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\usepackage{seqsplit}           % Splits long words.
%\usepackage{opensans}          % Can't make this work so far. Shame. Would be lovely.
\usepackage[normalem]{ulem}     % For underlining links
% Most of the following are not required for the majority
% of cheat sheets but are needed for some symbol support.
\usepackage{amsmath}            % Symbols
\usepackage{MnSymbol}           % Symbols
\usepackage{wasysym}            % Symbols
%\usepackage[english,german,french,spanish,italian]{babel}              % Languages

% Document Info
\author{gracev (gracev21)}
\pdfinfo{
  /Title (microbial-control.pdf)
  /Creator (Cheatography)
  /Author (gracev (gracev21))
  /Subject (microbial control Cheat Sheet)
}

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% Header and Footer
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\fancyhead[L]{
\noindent
\begin{multicols}{3}
\begin{tabulary}{5.8cm}{C}
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    \vspace{-7pt}
    {\parbox{\dimexpr\textwidth-2\fboxsep\relax}{\noindent
        \hspace*{-6pt}\includegraphics[width=5.8cm]{/web/www.cheatography.com/public/images/cheatography_logo.pdf}}
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\columnbreak
\begin{tabulary}{11cm}{L}
    \vspace{-2pt}\large{\bf{\textcolor{DarkBackground}{\textrm{microbial control Cheat Sheet}}}} \\
    \normalsize{by \textcolor{DarkBackground}{gracev (gracev21)} via \textcolor{DarkBackground}{\uline{cheatography.com/168753/cs/35367/}}}
\end{tabulary}
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\fancyfoot[L]{ \footnotesize
\noindent
\begin{multicols}{3}
\begin{tabulary}{5.8cm}{LL}
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  \mymulticolumn{2}{p{5.377cm}}{\bf\textcolor{white}{Cheatographer}}  \\
  \vspace{-2pt}gracev (gracev21) \\
  \uline{cheatography.com/gracev21} \\
  \end{tabulary}
\vfill
\columnbreak
\begin{tabulary}{5.8cm}{L}
  \SetRowColor{FootBackground}
  \mymulticolumn{1}{p{5.377cm}}{\bf\textcolor{white}{Cheat Sheet}}  \\
   \vspace{-2pt}Published 9th November, 2022.\\
   Updated 9th November, 2022.\\
   Page {\thepage} of \pageref{LastPage}.
\end{tabulary}
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  \vspace{-5pt}
  %\includegraphics[width=48px,height=48px]{dave.jpeg}
  Measure your website readability!\\
  www.readability-score.com
\end{tabulary}
\end{multicols}}




\begin{document}
\raggedright
\raggedcolumns

% Set font size to small. Switch to any value
% from this page to resize cheat sheet text:
% www.emerson.emory.edu/services/latex/latex_169.html
\footnotesize % Small font.

\begin{multicols*}{3}

\begin{tabularx}{5.377cm}{x{1.34379 cm} x{3.63321 cm} }
\SetRowColor{DarkBackground}
\mymulticolumn{2}{x{5.377cm}}{\bf\textcolor{white}{terminology of microbe control}}  \tn
% Row 0
\SetRowColor{LightBackground}
\seqsplit{sterilization} & removal or destruction of ALL microbes in or on an object \tn 
% Row Count 2 (+ 2)
% Row 1
\SetRowColor{white}
sterilant & sterilizing agent \tn 
% Row Count 3 (+ 1)
% Row 2
\SetRowColor{LightBackground}
aseptic & an environment or procedure that is free of all pathogenic contaminants \tn 
% Row Count 6 (+ 3)
% Row 3
\SetRowColor{white}
sepsis & microbial contamination \tn 
% Row Count 7 (+ 1)
% Row 4
\SetRowColor{LightBackground}
\seqsplit{disinfection} & using physical or chemical agents to destroy microbes/viruses on NON LIVING surface \tn 
% Row Count 10 (+ 3)
% Row 5
\SetRowColor{white}
\seqsplit{antisepsis} & reduction of microbes on LIVING tissue \tn 
% Row Count 12 (+ 2)
% Row 6
\SetRowColor{LightBackground}
degerming & removing microbes by mechanical means (ex. washing hands with soap) \tn 
% Row Count 15 (+ 3)
% Row 7
\SetRowColor{white}
\seqsplit{sanitization} & removing pathogens from objects to meet public health standard \tn 
% Row Count 18 (+ 3)
% Row 8
\SetRowColor{LightBackground}
\seqsplit{pateurization} & use of heat to destroy pathogen \tn 
% Row Count 20 (+ 2)
% Row 9
\SetRowColor{white}
\seqsplit{-stasis/-static} & a chemical or physical agent PREVENTS microbial metabolism and growth \tn 
% Row Count 23 (+ 3)
% Row 10
\SetRowColor{LightBackground}
-cide/ cidal & agents that destroy or permanently inactivate a particular type of microbe \tn 
% Row Count 26 (+ 3)
\hhline{>{\arrayrulecolor{DarkBackground}}--}
\end{tabularx}
\par\addvspace{1.3em}

\begin{tabularx}{5.377cm}{x{1.9908 cm} x{2.9862 cm} }
\SetRowColor{DarkBackground}
\mymulticolumn{2}{x{5.377cm}}{\bf\textcolor{white}{physical microbe control}}  \tn
% Row 0
\SetRowColor{LightBackground}
heat sterilization & uses heat at specific time and temp. to denature and destroy cell membranes can be used to pasteurize, sterilize, sanitize and disinfect \tn 
% Row Count 6 (+ 6)
% Row 1
\SetRowColor{white}
moist heat (boiling) & kills vegetative bacterial pathogens, fungi, protozoa, and some virus \tn 
% Row Count 9 (+ 3)
% Row 2
\SetRowColor{LightBackground}
dry heat (pressure chamber) & most effective sterilization is when the steam penetrates the object \tn 
% Row Count 12 (+ 3)
% Row 3
\SetRowColor{white}
pasteurization & not sterilization kills pathogens \tn 
% Row Count 14 (+ 2)
% Row 4
\SetRowColor{LightBackground}
refrigeration and freeze & freeze - ice crystals puncture cell membranes \tn 
% Row Count 16 (+ 2)
% Row 5
\SetRowColor{white}
filtration (masks) & passing fluid through a sieve designed to trap particles (prevents airborne contamination by microbes) \tn 
% Row Count 21 (+ 5)
% Row 6
\SetRowColor{LightBackground}
X rays and gamma rays & kills microbes by creating oxygen radicals, breaking DNA, and ionizing. \tn 
% Row Count 24 (+ 3)
% Row 7
\SetRowColor{white}
ultraviolet light & nonionizing, kills microbes by being absorbed by DNA and creating mutations in DNA \tn 
% Row Count 28 (+ 4)
\hhline{>{\arrayrulecolor{DarkBackground}}--}
\end{tabularx}
\par\addvspace{1.3em}

\begin{tabularx}{5.377cm}{x{2.33919 cm} x{2.63781 cm} }
\SetRowColor{DarkBackground}
\mymulticolumn{2}{x{5.377cm}}{\bf\textcolor{white}{resistance to drugs}}  \tn
% Row 0
\SetRowColor{LightBackground}
cells can acquire resistance 2 ways & new mutations, acquiring genes on extra DNA \tn 
% Row Count 3 (+ 3)
% Row 1
\SetRowColor{white}
enzyme & destroys or deactivates drug \tn 
% Row Count 5 (+ 2)
% Row 2
\SetRowColor{LightBackground}
prevent entry & changes in structure to slow or stop entry of drug \tn 
% Row Count 8 (+ 3)
% Row 3
\SetRowColor{white}
alteration & alter target to the drug to affect binding \tn 
% Row Count 10 (+ 2)
% Row 4
\SetRowColor{LightBackground}
metabolic chemistry & resistant drugs can alter or abandon sensitive metabolic steps \tn 
% Row Count 13 (+ 3)
% Row 5
\SetRowColor{white}
resistance pumps & cell pumps antimicrobial out of cell \tn 
% Row Count 15 (+ 2)
% Row 6
\SetRowColor{LightBackground}
unusual proteins & resistance to fluoroquinolone drugs \tn 
% Row Count 17 (+ 2)
% Row 7
\SetRowColor{white}
cross resistance & resistance to one antimicrobial agent confers resistance to similar drugs \tn 
% Row Count 21 (+ 4)
\hhline{>{\arrayrulecolor{DarkBackground}}--}
\end{tabularx}
\par\addvspace{1.3em}

\begin{tabularx}{5.377cm}{x{2.4885 cm} x{2.4885 cm} }
\SetRowColor{DarkBackground}
\mymulticolumn{2}{x{5.377cm}}{\bf\textcolor{white}{microbial death rates}}  \tn
% Row 0
\SetRowColor{LightBackground}
microbial death & permanent loss of reproduction ability when in perfect environment \tn 
% Row Count 4 (+ 4)
% Row 1
\SetRowColor{white}
how to know if antimicrobial agent works & calculate microbial death rate(microbes die at constant rate) \tn 
% Row Count 8 (+ 4)
\hhline{>{\arrayrulecolor{DarkBackground}}--}
\end{tabularx}
\par\addvspace{1.3em}

\begin{tabularx}{5.377cm}{x{2.38896 cm} x{2.58804 cm} }
\SetRowColor{DarkBackground}
\mymulticolumn{2}{x{5.377cm}}{\bf\textcolor{white}{action of antimicrobial agents}}  \tn
% Row 0
\SetRowColor{LightBackground}
alteration of cell wall and membranes & in enveloped membranes when membrane is destroyed no way for viral attachments but non enveloped are have more tolerance to this method because of lack of cell wall. \tn 
% Row Count 9 (+ 9)
% Row 1
\SetRowColor{white}
damage to proteins and nucleic acid & extreme heat and chemicals are used to denature the DNA and proteins making the microbe inactive \tn 
% Row Count 14 (+ 5)
\hhline{>{\arrayrulecolor{DarkBackground}}--}
\end{tabularx}
\par\addvspace{1.3em}

\begin{tabularx}{5.377cm}{x{1.54287 cm} x{3.43413 cm} }
\SetRowColor{DarkBackground}
\mymulticolumn{2}{x{5.377cm}}{\bf\textcolor{white}{chemical microbe control}}  \tn
% Row 0
\SetRowColor{LightBackground}
chemical agents & destroy enveloped viruses, bacteria, fungi, protozoa, by affecting their cell walls and membranes, DNA and proteins \tn 
% Row Count 5 (+ 5)
% Row 1
\SetRowColor{white}
phenol & rarely used because irritates skin and smelly \tn 
% Row Count 7 (+ 2)
% Row 2
\SetRowColor{LightBackground}
phenolics & by product of phenol (less irritation) it is a low level disinfectant \tn 
% Row Count 10 (+ 3)
% Row 3
\SetRowColor{white}
alcohols & intermediate level microbe control that is ineffective against spores. \tn 
% Row Count 13 (+ 3)
% Row 4
\SetRowColor{LightBackground}
halogens & intermediate level effective agains bacteria/fungal cells and spores, some bacterial endospores, protozoan cysts and some viruses \tn 
% Row Count 18 (+ 5)
% Row 5
\SetRowColor{white}
oxidizing agents & high level release oxygen radicals (toxic oxygen). used to kill anaerobes in deep puncture wounds \tn 
% Row Count 22 (+ 4)
% Row 6
\SetRowColor{LightBackground}
surfactants (soap) & "surface active" chemicals \tn 
% Row Count 24 (+ 2)
% Row 7
\SetRowColor{white}
aldehydes & broad spectrum disinfectant (kills many microbe types) inactivate nucleic acids and enzymes \tn 
% Row Count 28 (+ 4)
% Row 8
\SetRowColor{LightBackground}
gaseous agents & cold sterilization for objects that are heat sensitive, penetrate objects readily destroying proteins and DNA \tn 
% Row Count 33 (+ 5)
\end{tabularx}
\par\addvspace{1.3em}

\vfill
\columnbreak
\begin{tabularx}{5.377cm}{x{1.54287 cm} x{3.43413 cm} }
\SetRowColor{DarkBackground}
\mymulticolumn{2}{x{5.377cm}}{\bf\textcolor{white}{chemical microbe control (cont)}}  \tn
% Row 9
\SetRowColor{LightBackground}
natural chemicals & microbial control produced by organisms \tn 
% Row Count 2 (+ 2)
\hhline{>{\arrayrulecolor{DarkBackground}}--}
\end{tabularx}
\par\addvspace{1.3em}

\begin{tabularx}{5.377cm}{p{0.4977 cm} p{0.4977 cm} }
\SetRowColor{DarkBackground}
\mymulticolumn{2}{x{5.377cm}}{\bf\textcolor{white}{retarding resistance}}  \tn
% Row 0
\SetRowColor{LightBackground}
\mymulticolumn{2}{x{5.377cm}}{administer high concentrations of drug} \tn 
% Row Count 1 (+ 1)
% Row 1
\SetRowColor{white}
\mymulticolumn{2}{x{5.377cm}}{use antimicrobials in combination} \tn 
% Row Count 2 (+ 1)
% Row 2
\SetRowColor{LightBackground}
\mymulticolumn{2}{x{5.377cm}}{limit use of antimicrobials to necessary cases} \tn 
% Row Count 3 (+ 1)
% Row 3
\SetRowColor{white}
\mymulticolumn{2}{x{5.377cm}}{development of new variations of existing drugs (e.g. second generation, third generation)} \tn 
% Row Count 5 (+ 2)
\hhline{>{\arrayrulecolor{DarkBackground}}--}
\end{tabularx}
\par\addvspace{1.3em}

\begin{tabularx}{5.377cm}{X}
\SetRowColor{DarkBackground}
\mymulticolumn{1}{x{5.377cm}}{\bf\textcolor{white}{influences of antimicrobial treatment}}  \tn
% Row 0
\SetRowColor{LightBackground}
\mymulticolumn{1}{x{5.377cm}}{1 number of microbes} \tn 
% Row Count 1 (+ 1)
% Row 1
\SetRowColor{white}
\mymulticolumn{1}{x{5.377cm}}{2 environment} \tn 
% Row Count 2 (+ 1)
% Row 2
\SetRowColor{LightBackground}
\mymulticolumn{1}{x{5.377cm}}{3 time of exposure} \tn 
% Row Count 3 (+ 1)
% Row 3
\SetRowColor{white}
\mymulticolumn{1}{x{5.377cm}}{4 microbial characteristics} \tn 
% Row Count 4 (+ 1)
\hhline{>{\arrayrulecolor{DarkBackground}}-}
\end{tabularx}
\par\addvspace{1.3em}

\begin{tabularx}{5.377cm}{X}
\SetRowColor{DarkBackground}
\mymulticolumn{1}{x{5.377cm}}{\bf\textcolor{white}{ideal microbe control}}  \tn
% Row 0
\SetRowColor{LightBackground}
\mymulticolumn{1}{x{5.377cm}}{inexpensive fast acting and stable agents} \tn 
% Row Count 1 (+ 1)
% Row 1
\SetRowColor{white}
\mymulticolumn{1}{x{5.377cm}}{controls growth of microbes} \tn 
% Row Count 2 (+ 1)
% Row 2
\SetRowColor{LightBackground}
\mymulticolumn{1}{x{5.377cm}}{harmless to humans animals and objects} \tn 
% Row Count 3 (+ 1)
\hhline{>{\arrayrulecolor{DarkBackground}}-}
\end{tabularx}
\par\addvspace{1.3em}

\begin{tabularx}{5.377cm}{X}
\SetRowColor{DarkBackground}
\mymulticolumn{1}{x{5.377cm}}{\bf\textcolor{white}{3 things to consider}}  \tn
% Row 0
\SetRowColor{LightBackground}
\mymulticolumn{1}{x{5.377cm}}{site to be treated} \tn 
% Row Count 1 (+ 1)
% Row 1
\SetRowColor{white}
\mymulticolumn{1}{x{5.377cm}}{degree of susceptibility of microbes involved} \tn 
% Row Count 2 (+ 1)
% Row 2
\SetRowColor{LightBackground}
\mymulticolumn{1}{x{5.377cm}}{environment conditions} \tn 
% Row Count 3 (+ 1)
\hhline{>{\arrayrulecolor{DarkBackground}}-}
\end{tabularx}
\par\addvspace{1.3em}

\begin{tabularx}{5.377cm}{x{1.69218 cm} x{3.28482 cm} }
\SetRowColor{DarkBackground}
\mymulticolumn{2}{x{5.377cm}}{\bf\textcolor{white}{drugs}}  \tn
% Row 0
\SetRowColor{LightBackground}
\seqsplit{chemotherapeutics} & drugs acting against a disease \tn 
% Row Count 2 (+ 2)
% Row 1
\SetRowColor{white}
\seqsplit{antimicrobials} & drugs used to treat infection \tn 
% Row Count 4 (+ 2)
% Row 2
\SetRowColor{LightBackground}
chemotherapy & the use of drugs to treat disease \tn 
% Row Count 6 (+ 2)
% Row 3
\SetRowColor{white}
antibiotics & naturally produced by an organism \tn 
% Row Count 8 (+ 2)
% Row 4
\SetRowColor{LightBackground}
\seqsplit{semisynthesis} & antibiotics chemically altered \tn 
% Row Count 10 (+ 2)
% Row 5
\SetRowColor{white}
synthesis & completely synthesized in a lab \tn 
% Row Count 12 (+ 2)
\hhline{>{\arrayrulecolor{DarkBackground}}--}
\end{tabularx}
\par\addvspace{1.3em}

\begin{tabularx}{5.377cm}{x{2.38896 cm} x{2.58804 cm} }
\SetRowColor{DarkBackground}
\mymulticolumn{2}{x{5.377cm}}{\bf\textcolor{white}{spectrum of antibiotic}}  \tn
% Row 0
\SetRowColor{LightBackground}
narrow spectrum of microbial activity & work against few types of pathogens \tn 
% Row Count 2 (+ 2)
% Row 1
\SetRowColor{white}
broad spectrum of microbial activity & drugs work against many different kinds of pathogens . when pathogen is not able to be identified broad spectrum drug will be used \tn 
% Row Count 9 (+ 7)
\hhline{>{\arrayrulecolor{DarkBackground}}--}
\end{tabularx}
\par\addvspace{1.3em}

\begin{tabularx}{5.377cm}{p{0.4977 cm} p{0.4977 cm} }
\SetRowColor{DarkBackground}
\mymulticolumn{2}{x{5.377cm}}{\bf\textcolor{white}{safety and side effects}}  \tn
% Row 0
\SetRowColor{LightBackground}
\mymulticolumn{2}{x{5.377cm}}{toxicity} \tn 
% Row Count 1 (+ 1)
% Row 1
\SetRowColor{white}
\mymulticolumn{2}{x{5.377cm}}{allergies} \tn 
% Row Count 2 (+ 1)
% Row 2
\SetRowColor{LightBackground}
\mymulticolumn{2}{x{5.377cm}}{disruption of normal microbiota} \tn 
% Row Count 3 (+ 1)
\hhline{>{\arrayrulecolor{DarkBackground}}--}
\end{tabularx}
\par\addvspace{1.3em}


% That's all folks
\end{multicols*}

\end{document}