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% Document Info
\author{Claire Badawi (CB1)}
\pdfinfo{
  /Title (icu-drugs-crib.pdf)
  /Creator (Cheatography)
  /Author (Claire Badawi (CB1))
  /Subject (ICU Drugs Crib Cheat Sheet)
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\noindent
\begin{multicols}{3}
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    {\parbox{\dimexpr\textwidth-2\fboxsep\relax}{\noindent
        \hspace*{-6pt}\includegraphics[width=5.8cm]{/web/www.cheatography.com/public/images/cheatography_logo.pdf}}
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\begin{tabulary}{11cm}{L}
    \vspace{-2pt}\large{\bf{\textcolor{DarkBackground}{\textrm{ICU Drugs Crib Cheat Sheet}}}} \\
    \normalsize{by \textcolor{DarkBackground}{Claire Badawi (CB1)} via \textcolor{DarkBackground}{\uline{cheatography.com/121361/cs/22184/}}}
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\noindent
\begin{multicols}{3}
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  \mymulticolumn{2}{p{5.377cm}}{\bf\textcolor{white}{Cheatographer}}  \\
  \vspace{-2pt}Claire Badawi (CB1) \\
  \uline{cheatography.com/cb1} \\
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  \mymulticolumn{1}{p{5.377cm}}{\bf\textcolor{white}{Cheat Sheet}}  \\
   \vspace{-2pt}Published 27th March, 2020.\\
   Updated 27th March, 2020.\\
   Page {\thepage} of \pageref{LastPage}.
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  %\includegraphics[width=48px,height=48px]{dave.jpeg}
  Measure your website readability!\\
  www.readability-score.com
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\begin{document}
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\begin{multicols*}{3}

\begin{tabularx}{5.377cm}{x{1.00694 cm} x{1.78503 cm} x{1.78503 cm} }
\SetRowColor{DarkBackground}
\mymulticolumn{3}{x{5.377cm}}{\bf\textcolor{white}{Sedation/Analgesia Infusions}}  \tn
% Row 0
\SetRowColor{LightBackground}
{\bf{Drug}} & {\bf{Dose Range}} & {\bf{Additional information}} \tn 
% Row Count 2 (+ 2)
% Row 1
\SetRowColor{white}
\seqsplit{Fentanyl} IV & 25-400mcg/hr & Opiate of choice in renal impairment \tn 
% Row Count 5 (+ 3)
% Row 2
\SetRowColor{LightBackground}
\seqsplit{Propofol} IV & 0-300mg/hr Max 4mg/kg/hr (IBW) & Short acting. No analgesic properties. Hypotensive effect. \tn 
% Row Count 9 (+ 4)
% Row 3
\SetRowColor{white}
\seqsplit{Midazolam} IV & 0-10mg/hr & Accumulates in renal impairment and in obesity – may take days to clear \tn 
% Row Count 14 (+ 5)
% Row 4
\SetRowColor{LightBackground}
\seqsplit{Morphine} IV & 1-10mg/hr & Avoid use in renal impairment \tn 
% Row Count 16 (+ 2)
% Row 5
\SetRowColor{white}
\seqsplit{Thiopentone} IV & 3-8mg/kg/hr (ABW) & Used for raised ICP.  Risk of accumulation. Can cause disruption of potassium homeostasis. Aim K+ to be lower end of normal range \tn 
% Row Count 25 (+ 9)
% Row 6
\SetRowColor{LightBackground}
\seqsplit{Ketamine} IV \seqsplit{(analgesia)} & {\bf{Loading dose:}} 0.2mg/kg (ABW) STAT {\bf{Initial maintenance:}} 0.3mg/kg/hr (ABW) and titrate (up to 0.6mg/kg/hr) & May lower seizure threshold. Very hallucinogenic and can induce catatonia. NOT indicated for 'normal' acute pain. \tn 
% Row Count 33 (+ 8)
\hhline{>{\arrayrulecolor{DarkBackground}}---}
\SetRowColor{LightBackground}
\mymulticolumn{3}{x{5.377cm}}{Patients should ideally have EEG or BIS monitoring to assess level of sedation. \newline Ketamine: Different vial strengths and administration rates used for bronchospasm \& asthma vs analgesia.}  \tn 
\hhline{>{\arrayrulecolor{DarkBackground}}---}
\end{tabularx}
\par\addvspace{1.3em}

\begin{tabularx}{5.377cm}{x{0.86963 cm} x{0.96117 cm} x{2.7462 cm} }
\SetRowColor{DarkBackground}
\mymulticolumn{3}{x{5.377cm}}{\bf\textcolor{white}{Paralysis}}  \tn
% Row 0
\SetRowColor{LightBackground}
{\bf{Drug}} & {\bf{Dose Range}} & {\bf{Additional information}} \tn 
% Row Count 2 (+ 2)
% Row 1
\SetRowColor{white}
\seqsplit{Atracurium} &  & Used for cardiovascularly stable patients at low risk of bronchospasm. Histamine release. Short duration of action \tn 
% Row Count 7 (+ 5)
% Row 2
\SetRowColor{LightBackground}
\seqsplit{Cisatracurium} &  & Lacks histamine-releasing effects therefore used in cardiovascularly unstable patients at risk of bronchospasm. More potent \& slightly longer duration of action than atracurium \tn 
% Row Count 15 (+ 8)
% Row 3
\SetRowColor{white}
\seqsplit{Rocuronium} &  & Most rapid onset of non-depolarising agents \tn 
% Row Count 17 (+ 2)
\hhline{>{\arrayrulecolor{DarkBackground}}---}
\SetRowColor{LightBackground}
\mymulticolumn{3}{x{5.377cm}}{check local guidelines for dose ranges and availability of monitoring such as train of four and BIS. Be aware of renal function and dose adjustments.}  \tn 
\hhline{>{\arrayrulecolor{DarkBackground}}---}
\end{tabularx}
\par\addvspace{1.3em}

\begin{tabularx}{5.377cm}{p{0.59501 cm} x{2.01388 cm} x{1.96811 cm} }
\SetRowColor{DarkBackground}
\mymulticolumn{3}{x{5.377cm}}{\bf\textcolor{white}{Cardiovascular Drugs}}  \tn
% Row 0
\SetRowColor{LightBackground}
{\bf{Drug}} & {\bf{Dose Range}} & {\bf{Additional information}} \tn 
% Row Count 2 (+ 2)
% Row 1
\SetRowColor{white}
\seqsplit{Adenosine} & 3mg bolus & Rapid intravenous injection. If no response after 1-2 min, give 6mg. If no response after 1-2 min, give 12mg \tn 
% Row Count 9 (+ 7)
% Row 2
\SetRowColor{LightBackground}
\seqsplit{Amiodarone} & Loading dose of 300mg over 1 hour (prescribe as a STAT dose).   Then start infusion of 900mg over 23 hrs &  \tn 
% Row Count 16 (+ 7)
% Row 3
\SetRowColor{white}
\seqsplit{Digoxin} & IV/PO/Enteral loading dose of 0.5-1mg in 1-2 divided doses 4-8 hours apart, dependent on response & Maintenance dose 62.5-250 mcg/day depending on plasma levels and clinical response. Therapeutic plasma level 0.8 – 2microgram/L \tn 
% Row Count 24 (+ 8)
% Row 4
\SetRowColor{LightBackground}
GTN IV & 0.5-10 mg/hr & rw every 24hr due to ceiling effect \tn 
% Row Count 27 (+ 3)
% Row 5
\SetRowColor{white}
\seqsplit{Labetolol} IV & 15-120 mg/hr &  \tn 
% Row Count 30 (+ 3)
\hhline{>{\arrayrulecolor{DarkBackground}}---}
\end{tabularx}
\par\addvspace{1.3em}

\begin{tabularx}{5.377cm}{p{0.77809 cm} x{1.60195 cm} x{2.19696 cm} }
\SetRowColor{DarkBackground}
\mymulticolumn{3}{x{5.377cm}}{\bf\textcolor{white}{Inotropes/Vasopressors}}  \tn
% Row 0
\SetRowColor{LightBackground}
{\bf{Drug}} & {\bf{Dose Range}} & {\bf{Additional information}} \tn 
% Row Count 2 (+ 2)
% Row 1
\SetRowColor{white}
\seqsplit{Noradrenaline} & 0.01 – 1 mcg/kg/min (IBW) & \textgreater{}0.25mcg/kg/min – seek senior review \tn 
% Row Count 5 (+ 3)
% Row 2
\SetRowColor{LightBackground}
\seqsplit{Adrenaline} & 0.01 – 1 mcg/kg/min (IBW) & \textgreater{}0.25mcg/kg/min – seek senior review \tn 
% Row Count 7 (+ 2)
% Row 3
\SetRowColor{white}
\seqsplit{Dobutamine} & 2.5 – 20 mcg/kg/min (IBW) &  \tn 
% Row Count 9 (+ 2)
% Row 4
\SetRowColor{LightBackground}
\seqsplit{Terlipressin} & 0.05-0.2 mg/hour &  \tn 
% Row Count 11 (+ 2)
\hhline{>{\arrayrulecolor{DarkBackground}}---}
\SetRowColor{LightBackground}
\mymulticolumn{3}{x{5.377cm}}{Monitor for excessive peripheral vasoconstriction and raised lactate.}  \tn 
\hhline{>{\arrayrulecolor{DarkBackground}}---}
\end{tabularx}
\par\addvspace{1.3em}

\begin{tabularx}{5.377cm}{x{1.3731 cm} x{1.60195 cm} x{1.60195 cm} }
\SetRowColor{DarkBackground}
\mymulticolumn{3}{x{5.377cm}}{\bf\textcolor{white}{Respiratory}}  \tn
% Row 0
\SetRowColor{LightBackground}
{\bf{Drug}} & {\bf{Dose Range}} & {\bf{Additional information}} \tn 
% Row Count 2 (+ 2)
% Row 1
\SetRowColor{white}
\seqsplit{Aminophylline} IV & 5mg/kg  loading dose then 0.3-1 mg/kg/hr (IBW) & Patients taking oral theophylline / aminophylline should not receive a loading dose. Start continuous infusion at 0.5mg/kg/hr and adjust according to plasma theophylline concentration \tn 
% Row Count 16 (+ 14)
% Row 2
\SetRowColor{LightBackground}
Salbutamol IV & 0.18 – 1.2 mg/hr &  \tn 
% Row Count 18 (+ 2)
% Row 3
\SetRowColor{white}
\seqsplit{Epoprostenol} nebulised & 5 – 20 \seqsplit{nanograms/kg/min} (ABW) & For pulmonary hypertension or \seqsplit{hepato-pulmonary} syndrome \tn 
% Row Count 22 (+ 4)
% Row 4
\SetRowColor{LightBackground}
Ketamine IV \seqsplit{(Bronchospasm} \& asthma) & 0.5 – 2.5 mg/kg/hr (ABW) & Dose should be maintained at the minimum amount providing adequate response; increased adverse \seqsplit{cardiovascular} effects with increased dose \tn 
% Row Count 32 (+ 10)
\hhline{>{\arrayrulecolor{DarkBackground}}---}
\SetRowColor{LightBackground}
\mymulticolumn{3}{x{5.377cm}}{Ketamine: Different vial strengths and administration rates used for analgesia}  \tn 
\hhline{>{\arrayrulecolor{DarkBackground}}---}
\end{tabularx}
\par\addvspace{1.3em}

\begin{tabularx}{5.377cm}{x{1.21133 cm} p{0.71009 cm} x{1.21133 cm} x{1.04425 cm} }
\SetRowColor{DarkBackground}
\mymulticolumn{4}{x{5.377cm}}{\bf\textcolor{white}{VTE Prophylaxis}}  \tn
% Row 0
\SetRowColor{LightBackground}
{\bf{Renal function}} & {\bf{Drug}} & {\bf{Patient Weight (ABW)}} & {\bf{Dose}} \tn 
% Row Count 3 (+ 3)
% Row 1
\SetRowColor{white}
eGFR\textgreater{}   30ml/min & \seqsplit{Enoxaparin} S/C & \textless{}50kg & 20mg OD \tn 
% Row Count 6 (+ 3)
% Row 2
\SetRowColor{LightBackground}
 &  & 50-100kg & 40mg OD \tn 
% Row Count 7 (+ 1)
% Row 3
\SetRowColor{white}
 &  & 101-150kg & 80mg OD (or 40mg BD) \tn 
% Row Count 9 (+ 2)
% Row 4
\SetRowColor{LightBackground}
 &  & \textgreater{}150kg & 120mg OD (or 60mg BD) \tn 
% Row Count 12 (+ 3)
% Row 5
\SetRowColor{white}
eGFR \textless{}   30ml/min or RRT & \seqsplit{Heparin} S/C & \textless{}100kg & 5000 units BD \tn 
% Row Count 15 (+ 3)
% Row 6
\SetRowColor{LightBackground}
 &  & \textgreater{}100kg & 5000units TDS \tn 
% Row Count 17 (+ 2)
\hhline{>{\arrayrulecolor{DarkBackground}}----}
\end{tabularx}
\par\addvspace{1.3em}

\begin{tabularx}{5.377cm}{x{0.96117 cm} x{1.32733 cm} x{2.2885 cm} }
\SetRowColor{DarkBackground}
\mymulticolumn{3}{x{5.377cm}}{\bf\textcolor{white}{Prokinetics}}  \tn
% Row 0
\SetRowColor{LightBackground}
{\bf{Drug}} & {\bf{Dose Range}} & {\bf{Additional information}} \tn 
% Row Count 2 (+ 2)
% Row 1
\SetRowColor{white}
\seqsplit{Metoclopramide} IV & 10mg TDS (max 3-5 days) & Avoid long-term use, due to risk of neurological side effects \tn 
% Row Count 6 (+ 4)
% Row 2
\SetRowColor{LightBackground}
\seqsplit{Erythromycin} IV & 250mg 6hourly & Risk of prolonged QTc syndrome – daily ECGs \tn 
% Row Count 9 (+ 3)
\hhline{>{\arrayrulecolor{DarkBackground}}---}
\SetRowColor{LightBackground}
\mymulticolumn{3}{x{5.377cm}}{Review daily}  \tn 
\hhline{>{\arrayrulecolor{DarkBackground}}---}
\end{tabularx}
\par\addvspace{1.3em}

\begin{tabularx}{5.377cm}{p{0.4977 cm} p{0.4977 cm} }
\SetRowColor{DarkBackground}
\mymulticolumn{2}{x{5.377cm}}{\bf\textcolor{white}{Stress Ulcer Prophylaxis}}  \tn
% Row 0
\SetRowColor{LightBackground}
\mymulticolumn{2}{x{5.377cm}}{} \tn 
% Row Count 0 (+ 0)
\hhline{>{\arrayrulecolor{DarkBackground}}--}
\SetRowColor{LightBackground}
\mymulticolumn{2}{x{5.377cm}}{Pantoprazole 40mg IV OD or Omeprazole 40mg IV. \newline If patient is absorbing enteral feed for \textgreater{}24 hours or E+D, stop PPI or consider switch to PO PPI. }  \tn 
\hhline{>{\arrayrulecolor{DarkBackground}}--}
\end{tabularx}
\par\addvspace{1.3em}


% That's all folks
\end{multicols*}

\end{document}