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% Most of the following are not required for the majority
% of cheat sheets but are needed for some symbol support.
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% Document Info
\author{{[}deleted{]}}
\pdfinfo{
  /Title (reoviridae.pdf)
  /Creator (Cheatography)
  /Author ({[}deleted{]})
  /Subject (Reoviridae Cheat Sheet)
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% Header and Footer
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\noindent
\begin{multicols}{3}
\begin{tabulary}{5.8cm}{C}
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    \vspace{-7pt}
    {\parbox{\dimexpr\textwidth-2\fboxsep\relax}{\noindent
        \hspace*{-6pt}\includegraphics[width=5.8cm]{/web/www.cheatography.com/public/images/cheatography_logo.pdf}}
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\begin{tabulary}{11cm}{L}
    \vspace{-2pt}\large{\bf{\textcolor{DarkBackground}{\textrm{Reoviridae Cheat Sheet}}}} \\
    \normalsize{by \textcolor{DarkBackground}{{[}deleted{]}} via \textcolor{DarkBackground}{\uline{cheatography.com/140849/cs/30028/}}}
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\noindent
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  \mymulticolumn{2}{p{5.377cm}}{\bf\textcolor{white}{Cheatographer}}  \\
  \vspace{-2pt}{[}deleted{]} \\
  \uline{cheatography.com/deleted-140849} \\
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  \mymulticolumn{1}{p{5.377cm}}{\bf\textcolor{white}{Cheat Sheet}}  \\
   \vspace{-2pt}Published 3rd December, 2021.\\
   Updated 2nd December, 2021.\\
   Page {\thepage} of \pageref{LastPage}.
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  %\includegraphics[width=48px,height=48px]{dave.jpeg}
  Measure your website readability!\\
  www.readability-score.com
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\begin{document}
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% Set font size to small. Switch to any value
% from this page to resize cheat sheet text:
% www.emerson.emory.edu/services/latex/latex_169.html
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\begin{multicols*}{3}

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\mymulticolumn{2}{x{5.377cm}}{\bf\textcolor{white}{Basic Information}}  \tn
% Row 0
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\mymulticolumn{2}{x{5.377cm}}{	Linear double-stranded RNA genome and non-enveloped} \tn 
% Row Count 2 (+ 2)
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\mymulticolumn{2}{x{5.377cm}}{\bf\textcolor{white}{Sub-families}}  \tn
% Row 0
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\mymulticolumn{2}{x{5.377cm}}{sedoreovirinae} \tn 
% Row Count 1 (+ 1)
% Row 1
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\mymulticolumn{2}{x{5.377cm}}{spinareovirinae} \tn 
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% Row 0
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% Row 1
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\mymulticolumn{2}{x{5.377cm}}{dsRNA} \tn 
% Row Count 2 (+ 1)
% Row 2
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\mymulticolumn{2}{x{5.377cm}}{11 segments} \tn 
% Row Count 3 (+ 1)
% Row 3
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\mymulticolumn{2}{x{5.377cm}}{size of genome - 10 - 27 kb} \tn 
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\mymulticolumn{3}{x{5.377cm}}{\bf\textcolor{white}{Protein}}  \tn
% Row 0
\SetRowColor{LightBackground}
6 structural proteins & VP1 & RdRp \tn 
% Row Count 2 (+ 2)
% Row 1
\SetRowColor{white}
 & VP2 & Core protein \tn 
% Row Count 3 (+ 1)
% Row 2
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 & VP3 & Guanylyltransferase \tn 
% Row Count 4 (+ 1)
% Row 3
\SetRowColor{white}
 & VP4 & spike protein - cleaves VP5 and VP8 \tn 
% Row Count 6 (+ 2)
% Row 4
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 & VP6 & Intermediate capsid \tn 
% Row Count 7 (+ 1)
% Row 5
\SetRowColor{white}
 & VP7 & neutralization of Ag \tn 
% Row Count 8 (+ 1)
% Row 6
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6 Non-structural protein & NSP1 & Interferon antagonist \tn 
% Row Count 10 (+ 2)
% Row 7
\SetRowColor{white}
 & NSP2 & NTPase - viroplasms with NSP5 \tn 
% Row Count 12 (+ 2)
% Row 8
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 & NSP3 & Translation enhancer \tn 
% Row Count 13 (+ 1)
% Row 9
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 & NSP4 & Viroporins \tn 
% Row Count 14 (+ 1)
% Row 10
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 & NSP5 & Viroplasms with NSP2 \tn 
% Row Count 15 (+ 1)
% Row 11
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 & NSP6 & Interacts with NSP5 \tn 
% Row Count 16 (+ 1)
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\mymulticolumn{1}{x{5.377cm}}{\bf\textcolor{white}{Diagram}}  \tn
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\mymulticolumn{1}{p{5.377cm}}{\vspace{1px}\centerline{\includegraphics[width=5.1cm]{/web/www.cheatography.com/public/uploads/varun-kailaje_1638469049_istockphoto-940226446-612x612.jpg}}} \tn 
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\mymulticolumn{2}{x{5.377cm}}{\bf\textcolor{white}{Replication}}  \tn
% Row 0
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\mymulticolumn{2}{x{5.377cm}}{	Efficient replication requires cleavage of the outer capsid spike protein VP4, which allows the structurally flexible spike protein, VP4, to undergo conformational changes to interact with a series of cellular receptors.} \tn 
% Row Count 5 (+ 5)
% Row 1
\SetRowColor{white}
\mymulticolumn{2}{x{5.377cm}}{	The virus is internalized by receptor-mediated endocytosis. The low calcium of the endosome releases outer capsid VP7 trimers, resulting in a conformational change in the VP4 spike protein that releases the transcriptionally active double-layered particles into the cytoplasm.} \tn 
% Row Count 11 (+ 6)
% Row 2
\SetRowColor{LightBackground}
\mymulticolumn{2}{x{5.377cm}}{	Viral messenger RNAs (mRNAs) are used to translate proteins and as templates for RNA genome replication and packaging into newly made double-layered particles (DLPs) that occurs in specialized structures called viroplasms that co-localize and require components of lipid droplets for formation.} \tn 
% Row Count 17 (+ 6)
% Row 3
\SetRowColor{white}
\mymulticolumn{2}{x{5.377cm}}{	Triple-layered particle (TLP) assembly is completed by a unique process involving binding of newly made DLPs to NSP4 that serves as an intracellular receptor, followed by particles budding into the endoplasmic reticulum} \tn 
% Row Count 22 (+ 5)
% Row 4
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\mymulticolumn{2}{x{5.377cm}}{During this process, transient enveloped particles are seen, the outer capsid proteins VP4 and VP7 are assembled, and the transient envelope is lost.} \tn 
% Row Count 25 (+ 3)
% Row 5
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\mymulticolumn{2}{x{5.377cm}}{	The viral glycoproteins do not traffic to the Golgi. In polarized epithelial cells, particles are released both by viral lysis and by a nonclassical vesicular transport mechanism.} \tn 
% Row Count 29 (+ 4)
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% That's all folks
\end{multicols*}

\end{document}