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% Document Info
\author{chihauhauu}
\pdfinfo{
  /Title (sas-1-basic-principles-of-pharmacology.pdf)
  /Creator (Cheatography)
  /Author (chihauhauu)
  /Subject (SAS \#1: Basic Principles of Pharmacology Cheat Sheet)
}

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\noindent
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    {\parbox{\dimexpr\textwidth-2\fboxsep\relax}{\noindent
        \hspace*{-6pt}\includegraphics[width=5.8cm]{/web/www.cheatography.com/public/images/cheatography_logo.pdf}}
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    \vspace{-2pt}\large{\bf{\textcolor{DarkBackground}{\textrm{SAS \#1: Basic Principles of Pharmacology Cheat Sheet}}}} \\
    \normalsize{by \textcolor{DarkBackground}{chihauhauu} via \textcolor{DarkBackground}{\uline{cheatography.com/197961/cs/41829/}}}
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  \mymulticolumn{2}{p{5.377cm}}{\bf\textcolor{white}{Cheatographer}}  \\
  \vspace{-2pt}chihauhauu \\
  \uline{cheatography.com/chihauhauu} \\
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  \mymulticolumn{1}{p{5.377cm}}{\bf\textcolor{white}{Cheat Sheet}}  \\
   \vspace{-2pt}Not Yet Published.\\
   Updated 22nd December, 2023.\\
   Page {\thepage} of \pageref{LastPage}.
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  Measure your website readability!\\
  www.readability-score.com
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\begin{multicols*}{3}

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\mymulticolumn{1}{x{5.377cm}}{\bf\textcolor{white}{Table 1-3}}  \tn
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\mymulticolumn{1}{x{5.377cm}}{\bf\textcolor{white}{Endocytosis and Exocytosis}}  \tn
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\mymulticolumn{1}{x{5.377cm}}{{\bf{Endocytosis}} - is the process by which the substance is bound at a cell-surface receptor, engulfed by the cell membrane, and carried into the cell by pinching off of the newly formed vesicle inside the membrane.} \tn 
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\mymulticolumn{1}{x{5.377cm}}{{\bf{Exocytosis}} - the reverse process. Is responsible for the secretion of many substances from cells.} \tn 
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\mymulticolumn{1}{x{5.377cm}}{\bf\textcolor{white}{Factors for a drug to cross the lipid membrane:}}  \tn
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\mymulticolumn{1}{x{5.377cm}}{- Lipid soluble} \tn 
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\mymulticolumn{1}{x{5.377cm}}{These are of 3 major types:} \tn 
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\mymulticolumn{1}{x{5.377cm}}{{\bf{ELECTROSTATIC bonds}} – more common but are weaker than covalent bonds.} \tn 
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\mymulticolumn{1}{x{5.377cm}}{\bf\textcolor{white}{THE TIME COURSE of DRUG EFFECT}}  \tn
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\mymulticolumn{1}{x{5.377cm}}{{\bf{IMMEDIATE EFFECTS}} – drug effects are directly related to plasma concentrations.} \tn 
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\mymulticolumn{1}{x{5.377cm}}{{\bf{DELAYED EFFECTS}} - Changes in drug effects are often delayed in relation to changes in plasma concentration. This delay may reflect the time required for the drug to distribute from plasma to the site of action.} \tn 
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\mymulticolumn{1}{x{5.377cm}}{{\bf{ CUMULATIVE EFFECTS}} - It is the accumulation of aminoglycoside in the renal cortex that is thought to cause renal damage.} \tn 
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% That's all folks
\end{multicols*}

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