}{x{8.4cm}}{{\bf{RNA}}\{\{nl\}\}- ss(+) RNA virus=\textgreater{} many bacteria phages\{\{nl\}\}- Genome:ss(+) RNA=\textgreater{}template(-)RNA=\textgreater{}(+)RNA\{\{nl\}\}-{}-\textgreater{} RdRp: has to be virally encoded. Does not have to be carried in by virus since (+) RNA can be read by mRNA} \tn 
% Row Count 20 (+ 5)
% Row 9
\SetRowColor{white}
\mymulticolumn{1}{x{8.4cm}}{{\bf{ss(-)RNA=\textgreater{}(+)ssRNA=\textgreater{}(-)ssRNA}}\{\{nl\}\}- RdRp: has to be brought in by virus} \tn 
% Row Count 22 (+ 2)
% Row 10
\SetRowColor{LightBackground}
\mymulticolumn{1}{x{8.4cm}}{{\bf{Retrovirus}}\{\{nl\}\}- even though they are (+) RNA they dont follow pattern.\{\{nl\}\}- Be integrated into host genome and replicate the provirus with it\{\{nl\}\}{\emph{(+)ssRNA=\textgreater{}DNA=\textgreater{}Protein}}\{\{nl\}\}\textgreater{} Reverse transcriptase carried by virus (after +ssRNA)\{\{nl\}\}\textgreater{} DNA integrated intermediate host genome} \tn 
% Row Count 28 (+ 6)
\hhline{>{\arrayrulecolor{DarkBackground}}-}
\end{tabularx}
\par\addvspace{1.3em}

\begin{tabularx}{8.4cm}{X}
\SetRowColor{DarkBackground}
\mymulticolumn{1}{x{8.4cm}}{\bf\textcolor{white}{Influenza Virus}}  \tn
% Row 0
\SetRowColor{LightBackground}
\mymulticolumn{1}{x{8.4cm}}{{\emph{H and N}}\{\{nl\}\}\textgreater{} glycoproteins on the surface of the glycoprotein\{\{nl\}\}\textgreater{} HA- 16 common variants of the protein\{\{nl\}\}\textgreater{} NA- 9 common variants of the protein} \tn 
% Row Count 4 (+ 4)
% Row 1
\SetRowColor{white}
\mymulticolumn{1}{x{8.4cm}}{(-) ssRNA virus with a genome with 8 segments} \tn 
% Row Count 5 (+ 1)
% Row 2
\SetRowColor{LightBackground}
\mymulticolumn{1}{x{8.4cm}}{\textgreater{} Newly released influenza viruses will be genetically heterogenous enabling a high rate of evolution} \tn 
% Row Count 8 (+ 3)
% Row 3
\SetRowColor{white}
\mymulticolumn{1}{x{8.4cm}}{\textgreater{} HA and NA may not be detectable by our immune system due to {\bf{antigenic drift}}} \tn 
% Row Count 10 (+ 2)
% Row 4
\SetRowColor{LightBackground}
\mymulticolumn{1}{x{8.4cm}}{-{}-\textgreater{} Enters via fusion\{\{nl\}\}-{}-\textgreater{} Carries own polyperase\{\{nl\}\}-{}-{}-\textgreater{} doesnt have proofreading mechanism} \tn 
% Row Count 12 (+ 2)
% Row 5
\SetRowColor{white}
\mymulticolumn{1}{x{8.4cm}}{{\emph{high mutation rate}}} \tn 
% Row Count 13 (+ 1)
% Row 6
\SetRowColor{LightBackground}
\mymulticolumn{1}{x{8.4cm}}{Viral reassortment may lead to {\bf{antigenic shift}} (a new influenza subtype)\{\{nl\}\}- different strains for humans and animals} \tn 
% Row Count 16 (+ 3)
\hhline{>{\arrayrulecolor{DarkBackground}}-}
\end{tabularx}
\par\addvspace{1.3em}

\begin{tabularx}{8.4cm}{p{0.8 cm} p{0.8 cm} }
\SetRowColor{DarkBackground}
\mymulticolumn{2}{x{8.4cm}}{\bf\textcolor{white}{Basic Viral Infection Cycle}}  \tn
% Row 0
\SetRowColor{LightBackground}
\mymulticolumn{2}{x{8.4cm}}{1. Entry and uncoading} \tn 
% Row Count 1 (+ 1)
% Row 1
\SetRowColor{white}
\mymulticolumn{2}{x{8.4cm}}{2. Replication} \tn 
% Row Count 2 (+ 1)
% Row 2
\SetRowColor{LightBackground}
\mymulticolumn{2}{x{8.4cm}}{3. Transcription and manufacture of capsid proteins} \tn 
% Row Count 4 (+ 2)
% Row 3
\SetRowColor{white}
\mymulticolumn{2}{x{8.4cm}}{4. Self-assembly of new virus particles and their exit from the cell} \tn 
% Row Count 6 (+ 2)
% Row 4
\SetRowColor{LightBackground}
\mymulticolumn{2}{x{8.4cm}}{{\emph{Phages are the best understood of all viruses}}} \tn 
% Row Count 7 (+ 1)
% Row 5
\SetRowColor{white}
\mymulticolumn{2}{x{8.4cm}}{Entry: Mechanism to the virus that attaches to the host cell and into the cytoplasm} \tn 
% Row Count 9 (+ 2)
% Row 6
\SetRowColor{LightBackground}
\mymulticolumn{2}{x{8.4cm}}{- Viruses that have membranes can be receptor mediated (*endocytosis)} \tn 
% Row Count 11 (+ 2)
% Row 7
\SetRowColor{white}
\mymulticolumn{2}{x{8.4cm}}{- Bacteria phage injection genome\{\{nl\}\}-{}-\textgreater{} can be replicated, always ends up in cell bursting} \tn 
% Row Count 13 (+ 2)
% Row 8
\SetRowColor{LightBackground}
\mymulticolumn{2}{x{8.4cm}}{Flu Virus= membrane fusion membranes fuse together and go into cell} \tn 
% Row Count 15 (+ 2)
% Row 9
\SetRowColor{white}
\mymulticolumn{2}{x{8.4cm}}{{\emph{Receptor-Mediated Mechanism}}} \tn 
% Row Count 16 (+ 1)
% Row 10
\SetRowColor{LightBackground}
\mymulticolumn{2}{x{8.4cm}}{{\emph{Replication}}= DNA replication. Every time a cell divides} \tn 
% Row Count 18 (+ 2)
% Row 11
\SetRowColor{white}
\mymulticolumn{2}{x{8.4cm}}{{\emph{Central Dogma}}\{\{nl\}\}-DNA\{\{nl\}\}-{}-Transcription ({\emph{DdRP RNA Polymerase}})\{\{nl\}\}-RNA\{\{nl\}\}-{}-Translation({\emph{Ribosomes, tRNA...Always sue ribosomes from the host}})\{\{nl\}\}-Protein} \tn 
% Row Count 22 (+ 4)
% Row 12
\SetRowColor{LightBackground}
\mymulticolumn{2}{x{8.4cm}}{{\emph{DdDp}} ==\textgreater{} DNA dependent DNA polymerase} \tn 
% Row Count 23 (+ 1)
\hhline{>{\arrayrulecolor{DarkBackground}}--}
\end{tabularx}
\par\addvspace{1.3em}


% That's all folks
\end{multicols*}

\end{document}