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% Document Info
\author{Thomas Von Chao (chautommy93)}
\pdfinfo{
  /Title (clinmod-antihypertensive.pdf)
  /Creator (Cheatography)
  /Author (Thomas Von Chao (chautommy93))
  /Subject (ClinMod: Antihypertensive Cheat Sheet)
}

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        \hspace*{-6pt}\includegraphics[width=5.8cm]{/web/www.cheatography.com/public/images/cheatography_logo.pdf}}
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    \vspace{-2pt}\large{\bf{\textcolor{DarkBackground}{\textrm{ClinMod: Antihypertensive Cheat Sheet}}}} \\
    \normalsize{by \textcolor{DarkBackground}{Thomas Von Chao (chautommy93)} via \textcolor{DarkBackground}{\uline{cheatography.com/178810/cs/39909/}}}
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\noindent
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  \mymulticolumn{2}{p{5.377cm}}{\bf\textcolor{white}{Cheatographer}}  \\
  \vspace{-2pt}Thomas Von Chao (chautommy93) \\
  \uline{cheatography.com/chautommy93} \\
  \end{tabulary}
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  \mymulticolumn{1}{p{5.377cm}}{\bf\textcolor{white}{Cheat Sheet}}  \\
   \vspace{-2pt}Not Yet Published.\\
   Updated 17th August, 2023.\\
   Page {\thepage} of \pageref{LastPage}.
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  Measure your website readability!\\
  www.readability-score.com
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\begin{tabularx}{17.67cm}{x{8.2896 cm} x{8.9804 cm} }
\SetRowColor{DarkBackground}
\mymulticolumn{2}{x{17.67cm}}{\bf\textcolor{white}{Drug Classes of Anti-hypertensive}}  \tn
% Row 0
\SetRowColor{LightBackground}
Thiazides & - HCTZ 12.5 – 25 mg QD \{\{nl\}\} - Chlorthalidone 12.5 – 25 mg QD \tn 
% Row Count 4 (+ 4)
% Row 1
\SetRowColor{white}
Calcium Channel Blockers (CCBs) & - Amlodipine 5 – 10 mg QD \{\{nl\}\} - Diltiazem 180 – 360 mg QD \tn 
% Row Count 8 (+ 4)
% Row 2
\SetRowColor{LightBackground}
β-Blockers & - Metoprolol 25 – 200 mg QD \{\{nl\}\} - Carvedilol 12.5 – 50 mg BID \tn 
% Row Count 12 (+ 4)
% Row 3
\SetRowColor{white}
\seqsplit{Angiotensin-Converting} Enzyme (ACEIs) & Lisinopril 10 – 40 mg QD \tn 
% Row Count 14 (+ 2)
% Row 4
\SetRowColor{LightBackground}
\seqsplit{Angiotensin-Receptor} Blockers (ARBs) & Valsartan 80 – 320 mg QD \tn 
% Row Count 16 (+ 2)
% Row 5
\SetRowColor{white}
Renin Inhibitors & Aliskiren 150 – 300 mg QD \tn 
% Row Count 18 (+ 2)
% Row 6
\SetRowColor{LightBackground}
Aldosterone Receptor Blockers & - Spironolactone 25 mg – 50 mg QD \{\{nl\}\} - Eplerenone 25 – 50 mg QD \tn 
% Row Count 22 (+ 4)
% Row 7
\SetRowColor{white}
α1-Blockers & Doxazosin 2 – 8 mg QD at night \tn 
% Row Count 24 (+ 2)
% Row 8
\SetRowColor{LightBackground}
α2-Agonist & Clonidine 0.1 – 0.3 mg TID (Patch 0.1 – 0.3 mg QD) \tn 
% Row Count 27 (+ 3)
\hhline{>{\arrayrulecolor{DarkBackground}}--}
\end{tabularx}
\par\addvspace{1.3em}

\begin{tabularx}{17.67cm}{x{8.635 cm} x{8.635 cm} }
\SetRowColor{DarkBackground}
\mymulticolumn{2}{x{17.67cm}}{\bf\textcolor{white}{Mechanism of Action}}  \tn
% Row 0
\SetRowColor{LightBackground}
Thiazides: \{\{nl\}\} - Hydrochlorothiazide \{\{nl\}\} - Chlorthalidone & Inhibit Na+ reabsorption in distal tubule \tn 
% Row Count 4 (+ 4)
% Row 1
\SetRowColor{white}
Calcium Channel Blockers (CCBs): \{\{nl\}\} - Amlodipine (DPH) \{\{nl\}\} - Diltiazem (non-DPH) & BOTH: Inhibition of L-type Ca2+ channel \{\{nl\}\} NON-DPH: AV node conduction → ↑HR \tn 
% Row Count 9 (+ 5)
% Row 2
\SetRowColor{LightBackground}
β-Blockers: \{\{nl\}\} - Metoprolol \{\{nl\}\} - Carvedilol & Block NE at β-AR \tn 
% Row Count 12 (+ 3)
% Row 3
\SetRowColor{white}
\seqsplit{Angiotensin-Converting} Enzyme (ACEIs): \{\{nl\}\} - Lisinopril & Inhibit ACE production of Angiotensin-II (AngII) \tn 
% Row Count 15 (+ 3)
% Row 4
\SetRowColor{LightBackground}
\seqsplit{Angiotensin-Receptor} Blockers (ARBs): \{\{nl\}\} - Valsartan & Block Angiotensin-II (AngII) at AT1 receptor \tn 
% Row Count 18 (+ 3)
% Row 5
\SetRowColor{white}
Renin Inhibitors \{\{nl\}\} - Aliskiren & Inhibit renin production of Angiotensin-I (AngI) \tn 
% Row Count 21 (+ 3)
% Row 6
\SetRowColor{LightBackground}
Aldosterone Receptor Blockers: \{\{nl\}\} - Spironolactone \{\{nl\}\} - Eplerenone & Inhibit aldosterone receptor \tn 
% Row Count 25 (+ 4)
% Row 7
\SetRowColor{white}
α1-Blockers & Block NE at α-AR \tn 
% Row Count 26 (+ 1)
% Row 8
\SetRowColor{LightBackground}
α2-Agonist & Stimulate α2-AR (pre-synaptic) \tn 
% Row Count 28 (+ 2)
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\begin{tabularx}{17.67cm}{x{8.635 cm} x{8.635 cm} }
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\mymulticolumn{2}{x{17.67cm}}{\bf\textcolor{white}{Physiology}}  \tn
% Row 0
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Thiazides: \{\{nl\}\} - Hydrochlorothiazide \{\{nl\}\} - Chlorthalidone & Mild diuretic, but powerful antihypertensive \tn 
% Row Count 4 (+ 4)
% Row 1
\SetRowColor{white}
Calcium Channel Blockers (CCBs): \{\{nl\}\} - Amlodipine (DPH) \{\{nl\}\} - Diltiazem (non-DPH) & BOTH: Vasodilator (arterial) \{\{nl\}\} NON-DPH: ↓HR \& ↓CO \tn 
% Row Count 9 (+ 5)
% Row 2
\SetRowColor{LightBackground}
β-Blockers: \{\{nl\}\} - Metoprolol \{\{nl\}\} - Carvedilol & - Bradycardia (↓HR) \{\{nl\}\} - ↓contractility \tn 
% Row Count 12 (+ 3)
% Row 3
\SetRowColor{white}
\seqsplit{Angiotensin-Converting} Enzyme (ACEIs): \{\{nl\}\} - Lisinopril & Vasodilator \seqsplit{(arterial/venous/renal)} \tn 
% Row Count 15 (+ 3)
% Row 4
\SetRowColor{LightBackground}
\seqsplit{Angiotensin-Receptor} Blockers (ARBs): \{\{nl\}\} - Valsartan & Vasodilator \seqsplit{(arterial/venous/renal)} \tn 
% Row Count 18 (+ 3)
% Row 5
\SetRowColor{white}
Renin Inhibitors \{\{nl\}\} - Aliskiren & Vasodilator \seqsplit{(arterial/venous/renal)} \tn 
% Row Count 20 (+ 2)
% Row 6
\SetRowColor{LightBackground}
Aldosterone Receptor Blockers: \{\{nl\}\} - Spironolactone \{\{nl\}\} - Eplerenone & Mild diuretic \tn 
% Row Count 24 (+ 4)
% Row 7
\SetRowColor{white}
α1-Blockers & Vasodilator \tn 
% Row Count 25 (+ 1)
% Row 8
\SetRowColor{LightBackground}
α2-Agonist & - ↓HR \& ↓contractility \{\{nl\}\} - Vasodilation \tn 
% Row Count 28 (+ 3)
\hhline{>{\arrayrulecolor{DarkBackground}}--}
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\mymulticolumn{2}{x{17.67cm}}{\bf\textcolor{white}{Adverse Drug Reactions (ADRs)}}  \tn
% Row 0
\SetRowColor{LightBackground}
Thiazides: \{\{nl\}\} - Hydrochlorothiazide \{\{nl\}\} - Chlorthalidone & - Hypotension \{\{nl\}\} – \seqsplit{Hypovolemia/hyponatremia} \{\{nl\}\} – Hypokalemia \{\{nl\}\} – Hypercalcemia \{\{nl\}\} – Hyperuricemia \{\{nl\}\} – Lipid/glucose disturbances \tn 
% Row Count 8 (+ 8)
% Row 1
\SetRowColor{white}
Calcium Channel Blockers (CCBs): \{\{nl\}\} - Amlodipine (DPH) \{\{nl\}\} - Diltiazem (non-DPH) & - Hypotension \{\{nl\}\} – Peripheral edema \{\{nl\}\} – GI/Constipation \tn 
% Row Count 13 (+ 5)
% Row 2
\SetRowColor{LightBackground}
β-Blockers: \{\{nl\}\} - Metoprolol \{\{nl\}\} - Carvedilol & - Hypotension \{\{nl\}\} – Bradycardia \{\{nl\}\} – Fatigue \{\{nl\}\} – Sexual dysfunction \{\{nl\}\} – Lipid/glucose disturbances \tn 
% Row Count 20 (+ 7)
% Row 3
\SetRowColor{white}
\seqsplit{Angiotensin-Converting} Enzyme (ACEIs): \{\{nl\}\} - Lisinopril & - Cough (ACEIs only) \{\{nl\}\} – Hypotension (careful in volume depletion) \{\{nl\}\} – Hyperkalemia \{\{nl\}\} – Acute kidney injury \{\{nl\}\} – Angioedema (acute/chronic) \tn 
% Row Count 29 (+ 9)
% Row 4
\SetRowColor{LightBackground}
\seqsplit{Angiotensin-Receptor} Blockers (ARBs): \{\{nl\}\} - Valsartan & – Hypotension (careful in volume depletion) \{\{nl\}\} – Hyperkalemia \{\{nl\}\} – Acute kidney injury \{\{nl\}\} – Angioedema (acute/chronic) \tn 
% Row Count 36 (+ 7)
\end{tabularx}
\par\addvspace{1.3em}

\begin{tabularx}{17.67cm}{x{8.635 cm} x{8.635 cm} }
\SetRowColor{DarkBackground}
\mymulticolumn{2}{x{17.67cm}}{\bf\textcolor{white}{Adverse Drug Reactions (ADRs) (cont)}}  \tn
% Row 5
\SetRowColor{LightBackground}
Renin Inhibitors \{\{nl\}\} - Aliskiren & – Hypotension (careful in volume depletion) \{\{nl\}\} – Hyperkalemia \{\{nl\}\} – Acute kidney injury \{\{nl\}\} – Angioedema (?) \tn 
% Row Count 7 (+ 7)
% Row 6
\SetRowColor{white}
Aldosterone Receptor Blockers: \{\{nl\}\} - Spironolactone \{\{nl\}\} - Eplerenone & – Hypotension \{\{nl\}\} – Hyperkalemia \{\{nl\}\} – Acute kidney injury \{\{nl\}\} – Gynecomastia \tn 
% Row Count 12 (+ 5)
% Row 7
\SetRowColor{LightBackground}
α1-Blockers & – Orthostatic hypotension \{\{nl\}\} – Dizziness \{\{nl\}\} – Fatigue \{\{nl\}\} – Tolerance \tn 
% Row Count 17 (+ 5)
% Row 8
\SetRowColor{white}
α2-Agonist & – Hypotension \{\{nl\}\} – Bradycardia \{\{nl\}\} – Fatigue \{\{nl\}\} – Somnolence \{\{nl\}\} – Discontinuation syndrome!!!! \tn 
% Row Count 23 (+ 6)
\hhline{>{\arrayrulecolor{DarkBackground}}--}
\end{tabularx}
\par\addvspace{1.3em}



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