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% Document Info
\author{Dani (Dan\_Niel)}
\pdfinfo{
  /Title (alterations-in-oxygenation-transport.pdf)
  /Creator (Cheatography)
  /Author (Dani (Dan\_Niel))
  /Subject (Alterations in Oxygenation (Transport) Cheat Sheet)
}

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\noindent
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    {\parbox{\dimexpr\textwidth-2\fboxsep\relax}{\noindent
        \hspace*{-6pt}\includegraphics[width=5.8cm]{/web/www.cheatography.com/public/images/cheatography_logo.pdf}}
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\begin{tabulary}{11cm}{L}
    \vspace{-2pt}\large{\bf{\textcolor{DarkBackground}{\textrm{Alterations in Oxygenation (Transport) Cheat Sheet}}}} \\
    \normalsize{by \textcolor{DarkBackground}{Dani (Dan\_Niel)} via \textcolor{DarkBackground}{\uline{cheatography.com/131883/cs/26649/}}}
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\noindent
\begin{multicols}{3}
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  \mymulticolumn{2}{p{5.377cm}}{\bf\textcolor{white}{Cheatographer}}  \\
  \vspace{-2pt}Dani (Dan\_Niel) \\
  \uline{cheatography.com/dan-niel} \\
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  \mymulticolumn{1}{p{5.377cm}}{\bf\textcolor{white}{Cheat Sheet}}  \\
   \vspace{-2pt}Published 19th February, 2021.\\
   Updated 19th February, 2021.\\
   Page {\thepage} of \pageref{LastPage}.
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  %\includegraphics[width=48px,height=48px]{dave.jpeg}
  Measure your website readability!\\
  www.readability-score.com
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\begin{document}
\raggedright
\raggedcolumns

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% www.emerson.emory.edu/services/latex/latex_169.html
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\begin{multicols*}{3}

\begin{tabularx}{5.377cm}{p{0.4977 cm} p{0.4977 cm} }
\SetRowColor{DarkBackground}
\mymulticolumn{2}{x{5.377cm}}{\bf\textcolor{white}{Thalassemia}}  \tn
% Row 0
\SetRowColor{LightBackground}
\mymulticolumn{2}{x{5.377cm}}{{\bf{Autosomal recessive}} genetic disorder of inadequate production of normal hemoglobin. found in meditteranean ethnic groups.} \tn 
% Row Count 3 (+ 3)
% Row 1
\SetRowColor{white}
\mymulticolumn{2}{x{5.377cm}}{{\bf{Clinical Manifestation}}} \tn 
% Row Count 4 (+ 1)
% Row 2
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\mymulticolumn{2}{x{5.377cm}}{Asymptomatic | Major retardation | Life threatening} \tn 
% Row Count 6 (+ 2)
% Row 3
\SetRowColor{white}
\mymulticolumn{2}{x{5.377cm}}{Splenomegaly, Heptomegaly} \tn 
% Row Count 7 (+ 1)
% Row 4
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\mymulticolumn{2}{x{5.377cm}}{{\bf{Pathophysiology}}} \tn 
% Row Count 8 (+ 1)
% Row 5
\SetRowColor{white}
\mymulticolumn{2}{x{5.377cm}}{Genetic defect, synthesis of one of a or b globin chains, production of abnormal Hgb and RBC, Hemolysis, Anemia} \tn 
% Row Count 11 (+ 3)
% Row 6
\SetRowColor{LightBackground}
\mymulticolumn{2}{x{5.377cm}}{{\bf{Collaborative Care}}} \tn 
% Row Count 12 (+ 1)
% Row 7
\SetRowColor{white}
\mymulticolumn{2}{x{5.377cm}}{• No specific drug or diet are effective for treatment} \tn 
% Row Count 14 (+ 2)
% Row 8
\SetRowColor{LightBackground}
\mymulticolumn{2}{x{5.377cm}}{• Minor (hetero-beta) : body adapts to low Hgb} \tn 
% Row Count 15 (+ 1)
% Row 9
\SetRowColor{white}
\mymulticolumn{2}{x{5.377cm}}{• Major (Homo-beta) : Blood transfusions with IV deferoxamine (used to remove excess iron from the body)} \tn 
% Row Count 18 (+ 3)
\hhline{>{\arrayrulecolor{DarkBackground}}--}
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\mymulticolumn{2}{x{5.377cm}}{\bf\textcolor{white}{Polycythemia}}  \tn
% Row 0
\SetRowColor{LightBackground}
\mymulticolumn{2}{x{5.377cm}}{A net increase in the total number of Red blood cells. {\bf{Overproduction may be due to:}}} \tn 
% Row Count 2 (+ 2)
% Row 1
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\mymulticolumn{2}{x{5.377cm}}{- myeloproliferative syndrome in bone marrow} \tn 
% Row Count 3 (+ 1)
% Row 2
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\mymulticolumn{2}{x{5.377cm}}{- reaction to chronically low oxy lvls or malignancy} \tn 
% Row Count 5 (+ 2)
% Row 3
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\mymulticolumn{2}{x{5.377cm}}{{\bf{Pathophysiology}}} \tn 
% Row Count 6 (+ 1)
% Row 4
\SetRowColor{LightBackground}
\mymulticolumn{2}{x{5.377cm}}{Myeloproliferative due to hypoxia, the stem cell grow uncontrollably, BM becomes Hypercellular, Blood becomes thick to sluggish circulation, BM becomes fibrotic.} \tn 
% Row Count 10 (+ 4)
% Row 5
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\mymulticolumn{2}{x{5.377cm}}{{\bf{Complications}}} \tn 
% Row Count 11 (+ 1)
% Row 6
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\mymulticolumn{2}{x{5.377cm}}{- Increased viscosity of blood} \tn 
% Row Count 12 (+ 1)
% Row 7
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\mymulticolumn{2}{x{5.377cm}}{- Hemorrhage and thrombosis} \tn 
% Row Count 13 (+ 1)
% Row 8
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\mymulticolumn{2}{x{5.377cm}}{{\bf{Treatment}}} \tn 
% Row Count 14 (+ 1)
% Row 9
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\mymulticolumn{2}{x{5.377cm}}{- Phlebotomy} \tn 
% Row Count 15 (+ 1)
% Row 10
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\mymulticolumn{2}{x{5.377cm}}{- Myelosuppressive agents : Intron A, Agrylin, Aspirin} \tn 
% Row Count 17 (+ 2)
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\begin{tabularx}{5.377cm}{p{0.4977 cm} p{0.4977 cm} }
\SetRowColor{DarkBackground}
\mymulticolumn{2}{x{5.377cm}}{\bf\textcolor{white}{Idiopathic Thrombocytopenia Purpura (ITP)}}  \tn
% Row 0
\SetRowColor{LightBackground}
\mymulticolumn{2}{x{5.377cm}}{Disorder of decreased platelets (below 150,000)} \tn 
% Row Count 1 (+ 1)
% Row 1
\SetRowColor{white}
\mymulticolumn{2}{x{5.377cm}}{{\bf{Causes}}} \tn 
% Row Count 2 (+ 1)
% Row 2
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\mymulticolumn{2}{x{5.377cm}}{•Low production of platelets} \tn 
% Row Count 3 (+ 1)
% Row 3
\SetRowColor{white}
\mymulticolumn{2}{x{5.377cm}}{•Increased breakdown of platelets} \tn 
% Row Count 4 (+ 1)
% Row 4
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\mymulticolumn{2}{x{5.377cm}}{{\bf{Symptoms}}} \tn 
% Row Count 5 (+ 1)
% Row 5
\SetRowColor{white}
\mymulticolumn{2}{x{5.377cm}}{• Bruising, Nosebleeds, Petechiae} \tn 
% Row Count 6 (+ 1)
% Row 6
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\mymulticolumn{2}{x{5.377cm}}{{\bf{Immune Thrombocytopenic Purpura}}} \tn 
% Row Count 7 (+ 1)
% Row 7
\SetRowColor{white}
\mymulticolumn{2}{x{5.377cm}}{• Abnormal destruction of circulating platelets} \tn 
% Row Count 8 (+ 1)
% Row 8
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\mymulticolumn{2}{x{5.377cm}}{• Autoimmune disorder} \tn 
% Row Count 9 (+ 1)
% Row 9
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\mymulticolumn{2}{x{5.377cm}}{• Destroyed in hosts' spleen by macrophages} \tn 
% Row Count 10 (+ 1)
% Row 10
\SetRowColor{LightBackground}
\mymulticolumn{2}{x{5.377cm}}{{\bf{Thrombotic Thrombocytopenic Purpura}}} \tn 
% Row Count 11 (+ 1)
% Row 11
\SetRowColor{white}
\mymulticolumn{2}{x{5.377cm}}{• Increase agglutination of platelets, form microthrombi} \tn 
% Row Count 13 (+ 2)
% Row 12
\SetRowColor{LightBackground}
\mymulticolumn{2}{x{5.377cm}}{{\bf{Diagnostic Studies}}} \tn 
% Row Count 14 (+ 1)
% Row 13
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\mymulticolumn{2}{x{5.377cm}}{•Platelet count, Hgb/Hct, prothrombin time (PT)} \tn 
% Row Count 15 (+ 1)
% Row 14
\SetRowColor{LightBackground}
\mymulticolumn{2}{x{5.377cm}}{•Activated partial thromboplastin time (aPTT)} \tn 
% Row Count 16 (+ 1)
% Row 15
\SetRowColor{white}
\mymulticolumn{2}{x{5.377cm}}{{\bf{Treatments}}} \tn 
% Row Count 17 (+ 1)
% Row 16
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\mymulticolumn{2}{x{5.377cm}}{•Corticosteroids (Bethamethasone, prednisone, prelone)} \tn 
% Row Count 19 (+ 2)
% Row 17
\SetRowColor{white}
\mymulticolumn{2}{x{5.377cm}}{• Plasmapheresis, Splenectomy, platelet transfusion} \tn 
% Row Count 21 (+ 2)
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\par\addvspace{1.3em}


% That's all folks
\end{multicols*}

\end{document}