\documentclass[10pt,a4paper]{article} % Packages \usepackage{fancyhdr} % For header and footer \usepackage{multicol} % Allows multicols in tables \usepackage{tabularx} % Intelligent column widths \usepackage{tabulary} % Used in header and footer \usepackage{hhline} % Border under tables \usepackage{graphicx} % For images \usepackage{xcolor} % For hex colours %\usepackage[utf8x]{inputenc} % For unicode character support \usepackage[T1]{fontenc} % Without this we get weird character replacements \usepackage{colortbl} % For coloured tables \usepackage{setspace} % For line height \usepackage{lastpage} % Needed for total page number \usepackage{seqsplit} % Splits long words. %\usepackage{opensans} % Can't make this work so far. Shame. Would be lovely. \usepackage[normalem]{ulem} % For underlining links % Most of the following are not required for the majority % of cheat sheets but are needed for some symbol support. \usepackage{amsmath} % Symbols \usepackage{MnSymbol} % Symbols \usepackage{wasysym} % Symbols %\usepackage[english,german,french,spanish,italian]{babel} % Languages % Document Info \author{GHMCA1216} \pdfinfo{ /Title (tumor-markers.pdf) /Creator (Cheatography) /Author (GHMCA1216) /Subject (Tumor Markers Cheat Sheet) } % Lengths and widths \addtolength{\textwidth}{6cm} \addtolength{\textheight}{-1cm} \addtolength{\hoffset}{-3cm} \addtolength{\voffset}{-2cm} \setlength{\tabcolsep}{0.2cm} % Space between columns \setlength{\headsep}{-12pt} % Reduce space between header and content \setlength{\headheight}{85pt} % If less, LaTeX automatically increases it \renewcommand{\footrulewidth}{0pt} % Remove footer line \renewcommand{\headrulewidth}{0pt} % Remove header line \renewcommand{\seqinsert}{\ifmmode\allowbreak\else\-\fi} % Hyphens in seqsplit % This two commands together give roughly % the right line height in the tables \renewcommand{\arraystretch}{1.3} \onehalfspacing % Commands \newcommand{\SetRowColor}[1]{\noalign{\gdef\RowColorName{#1}}\rowcolor{\RowColorName}} % Shortcut for row colour \newcommand{\mymulticolumn}[3]{\multicolumn{#1}{>{\columncolor{\RowColorName}}#2}{#3}} % For coloured multi-cols \newcolumntype{x}[1]{>{\raggedright}p{#1}} % New column types for ragged-right paragraph columns \newcommand{\tn}{\tabularnewline} % Required as custom column type in use % Font and Colours \definecolor{HeadBackground}{HTML}{333333} \definecolor{FootBackground}{HTML}{666666} \definecolor{TextColor}{HTML}{333333} \definecolor{DarkBackground}{HTML}{333EA3} \definecolor{LightBackground}{HTML}{F2F2F9} \renewcommand{\familydefault}{\sfdefault} \color{TextColor} % Header and Footer \pagestyle{fancy} \fancyhead{} % Set header to blank \fancyfoot{} % Set footer to blank \fancyhead[L]{ \noindent \begin{multicols}{3} \begin{tabulary}{5.8cm}{C} \SetRowColor{DarkBackground} \vspace{-7pt} {\parbox{\dimexpr\textwidth-2\fboxsep\relax}{\noindent \hspace*{-6pt}\includegraphics[width=5.8cm]{/web/www.cheatography.com/public/images/cheatography_logo.pdf}} } \end{tabulary} \columnbreak \begin{tabulary}{11cm}{L} \vspace{-2pt}\large{\bf{\textcolor{DarkBackground}{\textrm{Tumor Markers Cheat Sheet}}}} \\ \normalsize{by \textcolor{DarkBackground}{GHMCA1216} via \textcolor{DarkBackground}{\uline{cheatography.com/148916/cs/33237/}}} \end{tabulary} \end{multicols}} \fancyfoot[L]{ \footnotesize \noindent \begin{multicols}{3} \begin{tabulary}{5.8cm}{LL} \SetRowColor{FootBackground} \mymulticolumn{2}{p{5.377cm}}{\bf\textcolor{white}{Cheatographer}} \\ \vspace{-2pt}GHMCA1216 \\ \uline{cheatography.com/ghmca1216} \\ \end{tabulary} \vfill \columnbreak \begin{tabulary}{5.8cm}{L} \SetRowColor{FootBackground} \mymulticolumn{1}{p{5.377cm}}{\bf\textcolor{white}{Cheat Sheet}} \\ \vspace{-2pt}Published 19th July, 2022.\\ Updated 19th July, 2022.\\ Page {\thepage} of \pageref{LastPage}. \end{tabulary} \vfill \columnbreak \begin{tabulary}{5.8cm}{L} \SetRowColor{FootBackground} \mymulticolumn{1}{p{5.377cm}}{\bf\textcolor{white}{Sponsor}} \\ \SetRowColor{white} \vspace{-5pt} %\includegraphics[width=48px,height=48px]{dave.jpeg} Measure your website readability!\\ www.readability-score.com \end{tabulary} \end{multicols}} \begin{document} \raggedright \raggedcolumns % Set font size to small. Switch to any value % from this page to resize cheat sheet text: % www.emerson.emory.edu/services/latex/latex_169.html \footnotesize % Small font. \begin{multicols*}{3} \begin{tabularx}{5.377cm}{X} \SetRowColor{DarkBackground} \mymulticolumn{1}{x{5.377cm}}{\bf\textcolor{white}{Epithelial Tumor Markers}} \tn % Row 0 \SetRowColor{LightBackground} \mymulticolumn{1}{x{5.377cm}}{{\bf{Keratin}}} \tn % Row Count 1 (+ 1) % Row 1 \SetRowColor{white} \mymulticolumn{1}{x{5.377cm}}{Highly Sensitive Marker for epithelial Cells} \tn % Row Count 2 (+ 1) % Row 2 \SetRowColor{LightBackground} \mymulticolumn{1}{x{5.377cm}}{{\bf{Epithelial Membrane Antigen (EMA)}}} \tn % Row Count 3 (+ 1) % Row 3 \SetRowColor{white} \mymulticolumn{1}{x{5.377cm}}{High molecular weight protein that is helpful for determining the site of tumor} \tn % Row Count 5 (+ 2) % Row 4 \SetRowColor{LightBackground} \mymulticolumn{1}{x{5.377cm}}{{\bf{Carcinoembryonic Antigen (CEA)}}} \tn % Row Count 6 (+ 1) % Row 5 \SetRowColor{white} \mymulticolumn{1}{x{5.377cm}}{Oncofetal antigen in carcinomas of GIT, pancreas, lung, breast, ovary, uterus, and cervix} \tn % Row Count 8 (+ 2) % Row 6 \SetRowColor{LightBackground} \mymulticolumn{1}{x{5.377cm}}{{\bf{Thyroid Transcription Factor-1 (TFF-1)}}} \tn % Row Count 9 (+ 1) % Row 7 \SetRowColor{white} \mymulticolumn{1}{x{5.377cm}}{Useful for distinguishing lung adenocarcinomas from mesotheliomas from the mesothelium} \tn % Row Count 11 (+ 2) % Row 8 \SetRowColor{LightBackground} \mymulticolumn{1}{x{5.377cm}}{{\bf{Prostate Specific Antigen (PSA)}}} \tn % Row Count 12 (+ 1) % Row 9 \SetRowColor{white} \mymulticolumn{1}{x{5.377cm}}{Extremely useful in diagnosis of prostatic adenocarcinoma} \tn % Row Count 14 (+ 2) \hhline{>{\arrayrulecolor{DarkBackground}}-} \end{tabularx} \par\addvspace{1.3em} \begin{tabularx}{5.377cm}{x{2.4885 cm} x{2.4885 cm} } \SetRowColor{DarkBackground} \mymulticolumn{2}{x{5.377cm}}{\bf\textcolor{white}{Intermediate Filament Markers}} \tn % Row 0 \SetRowColor{LightBackground} \mymulticolumn{2}{x{5.377cm}}{{\bf{Actin}}} \tn % Row Count 1 (+ 1) % Row 1 \SetRowColor{white} \mymulticolumn{2}{x{5.377cm}}{Tumors of smooth, skeletal, and cardiac muscle} \tn % Row Count 2 (+ 1) % Row 2 \SetRowColor{LightBackground} \mymulticolumn{2}{x{5.377cm}}{{\bf{Vimentin}}} \tn % Row Count 3 (+ 1) % Row 3 \SetRowColor{white} \mymulticolumn{2}{x{5.377cm}}{Melanoma\{\{nl\}\}Schwannomas} \tn % Row Count 4 (+ 1) % Row 4 \SetRowColor{LightBackground} \mymulticolumn{2}{x{5.377cm}}{{\bf{Desmin}}} \tn % Row Count 5 (+ 1) % Row 5 \SetRowColor{white} \mymulticolumn{2}{x{5.377cm}}{Leiomymoa\{\{nl\}\}Rhabdomyosarcoma} \tn % Row Count 6 (+ 1) % Row 6 \SetRowColor{LightBackground} \mymulticolumn{2}{x{5.377cm}}{{\bf{Glial Fibrillary Acidic Protein (GFAP)}}} \tn % Row Count 7 (+ 1) % Row 7 \SetRowColor{white} Astrocytoma\{\{nl\}\}Ependomyomas\{\{nl\}\}Oligodendrogliomas\{\{nl\}\}Medulloblastoma & {\bf{If negative: Non-CNS Tumors}}\{\{nl\}\}Meningiomas\{\{nl\}\}Metastatic Carcinomas\{\{nl\}\}Lymphomas \tn % Row Count 12 (+ 5) % Row 8 \SetRowColor{LightBackground} \mymulticolumn{2}{x{5.377cm}}{Neurofilaments} \tn % Row Count 13 (+ 1) % Row 9 \SetRowColor{white} \mymulticolumn{2}{x{5.377cm}}{{\bf{Neurofilaments (NF)}}} \tn % Row Count 14 (+ 1) % Row 10 \SetRowColor{LightBackground} Neuroblastoma\{\{nl\}\}Ganglioneuromas\{\{nl\}\}Chemodectomas\{\{nl\}\}Pheochromocytomas & {\bf{Note:}} Show neuroendocrine differentiation \tn % Row Count 18 (+ 4) % Row 11 \SetRowColor{white} \mymulticolumn{2}{x{5.377cm}}{{\bf{S100 Protein}}} \tn % Row Count 19 (+ 1) \hhline{>{\arrayrulecolor{DarkBackground}}--} \end{tabularx} \par\addvspace{1.3em} \begin{tabularx}{5.377cm}{x{2.28942 cm} x{2.68758 cm} } \SetRowColor{DarkBackground} \mymulticolumn{2}{x{5.377cm}}{\bf\textcolor{white}{Mesenchymal Tumor Markers}} \tn % Row 0 \SetRowColor{LightBackground} \mymulticolumn{2}{x{5.377cm}}{{\bf{Myogenic Tumors}}} \tn % Row Count 1 (+ 1) % Row 1 \SetRowColor{white} \mymulticolumn{2}{x{5.377cm}}{Tumors of skeletal muscle origin (Positive for muscle-specific actin and desmin)} \tn % Row Count 3 (+ 2) % Row 2 \SetRowColor{LightBackground} {\bf{Fibrohistocytic Tumor}} & (CD68 and FAM 56) \tn % Row Count 5 (+ 2) % Row 3 \SetRowColor{white} Malignant fibrohistocytic sarcomas & {\bf{Note:}} Combined with alpha1-Antitrypsin and \seqsplit{alpha1-antichymotrypsin} \tn % Row Count 9 (+ 4) % Row 4 \SetRowColor{LightBackground} {\bf{Vascular Tumor}} & Factor VII-related Antigen, CD31, Ulex Eurpaeus 1 (UEA) \tn % Row Count 12 (+ 3) \hhline{>{\arrayrulecolor{DarkBackground}}--} \end{tabularx} \par\addvspace{1.3em} \begin{tabularx}{5.377cm}{p{0.4977 cm} p{0.4977 cm} } \SetRowColor{DarkBackground} \mymulticolumn{2}{x{5.377cm}}{\bf\textcolor{white}{Cancer-Associated Genes}} \tn % Row 0 \SetRowColor{LightBackground} \mymulticolumn{2}{x{5.377cm}}{{\bf{p53}}} \tn % Row Count 1 (+ 1) % Row 1 \SetRowColor{white} \mymulticolumn{2}{x{5.377cm}}{Tumor suppressor gene} \tn % Row Count 2 (+ 1) % Row 2 \SetRowColor{LightBackground} \mymulticolumn{2}{x{5.377cm}}{{\bf{C-erb-2/c-myc/ras}}} \tn % Row Count 3 (+ 1) % Row 3 \SetRowColor{white} \mymulticolumn{2}{x{5.377cm}}{Cellular oncogene found to be activated in breast cancer} \tn % Row Count 5 (+ 2) \hhline{>{\arrayrulecolor{DarkBackground}}--} \end{tabularx} \par\addvspace{1.3em} \begin{tabularx}{5.377cm}{X} \SetRowColor{DarkBackground} \mymulticolumn{1}{x{5.377cm}}{\bf\textcolor{white}{Epithelial Membrane Antigen (EMA)}} \tn % Row 0 \SetRowColor{LightBackground} \mymulticolumn{1}{x{5.377cm}}{{\bf{EMA+}}} \tn % Row Count 1 (+ 1) % Row 1 \SetRowColor{white} \mymulticolumn{1}{x{5.377cm}}{Adenocarcinoma of Breast\{\{nl\}\}Adenocarcinoma of Lungs\{\{nl\}\}Adenocarcinoma of Kidneys} \tn % Row Count 3 (+ 2) % Row 2 \SetRowColor{LightBackground} \mymulticolumn{1}{x{5.377cm}}{{\bf{EMA-}}} \tn % Row Count 4 (+ 1) % Row 3 \SetRowColor{white} \mymulticolumn{1}{x{5.377cm}}{Non-epithelial tumors\{\{nl\}\}Sarcomas Lymphomas\{\{nl\}\}Melanomas} \tn % Row Count 6 (+ 2) % Row 4 \SetRowColor{LightBackground} \mymulticolumn{1}{x{5.377cm}}{{\bf{EMA Non-reactive}}} \tn % Row Count 7 (+ 1) % Row 5 \SetRowColor{white} \mymulticolumn{1}{x{5.377cm}}{Hepatocellular Carcinoma\{\{nl\}\}Adrenal Carcinoma\{\{nl\}\}Embryonal Carcinoma} \tn % Row Count 9 (+ 2) \hhline{>{\arrayrulecolor{DarkBackground}}-} \end{tabularx} \par\addvspace{1.3em} \begin{tabularx}{5.377cm}{X} \SetRowColor{DarkBackground} \mymulticolumn{1}{x{5.377cm}}{\bf\textcolor{white}{Carcinoembryonic Antigen (CEA)}} \tn % Row 0 \SetRowColor{LightBackground} \mymulticolumn{1}{x{5.377cm}}{{\bf{CEA+}}} \tn % Row Count 1 (+ 1) % Row 1 \SetRowColor{white} \mymulticolumn{1}{x{5.377cm}}{Adenocarcinoma} \tn % Row Count 2 (+ 1) % Row 2 \SetRowColor{LightBackground} \mymulticolumn{1}{x{5.377cm}}{{\bf{CEA-}}} \tn % Row Count 3 (+ 1) % Row 3 \SetRowColor{white} \mymulticolumn{1}{x{5.377cm}}{Mesothelioma} \tn % Row Count 4 (+ 1) % Row 4 \SetRowColor{LightBackground} \mymulticolumn{1}{x{5.377cm}}{{\bf{CEA Non-reactive}}} \tn % Row Count 5 (+ 1) % Row 5 \SetRowColor{white} \mymulticolumn{1}{x{5.377cm}}{Prostate Carcinoma\{\{nl\}\}Thyroid Carinoma\{\{nl\}\}Renal Carcinoma} \tn % Row Count 7 (+ 2) \hhline{>{\arrayrulecolor{DarkBackground}}-} \end{tabularx} \par\addvspace{1.3em} \begin{tabularx}{5.377cm}{X} \SetRowColor{DarkBackground} \mymulticolumn{1}{x{5.377cm}}{\bf\textcolor{white}{Prostate Specific Antigen (PSA)}} \tn % Row 0 \SetRowColor{LightBackground} \mymulticolumn{1}{x{5.377cm}}{{\bf{PSA+}}} \tn % Row Count 1 (+ 1) % Row 1 \SetRowColor{white} \mymulticolumn{1}{x{5.377cm}}{Prostatic Adenocarcinoma\{\{nl\}\}Pancreatic Tumor\{\{nl\}\}Salivary Gland Tumor} \tn % Row Count 3 (+ 2) \hhline{>{\arrayrulecolor{DarkBackground}}-} \end{tabularx} \par\addvspace{1.3em} \begin{tabularx}{5.377cm}{p{0.4977 cm} p{0.4977 cm} } \SetRowColor{DarkBackground} \mymulticolumn{2}{x{5.377cm}}{\bf\textcolor{white}{Germ Cell Tumor Markers}} \tn % Row 0 \SetRowColor{LightBackground} \mymulticolumn{2}{x{5.377cm}}{{\bf{Human Chorionic Gonadotropin (HCG)}}} \tn % Row Count 1 (+ 1) % Row 1 \SetRowColor{white} \mymulticolumn{2}{x{5.377cm}}{Marker for Chorio-carcinoma} \tn % Row Count 2 (+ 1) % Row 2 \SetRowColor{LightBackground} \mymulticolumn{2}{x{5.377cm}}{{\bf{Alpha-fetoprotein (AFP)}}} \tn % Row Count 3 (+ 1) % Row 3 \SetRowColor{white} \mymulticolumn{2}{x{5.377cm}}{Embryonal Carcinomas\{\{nl\}\}Treatomas\{\{nl\}\}Hepatocelullar Carcinomas} \tn % Row Count 5 (+ 2) % Row 4 \SetRowColor{LightBackground} \mymulticolumn{2}{x{5.377cm}}{{\bf{Placenta-like Alkaline Phosphatase (PLAP)}}} \tn % Row Count 6 (+ 1) % Row 5 \SetRowColor{white} \mymulticolumn{2}{x{5.377cm}}{Most embryonal CA\{\{nl\}\}Choriocarcinoma\{\{nl\}\}Endodermal Sinus Tumors\{\{nl\}\}Majority of seminomas} \tn % Row Count 8 (+ 2) \hhline{>{\arrayrulecolor{DarkBackground}}--} \end{tabularx} \par\addvspace{1.3em} \begin{tabularx}{5.377cm}{p{0.4977 cm} p{0.4977 cm} } \SetRowColor{DarkBackground} \mymulticolumn{2}{x{5.377cm}}{\bf\textcolor{white}{Lymphomas}} \tn % Row 0 \SetRowColor{LightBackground} \mymulticolumn{2}{x{5.377cm}}{{\bf{Leukocyte Common Antigen (LCA)}}} \tn % Row Count 1 (+ 1) % Row 1 \SetRowColor{white} \mymulticolumn{2}{x{5.377cm}}{CD45} \tn % Row Count 2 (+ 1) % Row 2 \SetRowColor{LightBackground} \mymulticolumn{2}{x{5.377cm}}{{\bf{T-cells}}} \tn % Row Count 3 (+ 1) % Row 3 \SetRowColor{white} \mymulticolumn{2}{x{5.377cm}}{CD3, CD4, CD8} \tn % Row Count 4 (+ 1) % Row 4 \SetRowColor{LightBackground} \mymulticolumn{2}{x{5.377cm}}{{\bf{B-cells}}} \tn % Row Count 5 (+ 1) % Row 5 \SetRowColor{white} \mymulticolumn{2}{x{5.377cm}}{CD19, CD20, CD23} \tn % Row Count 6 (+ 1) % Row 6 \SetRowColor{LightBackground} \mymulticolumn{2}{x{5.377cm}}{{\bf{Reed-Sternberg Cells}}} \tn % Row Count 7 (+ 1) % Row 7 \SetRowColor{white} \mymulticolumn{2}{x{5.377cm}}{CD15, CD30} \tn % Row Count 8 (+ 1) % Row 8 \SetRowColor{LightBackground} \mymulticolumn{2}{x{5.377cm}}{{\bf{Immunoglobulin Light and Heavy Chains}}} \tn % Row Count 9 (+ 1) \hhline{>{\arrayrulecolor{DarkBackground}}--} \end{tabularx} \par\addvspace{1.3em} \begin{tabularx}{5.377cm}{X} \SetRowColor{DarkBackground} \mymulticolumn{1}{x{5.377cm}}{\bf\textcolor{white}{CK7+, CK20-}} \tn % Row 0 \SetRowColor{LightBackground} \mymulticolumn{1}{x{5.377cm}}{{\bf{CK7+, CK20-}}} \tn % Row Count 1 (+ 1) % Row 1 \SetRowColor{white} \mymulticolumn{1}{x{5.377cm}}{Lung Carcinoma\{\{nl\}\}Breast Carcinoma\{\{nl\}\}Uterus Carcinoma\{\{nl\}\}Ovaries Carcinoma\{\{nl\}\}Serous Tumors} \tn % Row Count 3 (+ 2) % Row 2 \SetRowColor{LightBackground} \mymulticolumn{1}{x{5.377cm}}{{\bf{CK7-, CK20+}}} \tn % Row Count 4 (+ 1) % Row 3 \SetRowColor{white} \mymulticolumn{1}{x{5.377cm}}{Colon Carcinoma\{\{nl\}\}Stomach Carcinoma} \tn % Row Count 5 (+ 1) % Row 4 \SetRowColor{LightBackground} \mymulticolumn{1}{x{5.377cm}}{{\bf{CK7+, CK20+}}} \tn % Row Count 6 (+ 1) % Row 5 \SetRowColor{white} \mymulticolumn{1}{x{5.377cm}}{Transitional Cell Carcinoma (Bladder)\{\{nl\}\}Mucinous Ovarian Tumor} \tn % Row Count 8 (+ 2) % Row 6 \SetRowColor{LightBackground} \mymulticolumn{1}{x{5.377cm}}{{\bf{CK7-, CK20-}}} \tn % Row Count 9 (+ 1) % Row 7 \SetRowColor{white} \mymulticolumn{1}{x{5.377cm}}{Renal Cell Carcinoma\{\{nl\}\}Hepatocellular Carcinoma\{\{nl\}\}Prostatic Adenocarcinoma\{\{nl\}\}Thyroid Carcinoma\{\{nl\}\}Squamous Cell Carcinoma} \tn % Row Count 12 (+ 3) \hhline{>{\arrayrulecolor{DarkBackground}}-} \end{tabularx} \par\addvspace{1.3em} \begin{tabularx}{5.377cm}{X} \SetRowColor{DarkBackground} \mymulticolumn{1}{x{5.377cm}}{\bf\textcolor{white}{Thyroid Transcription Factor-1 (TFF-1)}} \tn % Row 0 \SetRowColor{LightBackground} \mymulticolumn{1}{x{5.377cm}}{{\bf{TFF-1+}}} \tn % Row Count 1 (+ 1) % Row 1 \SetRowColor{white} \mymulticolumn{1}{x{5.377cm}}{Thyroid, Lung, Neuroendocrine Tumors\{\{nl\}\}Medullary Carcinoma\{\{nl\}\}Carcinoid Tumor\{\{nl\}\}Small Cell Tumor of Lungs} \tn % Row Count 4 (+ 3) \hhline{>{\arrayrulecolor{DarkBackground}}-} \end{tabularx} \par\addvspace{1.3em} \begin{tabularx}{5.377cm}{x{1.73926 cm} x{1.64772 cm} x{1.19002 cm} } \SetRowColor{DarkBackground} \mymulticolumn{3}{x{5.377cm}}{\bf\textcolor{white}{Neuroendocrine Markers}} \tn % Row 0 \SetRowColor{LightBackground} \mymulticolumn{3}{x{5.377cm}}{{\bf{Neuron-Specific Enolase}}} \tn % Row Count 1 (+ 1) % Row 1 \SetRowColor{white} \mymulticolumn{3}{x{5.377cm}}{Provides strong evidence of neural or neuroendocrine differentiation} \tn % Row Count 3 (+ 2) % Row 2 \SetRowColor{LightBackground} \mymulticolumn{3}{x{5.377cm}}{{\bf{Chromogranin}}} \tn % Row Count 4 (+ 1) % Row 3 \SetRowColor{white} Neuroendocrine differentiation\{\{nl\}\}Granular \seqsplit{immunoreactivity} & {\bf{K+,C-}}\{\{nl\}\}Neuroendocrine Carcinoma & {\bf{K-,C+}}\{\{nl\}\}Paraganglioma \tn % Row Count 9 (+ 5) % Row 4 \SetRowColor{LightBackground} \mymulticolumn{3}{x{5.377cm}}{{\bf{Synaptophysin}}} \tn % Row Count 10 (+ 1) % Row 5 \SetRowColor{white} \mymulticolumn{3}{x{5.377cm}}{Associated with presynaptic vesicles of neurons} \tn % Row Count 11 (+ 1) \hhline{>{\arrayrulecolor{DarkBackground}}---} \end{tabularx} \par\addvspace{1.3em} \begin{tabularx}{5.377cm}{x{2.88666 cm} x{2.09034 cm} } \SetRowColor{DarkBackground} \mymulticolumn{2}{x{5.377cm}}{\bf\textcolor{white}{Melanomas}} \tn % Row 0 \SetRowColor{LightBackground} \mymulticolumn{2}{x{5.377cm}}{{\bf{Melanosome (HMB-45)}}} \tn % Row Count 1 (+ 1) % Row 1 \SetRowColor{white} Detection of primary and secondary melanomas & Highly sensitive and specific \tn % Row Count 3 (+ 2) % Row 2 \SetRowColor{LightBackground} \mymulticolumn{2}{x{5.377cm}}{{\bf{Melan-A (MART-1)}}} \tn % Row Count 4 (+ 1) % Row 3 \SetRowColor{white} \mymulticolumn{2}{x{5.377cm}}{Encodes melanoma-specific antigen in normal pigmented cells of skin, retina, and certain adrenocortical tumors} \tn % Row Count 7 (+ 3) \hhline{>{\arrayrulecolor{DarkBackground}}--} \end{tabularx} \par\addvspace{1.3em} \begin{tabularx}{5.377cm}{p{0.4977 cm} p{0.4977 cm} } \SetRowColor{DarkBackground} \mymulticolumn{2}{x{5.377cm}}{\bf\textcolor{white}{Cell Proliferation Markers}} \tn % Row 0 \SetRowColor{LightBackground} \mymulticolumn{2}{x{5.377cm}}{{\bf{Ki-67 (MIB-1) and Proliferating Cell Nuclear Antigen (PCNA)}}} \tn % Row Count 2 (+ 2) % Row 1 \SetRowColor{white} \mymulticolumn{2}{x{5.377cm}}{Assess the proliferation of tumor cells} \tn % Row Count 3 (+ 1) \hhline{>{\arrayrulecolor{DarkBackground}}--} \end{tabularx} \par\addvspace{1.3em} % That's all folks \end{multicols*} \end{document}