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% Most of the following are not required for the majority
% of cheat sheets but are needed for some symbol support.
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% Document Info
\author{Carsonmccall}
\pdfinfo{
  /Title (immunology.pdf)
  /Creator (Cheatography)
  /Author (Carsonmccall)
  /Subject (Immunology Cheat Sheet)
}

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\fancyhead[L]{
\noindent
\begin{multicols}{3}
\begin{tabulary}{5.8cm}{C}
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    \vspace{-7pt}
    {\parbox{\dimexpr\textwidth-2\fboxsep\relax}{\noindent
        \hspace*{-6pt}\includegraphics[width=5.8cm]{/web/www.cheatography.com/public/images/cheatography_logo.pdf}}
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\columnbreak
\begin{tabulary}{11cm}{L}
    \vspace{-2pt}\large{\bf{\textcolor{DarkBackground}{\textrm{Immunology Cheat Sheet}}}} \\
    \normalsize{by \textcolor{DarkBackground}{Carsonmccall} via \textcolor{DarkBackground}{\uline{cheatography.com/209662/cs/45145/}}}
\end{tabulary}
\end{multicols}}

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\noindent
\begin{multicols}{3}
\begin{tabulary}{5.8cm}{LL}
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  \mymulticolumn{2}{p{5.377cm}}{\bf\textcolor{white}{Cheatographer}}  \\
  \vspace{-2pt}Carsonmccall \\
  \uline{cheatography.com/carsonmccall} \\
  \end{tabulary}
\vfill
\columnbreak
\begin{tabulary}{5.8cm}{L}
  \SetRowColor{FootBackground}
  \mymulticolumn{1}{p{5.377cm}}{\bf\textcolor{white}{Cheat Sheet}}  \\
   \vspace{-2pt}Not Yet Published.\\
   Updated 30th November, 2024.\\
   Page {\thepage} of \pageref{LastPage}.
\end{tabulary}
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  \vspace{-5pt}
  %\includegraphics[width=48px,height=48px]{dave.jpeg}
  Measure your website readability!\\
  www.readability-score.com
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\end{multicols}}




\begin{document}
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% www.emerson.emory.edu/services/latex/latex_169.html
\footnotesize % Small font.

\begin{multicols*}{3}

\begin{tabularx}{5.377cm}{x{1.29402 cm} x{3.68298 cm} }
\SetRowColor{DarkBackground}
\mymulticolumn{2}{x{5.377cm}}{\bf\textcolor{white}{IMPORTANT REMINDERS}}  \tn
% Row 0
\SetRowColor{LightBackground}
{\bf{Serum}} & Blood {\bf{W/O}} cells or Fibrinogen (clotting factor) \tn 
% Row Count 2 (+ 2)
% Row 1
\SetRowColor{white}
{\bf{Plasma}} & Blood {\bf{W}} Fibrinogen and water but \textasciitilde{} still {\bf{NO}} cells \tn 
% Row Count 4 (+ 2)
% Row 2
\SetRowColor{LightBackground}
{\bf{Buffy Coat}} & Separated blood layer containing WBCs and Platelets \tn 
% Row Count 6 (+ 2)
% Row 3
\SetRowColor{white}
{\bf{MHC}} & Major Histocompatibility Complex \tn 
% Row Count 8 (+ 2)
% Row 4
\SetRowColor{LightBackground}
{\bf{TCR}} & T-Cell receptor \tn 
% Row Count 9 (+ 1)
% Row 5
\SetRowColor{white}
{\bf{BCR}} & B-Cell receptor \tn 
% Row Count 10 (+ 1)
\hhline{>{\arrayrulecolor{DarkBackground}}--}
\end{tabularx}
\par\addvspace{1.3em}

\begin{tabularx}{5.377cm}{X}
\SetRowColor{DarkBackground}
\mymulticolumn{1}{x{5.377cm}}{\bf\textcolor{white}{PLASMA \textasciitilde{} in EDTA tube (purple top)}}  \tn
\SetRowColor{LightBackground}
\mymulticolumn{1}{p{5.377cm}}{\vspace{1px}\centerline{\includegraphics[width=5.1cm]{/web/www.cheatography.com/public/uploads/carsonmccall_1732842125_blood-components.png}}} \tn 
\hhline{>{\arrayrulecolor{DarkBackground}}-}
\SetRowColor{LightBackground}
\mymulticolumn{1}{x{5.377cm}}{- Anti-Coagulants are needed for purifying \newline - Can be prepared as soon as its centrifuged  \newline - {\bf{Fibrinogen = present}} \newline - Buffy coat can contaminate the liquidated fraction \newline - Composed of ions that is {\emph{representative of the circulating blood!}} \newline - Less stable}  \tn 
\hhline{>{\arrayrulecolor{DarkBackground}}-}
\end{tabularx}
\par\addvspace{1.3em}

\begin{tabularx}{5.377cm}{X}
\SetRowColor{DarkBackground}
\mymulticolumn{1}{x{5.377cm}}{\bf\textcolor{white}{SERUM \textasciitilde{} Red-Top Tube}}  \tn
\SetRowColor{LightBackground}
\mymulticolumn{1}{p{5.377cm}}{\vspace{1px}\centerline{\includegraphics[width=5.1cm]{/web/www.cheatography.com/public/uploads/carsonmccall_1732851017_Screenshot 2024-11-28 at 8.56.17 PM.png}}} \tn 
\hhline{>{\arrayrulecolor{DarkBackground}}-}
\SetRowColor{LightBackground}
\mymulticolumn{1}{x{5.377cm}}{- No Anticoagulants added \newline - 30 min delay for clot formation \newline - Fibrinogen absent \newline - Cleaner sample (lacks depleted cells and cell remnants) \newline - Contains antibodies, antigens, electrolytes and medications, hormones and microorganisms \newline - The study of serology involves the study of the serum as the GS}  \tn 
\hhline{>{\arrayrulecolor{DarkBackground}}-}
\end{tabularx}
\par\addvspace{1.3em}

\begin{tabularx}{5.377cm}{p{0.4577 cm} x{2.05965 cm} x{2.05965 cm} }
\SetRowColor{DarkBackground}
\mymulticolumn{3}{x{5.377cm}}{\bf\textcolor{white}{ANTIBODY CLASSES}}  \tn
% Row 0
\SetRowColor{LightBackground}
{\bf{CLASS}} & {\bf{DESCRIPTION}} & {\bf{NOTES}} \tn 
% Row Count 3 (+ 3)
% Row 1
\SetRowColor{white}
{\bf{IgG}} & Neutralizing Ab & mnemonic \textgreater{} "{\emph{grandmas memory}}" \tn 
% Row Count 5 (+ 2)
% Row 2
\SetRowColor{LightBackground}
 & {\bf{{\emph{!Made later in immune response!}}}} &  \tn 
% Row Count 8 (+ 3)
% Row 3
\SetRowColor{white}
 & {\bf{Primary}} Ab in {\emph{memory response}} &  \tn 
% Row Count 10 (+ 2)
% Row 4
\SetRowColor{LightBackground}
 & Found in blood &  \tn 
% Row Count 11 (+ 1)
% Row 5
\SetRowColor{white}
 & Small size (able to pass barriers easily) &  \tn 
% Row Count 14 (+ 3)
% Row 6
\SetRowColor{LightBackground}
 & 🌟🌟Highest in conc. in {\bf{Colostrum/Blood}} &  \tn 
% Row Count 17 (+ 3)
% Row 7
\SetRowColor{white}
 & Longer half-life than IgM &  \tn 
% Row Count 19 (+ 2)
% Row 8
\SetRowColor{LightBackground}
 & Bind phagocytes via {\bf{Fc region}} & {\emph{Opsonin}} \tn 
% Row Count 21 (+ 2)
% Row 9
\SetRowColor{white}
\mymulticolumn{3}{x{5.377cm}}{} \tn 
% Row Count 21 (+ 0)
% Row 10
\SetRowColor{LightBackground}
{\bf{IgM}} & 🌟🌟 {\bf{First Ig}} in primary response & mnemonic \textgreater{} "{\emph{I want MINE first}}" \tn 
% Row Count 24 (+ 3)
% Row 11
\SetRowColor{white}
 & Short half-life &  \tn 
% Row Count 25 (+ 1)
% Row 12
\SetRowColor{LightBackground}
 & 10 binding sites & \textgreater{} better {\bf{at aggregating than IgG}} \tn 
% Row Count 27 (+ 2)
% Row 13
\SetRowColor{white}
 &  & \textgreater{} {\bf{Neutralizing Ab}} \tn 
% Row Count 29 (+ 2)
% Row 14
\SetRowColor{LightBackground}
 & Large size & \textgreater{} can't penetrate tissue \tn 
% Row Count 31 (+ 2)
\end{tabularx}
\par\addvspace{1.3em}

\vfill
\columnbreak
\begin{tabularx}{5.377cm}{p{0.4577 cm} x{2.05965 cm} x{2.05965 cm} }
\SetRowColor{DarkBackground}
\mymulticolumn{3}{x{5.377cm}}{\bf\textcolor{white}{ANTIBODY CLASSES (cont)}}  \tn
% Row 15
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 &  & \textgreater{} confined to blood/lymph \tn 
% Row Count 2 (+ 2)
% Row 16
\SetRowColor{white}
 & {\bf{Activates {\emph{Compliment System}}}} &  \tn 
% Row Count 4 (+ 2)
% Row 17
\SetRowColor{LightBackground}
 & 🌟🌟 {\bf{High conc.  ==}} & {\bf{recent primary exposure}} \tn 
% Row Count 6 (+ 2)
% Row 18
\SetRowColor{white}
 & No {\bf{Fc receptor}} for IgM on phagocytes & {\emph{CANNOT}} act as an opsonin \tn 
% Row Count 9 (+ 3)
% Row 19
\SetRowColor{LightBackground}
\mymulticolumn{3}{x{5.377cm}}{} \tn 
% Row Count 9 (+ 0)
% Row 20
\SetRowColor{white}
{\bf{IgA}} & {\bf{!Important for mucosal protection!}} & mnemonic \textgreater{} "{\emph{Alpacas are snotty}}" \tn 
% Row Count 12 (+ 3)
% Row 21
\SetRowColor{LightBackground}
 & Dimeric form & \textgreater{} has a {\bf{secretory piece}} \tn 
% Row Count 14 (+ 2)
% Row 22
\SetRowColor{white}
 &  & \textasciitilde{} prevents degradation by Proteases \tn 
% Row Count 16 (+ 2)
% Row 23
\SetRowColor{LightBackground}
 &  & \textasciitilde{}🌟🌟 {\bf{secreted in MILK! (NOT ABSORBED THRU GUT)}} \tn 
% Row Count 20 (+ 4)
% Row 24
\SetRowColor{white}
 & 🌟🌟 Prevents epithelial adherence of bacti &  \tn 
% Row Count 23 (+ 3)
% Row 25
\SetRowColor{LightBackground}
 & Helps protect {\bf{neonate mucosa in:}} & \textgreater{} GIT \tn 
% Row Count 25 (+ 2)
% Row 26
\SetRowColor{white}
 &  & \textgreater{} respiratory \tn 
% Row Count 26 (+ 1)
% Row 27
\SetRowColor{LightBackground}
 &  & \textgreater{} UG tract \tn 
% Row Count 27 (+ 1)
% Row 28
\SetRowColor{white}
 & Found in: & \textgreater{} tears, saliva, and bile \tn 
% Row Count 29 (+ 2)
% Row 29
\SetRowColor{LightBackground}
\mymulticolumn{3}{x{5.377cm}}{} \tn 
% Row Count 29 (+ 0)
% Row 30
\SetRowColor{white}
{\bf{IgE}} & 🌟🌟 {\bf{!Important in adaptive resp. to {\emph{parasitic worms!}}}} & mnemonic \textgreater{} '{\emph{Ew worms and allergies}}" \tn 
% Row Count 33 (+ 4)
\end{tabularx}
\par\addvspace{1.3em}

\vfill
\columnbreak
\begin{tabularx}{5.377cm}{p{0.4577 cm} x{2.05965 cm} x{2.05965 cm} }
\SetRowColor{DarkBackground}
\mymulticolumn{3}{x{5.377cm}}{\bf\textcolor{white}{ANTIBODY CLASSES (cont)}}  \tn
% Row 31
\SetRowColor{LightBackground}
 & 🌟🌟 {\bf{Mediates Type-1 HS}} & \textgreater{} {\bf{Anaphylactic Shock}} \tn 
% Row Count 2 (+ 2)
% Row 32
\SetRowColor{white}
 & Mechanism:: & 1. {\bf{B-cells \textgreater{}}} make IgE to Ag \tn 
% Row Count 4 (+ 2)
% Row 33
\SetRowColor{LightBackground}
 &  & 2. {\bf{IgE \textgreater{}}} binds {\emph{Mast cells}} on their {\bf{Fc region}} \tn 
% Row Count 7 (+ 3)
% Row 34
\SetRowColor{white}
 &  & {\bf{Once exposed to Ag again:}} \tn 
% Row Count 9 (+ 2)
% Row 35
\SetRowColor{LightBackground}
 &  & 3. {\bf{IgE \textgreater{}}} binds {\emph{Mast cells}} \tn 
% Row Count 11 (+ 2)
% Row 36
\SetRowColor{white}
 &  & \textasciitilde{} 🌟🌟Activates {\emph{degranulation}} \tn 
% Row Count 13 (+ 2)
% Row 37
\SetRowColor{LightBackground}
 &  & 4. {\bf{Mast cells \textgreater{}}} 🌟🌟release {\emph{histamine}} \& vasoactive amines \tn 
% Row Count 17 (+ 4)
\hhline{>{\arrayrulecolor{DarkBackground}}---}
\end{tabularx}
\par\addvspace{1.3em}

\begin{tabularx}{5.377cm}{x{1.41887 cm} x{1.28156 cm} x{1.87657 cm} }
\SetRowColor{DarkBackground}
\mymulticolumn{3}{x{5.377cm}}{\bf\textcolor{white}{Neonatal Immunity}}  \tn
% Row 0
\SetRowColor{LightBackground}
 & {\bf{COLOSTRUM}} & {\bf{MILK}} \tn 
% Row Count 2 (+ 2)
% Row 1
\SetRowColor{white}
{\bf{Source of Ab}} & Dam's serum & Mammary gland \tn 
% Row Count 4 (+ 2)
% Row 2
\SetRowColor{LightBackground}
{\bf{Ig Composition}} & IgG (high conc.) & IgA (much smaller conc.) \tn 
% Row Count 6 (+ 2)
% Row 3
\SetRowColor{white}
\mymulticolumn{3}{x{5.377cm}}{**Prod.} \tn 
% Row Count 7 (+ 1)
\hhline{>{\arrayrulecolor{DarkBackground}}---}
\end{tabularx}
\par\addvspace{1.3em}


% That's all folks
\end{multicols*}

\end{document}