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% Document Info
\author{Carm (Carmilaa)}
\pdfinfo{
  /Title (hypertension-drugs.pdf)
  /Creator (Cheatography)
  /Author (Carm (Carmilaa))
  /Subject (Hypertension Drugs Cheat Sheet)
}

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\fancyhead[L]{
\noindent
\begin{multicols}{3}
\begin{tabulary}{5.8cm}{C}
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    \vspace{-7pt}
    {\parbox{\dimexpr\textwidth-2\fboxsep\relax}{\noindent
        \hspace*{-6pt}\includegraphics[width=5.8cm]{/web/www.cheatography.com/public/images/cheatography_logo.pdf}}
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\columnbreak
\begin{tabulary}{11cm}{L}
    \vspace{-2pt}\large{\bf{\textcolor{DarkBackground}{\textrm{Hypertension Drugs Cheat Sheet}}}} \\
    \normalsize{by \textcolor{DarkBackground}{Carm (Carmilaa)} via \textcolor{DarkBackground}{\uline{cheatography.com/49544/cs/16839/}}}
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\fancyfoot[L]{ \footnotesize
\noindent
\begin{multicols}{3}
\begin{tabulary}{5.8cm}{LL}
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  \mymulticolumn{2}{p{5.377cm}}{\bf\textcolor{white}{Cheatographer}}  \\
  \vspace{-2pt}Carm (Carmilaa) \\
  \uline{cheatography.com/carmilaa} \\
  \end{tabulary}
\vfill
\columnbreak
\begin{tabulary}{5.8cm}{L}
  \SetRowColor{FootBackground}
  \mymulticolumn{1}{p{5.377cm}}{\bf\textcolor{white}{Cheat Sheet}}  \\
   \vspace{-2pt}Published 28th August, 2018.\\
   Updated 28th August, 2018.\\
   Page {\thepage} of \pageref{LastPage}.
\end{tabulary}
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  %\includegraphics[width=48px,height=48px]{dave.jpeg}
  Measure your website readability!\\
  www.readability-score.com
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\begin{document}
\raggedright
\raggedcolumns

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\footnotesize % Small font.

\begin{multicols*}{4}

\begin{tabularx}{3.833cm}{x{1.06423 cm} x{2.36877 cm} }
\SetRowColor{DarkBackground}
\mymulticolumn{2}{x{3.833cm}}{\bf\textcolor{white}{{\bf{Introduction:}}}}  \tn
% Row 0
\SetRowColor{LightBackground}
\mymulticolumn{2}{x{3.833cm}}{\textgreater{} most common CVS disease} \tn 
% Row Count 1 (+ 1)
% Row 1
\SetRowColor{white}
\mymulticolumn{2}{x{3.833cm}}{\textgreater{} elevated arterial BP damages vessels in renal, heart and brain} \tn 
% Row Count 3 (+ 2)
% Row 2
\SetRowColor{LightBackground}
{\bf{Complications:}} & Renal failure, Coronary disease, Heart failure, Stroke, Diamentia \tn 
% Row Count 6 (+ 3)
\hhline{>{\arrayrulecolor{DarkBackground}}--}
\end{tabularx}
\par\addvspace{1.3em}

\begin{tabularx}{3.833cm}{x{1.2132 cm} x{0.84924 cm} x{0.97056 cm} }
\SetRowColor{DarkBackground}
\mymulticolumn{3}{x{3.833cm}}{\bf\textcolor{white}{{\bf{Classification:}}}}  \tn
% Row 0
\SetRowColor{LightBackground}
{\bf{Classification:}} & {\bf{Systolic BP}} & {\bf{Diastolic BP:}} \tn 
% Row Count 2 (+ 2)
% Row 1
\SetRowColor{white}
{\bf{Normal:}} & \textless{}120 & \textless{}80 \tn 
% Row Count 3 (+ 1)
% Row 2
\SetRowColor{LightBackground}
{\bf{Pre-hypertension:}} & 120-139 & 80-89 \tn 
% Row Count 5 (+ 2)
% Row 3
\SetRowColor{white}
{\bf{Stage 1 HTN:}} & 140-159 & 90-99 \tn 
% Row Count 6 (+ 1)
% Row 4
\SetRowColor{LightBackground}
{\bf{Stage 2 HTN:}} & \textgreater{}= 160 & \textgreater{}=100 \tn 
% Row Count 7 (+ 1)
\hhline{>{\arrayrulecolor{DarkBackground}}---}
\end{tabularx}
\par\addvspace{1.3em}

\begin{tabularx}{3.833cm}{x{1.64784 cm} x{1.78516 cm} }
\SetRowColor{DarkBackground}
\mymulticolumn{2}{x{3.833cm}}{\bf\textcolor{white}{{\bf{Types of Hypertension:}}}}  \tn
% Row 0
\SetRowColor{LightBackground}
{\bf{Essential Hypertension (85-90\%):}} & Primary hypertension, no identifiable cause (genetic), can't be cured, can be controlled \tn 
% Row Count 5 (+ 5)
% Row 1
\SetRowColor{white}
{\bf{ Secondary Hypertension (10-15\%):}} & Specific identified cause (comorbid disease or drug), can be cured when cause is eliminated \tn 
% Row Count 10 (+ 5)
\hhline{>{\arrayrulecolor{DarkBackground}}--}
\end{tabularx}
\par\addvspace{1.3em}

\begin{tabularx}{3.833cm}{x{1.61351 cm} x{1.81949 cm} }
\SetRowColor{DarkBackground}
\mymulticolumn{2}{x{3.833cm}}{\bf\textcolor{white}{{\bf{Secondary Causes of HTN:}}}}  \tn
% Row 0
\SetRowColor{LightBackground}
\mymulticolumn{2}{x{3.833cm}}{\textgreater{} Genetic factors} \tn 
% Row Count 1 (+ 1)
% Row 1
\SetRowColor{white}
\mymulticolumn{2}{x{3.833cm}}{\textgreater{} Psychological stress} \tn 
% Row Count 2 (+ 1)
% Row 2
\SetRowColor{LightBackground}
\textgreater{} Environmental and Dietary Factors: & high salt diet, decreased calcium and phosphate intake, sedentary lifestyle \tn 
% Row Count 6 (+ 4)
% Row 3
\SetRowColor{white}
\textgreater{} Diseases: & renal, endocrine, vascular, renal diseases \tn 
% Row Count 8 (+ 2)
% Row 4
\SetRowColor{LightBackground}
\textgreater{} Drugs: & sympathomimetic amines, amphetamines, oral decongestants (eg. pseudoehedrine), corticosteroids, osteogens (C0Cs), NSAIDs, COX-2 inhibitors \tn 
% Row Count 15 (+ 7)
\hhline{>{\arrayrulecolor{DarkBackground}}--}
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\par\addvspace{1.3em}

\begin{tabularx}{3.833cm}{x{0.92691 cm} x{2.50609 cm} }
\SetRowColor{DarkBackground}
\mymulticolumn{2}{x{3.833cm}}{\bf\textcolor{white}{{\bf{Clinical presentation:}}}}  \tn
% Row 0
\SetRowColor{LightBackground}
\mymulticolumn{2}{x{3.833cm}}{- Often incidental finding} \tn 
% Row Count 1 (+ 1)
% Row 1
\SetRowColor{white}
\mymulticolumn{2}{x{3.833cm}}{- Adults should get BP checks once a year} \tn 
% Row Count 2 (+ 1)
% Row 2
\SetRowColor{LightBackground}
- Severe cases: & {\bf{Headaches}}, visual disturbances, target organ damage (stroke, ischemic heart disease, renal failure) \tn 
% Row Count 6 (+ 4)
\hhline{>{\arrayrulecolor{DarkBackground}}--}
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\par\addvspace{1.3em}

\begin{tabularx}{3.833cm}{X}
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\mymulticolumn{1}{x{3.833cm}}{\bf\textcolor{white}{{\bf{Normal regulation of BP:}}}}  \tn
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\mymulticolumn{1}{p{3.833cm}}{\vspace{1px}\centerline{\includegraphics[width=5.1cm]{/web/www.cheatography.com/public/uploads/carmilaa_1535481138_BP1.PNG}}} \tn 
\hhline{>{\arrayrulecolor{DarkBackground}}-}
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\begin{tabularx}{3.833cm}{X}
\SetRowColor{DarkBackground}
\mymulticolumn{1}{x{3.833cm}}{\bf\textcolor{white}{{\bf{Factors Influencing BP:}}}}  \tn
\SetRowColor{LightBackground}
\mymulticolumn{1}{p{3.833cm}}{\vspace{1px}\centerline{\includegraphics[width=5.1cm]{/web/www.cheatography.com/public/uploads/carmilaa_1535481187_BP2.PNG}}} \tn 
\hhline{>{\arrayrulecolor{DarkBackground}}-}
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\par\addvspace{1.3em}

\begin{tabularx}{3.833cm}{x{1.61351 cm} x{1.81949 cm} }
\SetRowColor{DarkBackground}
\mymulticolumn{2}{x{3.833cm}}{\bf\textcolor{white}{{\bf{Potential Mechanisms of Parthogenesis:}}}}  \tn
% Row 0
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\mymulticolumn{2}{x{3.833cm}}{{\bf{BP= CO x PVR}}} \tn 
% Row Count 1 (+ 1)
% Row 1
\SetRowColor{white}
{\bf{Increased Cardiac output:}} & Increased fluid volume from excessive sodium intake or renal sodium retention Venous constriction: due to excess stimulation of RAAS \tn 
% Row Count 8 (+ 7)
% Row 2
\SetRowColor{LightBackground}
{\bf{Increased Peripheral resistance:}} & Excess stimulation of RAAS Sympathetic nervous system over-activity \tn 
% Row Count 12 (+ 4)
\hhline{>{\arrayrulecolor{DarkBackground}}--}
\end{tabularx}
\par\addvspace{1.3em}

\begin{tabularx}{3.833cm}{X}
\SetRowColor{DarkBackground}
\mymulticolumn{1}{x{3.833cm}}{\bf\textcolor{white}{{\bf{Antihypertensive Drugs:}}}}  \tn
\SetRowColor{LightBackground}
\mymulticolumn{1}{p{3.833cm}}{\vspace{1px}\centerline{\includegraphics[width=5.1cm]{/web/www.cheatography.com/public/uploads/carmilaa_1535481396_BP3.PNG}}} \tn 
\hhline{>{\arrayrulecolor{DarkBackground}}-}
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\par\addvspace{1.3em}

\begin{tabularx}{3.833cm}{x{1.33887 cm} x{2.09413 cm} }
\SetRowColor{DarkBackground}
\mymulticolumn{2}{x{3.833cm}}{\bf\textcolor{white}{{\bf{Classes of Antihypertensive Agents:}}}}  \tn
% Row 0
\SetRowColor{LightBackground}
\textgreater{} Diuretics: & Reduce blood volume=Depletes the body of sodium, Venodilation \tn 
% Row Count 3 (+ 3)
% Row 1
\SetRowColor{white}
\textgreater{} Sympathoplegic agents: & Reduce peripheral vascular resistance, Inhibit cardiac function, Increase venous pooling capacitance vessels \tn 
% Row Count 8 (+ 5)
% Row 2
\SetRowColor{LightBackground}
\textgreater{} Direct vasodilators: & Reduce peripheral vascular resistance, Increase venous pooling capacitance vessels \tn 
% Row Count 12 (+ 4)
% Row 3
\SetRowColor{white}
\textgreater{} Angiotensin antagonists: & Reduce peripheral vascular resistance, Reduce blood volume \tn 
% Row Count 15 (+ 3)
\hhline{>{\arrayrulecolor{DarkBackground}}--}
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\par\addvspace{1.3em}

\begin{tabularx}{3.833cm}{x{1.57918 cm} x{1.85382 cm} }
\SetRowColor{DarkBackground}
\mymulticolumn{2}{x{3.833cm}}{\bf\textcolor{white}{{\bf{Diuretics:}}}}  \tn
% Row 0
\SetRowColor{LightBackground}
\mymulticolumn{2}{x{3.833cm}}{- Reduce blood volume and cardiac output} \tn 
% Row Count 1 (+ 1)
% Row 1
\SetRowColor{white}
- Cardiac output returns to normal & But peripheral vascular resistance declines \tn 
% Row Count 4 (+ 3)
% Row 2
\SetRowColor{LightBackground}
- Sodium & Contributes to vascular resistance = Increase vessel stiffness \tn 
% Row Count 7 (+ 3)
% Row 3
\SetRowColor{white}
- Venodilation & Altered sodium-sodium calcium exchange \tn 
% Row Count 9 (+ 2)
\hhline{>{\arrayrulecolor{DarkBackground}}--}
\end{tabularx}
\par\addvspace{1.3em}

\begin{tabularx}{3.833cm}{X}
\SetRowColor{DarkBackground}
\mymulticolumn{1}{x{3.833cm}}{\bf\textcolor{white}{{\bf{Vasodilation mechanism by Diuretics:}}}}  \tn
\SetRowColor{LightBackground}
\mymulticolumn{1}{p{3.833cm}}{\vspace{1px}\centerline{\includegraphics[width=5.1cm]{/web/www.cheatography.com/public/uploads/carmilaa_1535481896_BP4.PNG}}} \tn 
\hhline{>{\arrayrulecolor{DarkBackground}}-}
\end{tabularx}
\par\addvspace{1.3em}

\begin{tabularx}{3.833cm}{X}
\SetRowColor{DarkBackground}
\mymulticolumn{1}{x{3.833cm}}{\bf\textcolor{white}{{\bf{Thiazide Diuretics:}}}}  \tn
\SetRowColor{LightBackground}
\mymulticolumn{1}{p{3.833cm}}{\vspace{1px}\centerline{\includegraphics[width=5.1cm]{/web/www.cheatography.com/public/uploads/carmilaa_1535481943_BP5.PNG}}} \tn 
\hhline{>{\arrayrulecolor{DarkBackground}}-}
\end{tabularx}
\par\addvspace{1.3em}

\begin{tabularx}{3.833cm}{X}
\SetRowColor{DarkBackground}
\mymulticolumn{1}{x{3.833cm}}{\bf\textcolor{white}{{\bf{Use of Diuretics:}}}}  \tn
% Row 0
\SetRowColor{LightBackground}
\mymulticolumn{1}{x{3.833cm}}{\textgreater{} Lower BP by 10-15 mmHg in most patients} \tn 
% Row Count 1 (+ 1)
% Row 1
\SetRowColor{white}
\mymulticolumn{1}{x{3.833cm}}{\textgreater{} Thiazide diuretics –mild to moderate HTN} \tn 
% Row Count 2 (+ 1)
% Row 2
\SetRowColor{LightBackground}
\mymulticolumn{1}{x{3.833cm}}{\textgreater{} Loop diuretics – severe HTN and hypertensive emergencies} \tn 
% Row Count 4 (+ 2)
\hhline{>{\arrayrulecolor{DarkBackground}}-}
\SetRowColor{LightBackground}
\mymulticolumn{1}{x{3.833cm}}{{\bf{ Adverse Effects (Thiazide Diuretics):}} \newline Potassium depletion – hypokalemia  \newline  \newline Magnesium depletion  \newline  \newline Hyperuricemia- gouty attacks  \newline  \newline Glucose intolerance  \newline  \newline Increase serum lipid concentrations}  \tn 
\hhline{>{\arrayrulecolor{DarkBackground}}-}
\end{tabularx}
\par\addvspace{1.3em}

\begin{tabularx}{3.833cm}{x{1.68217 cm} x{1.75083 cm} }
\SetRowColor{DarkBackground}
\mymulticolumn{2}{x{3.833cm}}{\bf\textcolor{white}{{\bf{ Sympathoplegic Drugs:}}}}  \tn
% Row 0
\SetRowColor{LightBackground}
{\bf{ Centrally-acting Drugs:}} & Methyldopa, clonidine \tn 
% Row Count 2 (+ 2)
% Row 1
\SetRowColor{white}
{\bf{Adrenoceptor antagonists}} & Beta-blockers, alpha-1 blockers \tn 
% Row Count 4 (+ 2)
% Row 2
\SetRowColor{LightBackground}
{\bf{ \seqsplit{Ganglionic-blocking} Agents:}} & No longer used clinically ; hexamethonium \tn 
% Row Count 7 (+ 3)
% Row 3
\SetRowColor{white}
{\bf{Adrenergic neuron blocking agents:}} & Block the release of noradrenaline, Reserpine, guanethidine, debrisoquin, Not/rarely used clinically \tn 
% Row Count 12 (+ 5)
\hhline{>{\arrayrulecolor{DarkBackground}}--}
\end{tabularx}
\par\addvspace{1.3em}

\begin{tabularx}{3.833cm}{x{1.68217 cm} x{1.75083 cm} }
\SetRowColor{DarkBackground}
\mymulticolumn{2}{x{3.833cm}}{\bf\textcolor{white}{{\bf{Centrally-Acting Drugs:}}}}  \tn
% Row 0
\SetRowColor{LightBackground}
- Methyldopa, clonidine & rarely used except clondine \tn 
% Row Count 2 (+ 2)
% Row 1
\SetRowColor{white}
\mymulticolumn{2}{x{3.833cm}}{- Reduces sympathetic outflow} \tn 
% Row Count 3 (+ 1)
% Row 2
\SetRowColor{LightBackground}
- Compensatory response mechanism: & salt retention \tn 
% Row Count 5 (+ 2)
% Row 3
\SetRowColor{white}
- {\bf{Clonidine}}, guanabenz, guanfacine & Stimulate central alpha-2 adrenoceptors \tn 
% Row Count 7 (+ 2)
% Row 4
\SetRowColor{LightBackground}
- Methyldopa – anologue of L-dopa & Results in the synthesis of a false neurotransmitter \tn 
% Row Count 10 (+ 3)
% Row 5
\SetRowColor{white}
 & \seqsplit{Alpha-methylnoradrenaline} = Stimulates central alpha-2 adrenoceptors \tn 
% Row Count 14 (+ 4)
\hhline{>{\arrayrulecolor{DarkBackground}}--}
\SetRowColor{LightBackground}
\mymulticolumn{2}{x{3.833cm}}{{\bf{Clonidine:}} \newline Reduces cardiac output, PVR, relaxation of capacitance vessels  \newline Rarely causes postural hypotension \newline Adverse effects: \newline - Dry mouth \newline - Sedation \newline Contraindication: Patients with depression  \newline {\bf{Caution: Abrupt discontinuation can lead to hypertensive crisis}}}  \tn 
\hhline{>{\arrayrulecolor{DarkBackground}}--}
\end{tabularx}
\par\addvspace{1.3em}

\begin{tabularx}{3.833cm}{x{1.44186 cm} x{1.99114 cm} }
\SetRowColor{DarkBackground}
\mymulticolumn{2}{x{3.833cm}}{\bf\textcolor{white}{{\bf{Adrenoceptor antagonists: Beta-blockers}}}}  \tn
% Row 0
\SetRowColor{LightBackground}
\mymulticolumn{2}{x{3.833cm}}{Non-selective: Propranolol} \tn 
% Row Count 1 (+ 1)
% Row 1
\SetRowColor{white}
Beta-1 selective: "BBEAM" & Betaxolol, bisoprolol, esoprolol, {\bf{atenolol, metoprolol}}, Cardioselective \tn 
% Row Count 5 (+ 4)
% Row 2
\SetRowColor{LightBackground}
Vasodilator beta-blockers & Also block alpha-1 receptors,Labetolol, carvidelol, nebivolol \tn 
% Row Count 8 (+ 3)
\hhline{>{\arrayrulecolor{DarkBackground}}--}
\SetRowColor{LightBackground}
\mymulticolumn{2}{x{3.833cm}}{{\bf{Decrease cardiac output}} \newline  \newline Decrease peripheral vascular resistance \newline  \newline Inhibit stimulation of  renin production by catecholamines  \newline  \newline Adverse effects= Heart block, bronchoconstriction, diabetes, vivid dreams}  \tn 
\hhline{>{\arrayrulecolor{DarkBackground}}--}
\end{tabularx}
\par\addvspace{1.3em}

\begin{tabularx}{3.833cm}{x{1.54485 cm} x{1.88815 cm} }
\SetRowColor{DarkBackground}
\mymulticolumn{2}{x{3.833cm}}{\bf\textcolor{white}{{\bf{Alpha-1 blockers:}}}}  \tn
% Row 0
\SetRowColor{LightBackground}
\mymulticolumn{2}{x{3.833cm}}{{\bf{Prazosin}}, terazosin, doxazosin} \tn 
% Row Count 1 (+ 1)
% Row 1
\SetRowColor{white}
\mymulticolumn{2}{x{3.833cm}}{Block alpha-1 receptors in arterioles and veins} \tn 
% Row Count 2 (+ 1)
% Row 2
\SetRowColor{LightBackground}
Vasodilation & Reduce peripheral resistance \tn 
% Row Count 4 (+ 2)
% Row 3
\SetRowColor{white}
Compensatory mechanism: & salt and water retention \tn 
% Row Count 6 (+ 2)
\hhline{>{\arrayrulecolor{DarkBackground}}--}
\SetRowColor{LightBackground}
\mymulticolumn{2}{x{3.833cm}}{More effective when used with other drugs}  \tn 
\hhline{>{\arrayrulecolor{DarkBackground}}--}
\end{tabularx}
\par\addvspace{1.3em}

\begin{tabularx}{3.833cm}{x{1.20155 cm} x{2.23145 cm} }
\SetRowColor{DarkBackground}
\mymulticolumn{2}{x{3.833cm}}{\bf\textcolor{white}{{\bf{Calcium Channel Blockers:}}}}  \tn
% Row 0
\SetRowColor{LightBackground}
\textgreater{} \seqsplit{Dihydropyridines} & amlodipine, isradipine, nicardipine, nimodipine, felodipine, nisoldipine, lacidipine \tn 
% Row Count 4 (+ 4)
% Row 1
\SetRowColor{white}
\textgreater{} \seqsplit{Non-dihydropyridines} & Verapamil, diltiazem, hydralazine \tn 
% Row Count 6 (+ 2)
% Row 2
\SetRowColor{LightBackground}
 & Benzothiazepine (diltiazem) \tn 
% Row Count 8 (+ 2)
\hhline{>{\arrayrulecolor{DarkBackground}}--}
\SetRowColor{LightBackground}
\mymulticolumn{2}{x{3.833cm}}{{\bf{Mechanism of action:}} \newline - Inhibit calcium influx through voltage-dependent L-type calcium channels \newline - Relax arteriolar smooth muscle, reduce peripheral vascular resistance \newline - Cause coronary and peripheral vasodilation}  \tn 
\hhline{>{\arrayrulecolor{DarkBackground}}--}
\end{tabularx}
\par\addvspace{1.3em}

\begin{tabularx}{3.833cm}{x{1.7165 cm} x{1.7165 cm} }
\SetRowColor{DarkBackground}
\mymulticolumn{2}{x{3.833cm}}{\bf\textcolor{white}{{\bf{CCB: Mechanisms of Action:}}}}  \tn
% Row 0
\SetRowColor{LightBackground}
Dihydropyridine CCBs & Primary vasodilators (reduce PVR), All decrease cardiac contractility except amlodipine and felodipine \tn 
% Row Count 6 (+ 6)
% Row 1
\SetRowColor{white}
\seqsplit{Non-dihydropyridines} (diltiazem, verapamil) & directly block the AV node, decrease heart rate,decrease cardiac contraction \tn 
% Row Count 10 (+ 4)
% Row 2
\SetRowColor{LightBackground}
{\bf{Adverse effects:}} & 1. {\bf{Flushing, peripheral oedema, tachycardia, bradycardia, heartblock}} \tn 
% Row Count 14 (+ 4)
\hhline{>{\arrayrulecolor{DarkBackground}}--}
\SetRowColor{LightBackground}
\mymulticolumn{2}{x{3.833cm}}{2. {\bf{Headache}}, flushing, dizziness, palpitations, hypotension \newline occur within a few hours of dosing, Associated w high initial doses or rapid increase in dose, Common with short-acting preparations \newline 3. Ankle oedema: Due to a rise in intracapillary pressure as a result of selective dilatation of precapillary arterioles, NOT due to sodium retention, Relieved by bed rest \newline 4. {\bf{Gum Hypertrophy:}} dihydropyridines \newline 5. GIT: constipation (verapamil), nausea, and vomiting}  \tn 
\hhline{>{\arrayrulecolor{DarkBackground}}--}
\end{tabularx}
\par\addvspace{1.3em}

\begin{tabularx}{3.833cm}{x{1.7165 cm} x{1.7165 cm} }
\SetRowColor{DarkBackground}
\mymulticolumn{2}{x{3.833cm}}{\bf\textcolor{white}{{\bf{Inhibitors of Angiotensin:}}}}  \tn
% Row 0
\SetRowColor{LightBackground}
Angiotensin converting enzyme inhibitors (ACEIs) & Captopril, enalapril, Ramipril, fosinopril, trandopril \tn 
% Row Count 3 (+ 3)
% Row 1
\SetRowColor{white}
Angiotensin receptor blockers (ARBs) & Losartan, valsartan, telmisartan, irbesartan, candesartan \tn 
% Row Count 6 (+ 3)
% Row 2
\SetRowColor{LightBackground}
Renin-inhibitors & Aliskiren \tn 
% Row Count 7 (+ 1)
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\end{tabularx}
\par\addvspace{1.3em}

\begin{tabularx}{3.833cm}{X}
\SetRowColor{DarkBackground}
\mymulticolumn{1}{x{3.833cm}}{\bf\textcolor{white}{{\bf{Inhibitors of Angiotensin:}}}}  \tn
\SetRowColor{LightBackground}
\mymulticolumn{1}{p{3.833cm}}{\vspace{1px}\centerline{\includegraphics[width=5.1cm]{/web/www.cheatography.com/public/uploads/carmilaa_1535484450_BP6.PNG}}} \tn 
\hhline{>{\arrayrulecolor{DarkBackground}}-}
\SetRowColor{LightBackground}
\mymulticolumn{1}{x{3.833cm}}{{\bf{Adverse Effects}} \newline ACEIs = \newline Dry cough \newline Can cause hyperkalemia – potassium monitoring essential \newline Angioedema (substance P?)  \newline  \newline ARBs = \newline No dry cough \newline {\bf{Hyperkalemia}} \newline Angiodema is less common than ACEIs \newline  \newline Contraindicated in pregnancy}  \tn 
\hhline{>{\arrayrulecolor{DarkBackground}}-}
\end{tabularx}
\par\addvspace{1.3em}

\begin{tabularx}{3.833cm}{X}
\SetRowColor{DarkBackground}
\mymulticolumn{1}{x{3.833cm}}{\bf\textcolor{white}{{\bf{Combination Treatment: Vasodilators:}}}}  \tn
\SetRowColor{LightBackground}
\mymulticolumn{1}{p{3.833cm}}{\vspace{1px}\centerline{\includegraphics[width=5.1cm]{/web/www.cheatography.com/public/uploads/carmilaa_1535484504_BP7.PNG}}} \tn 
\hhline{>{\arrayrulecolor{DarkBackground}}-}
\end{tabularx}
\par\addvspace{1.3em}

\begin{tabularx}{3.833cm}{X}
\SetRowColor{DarkBackground}
\mymulticolumn{1}{x{3.833cm}}{\bf\textcolor{white}{{\bf{Management Approach:}}}}  \tn
\SetRowColor{LightBackground}
\mymulticolumn{1}{p{3.833cm}}{\vspace{1px}\centerline{\includegraphics[width=5.1cm]{/web/www.cheatography.com/public/uploads/carmilaa_1535484825_BP8.PNG}}} \tn 
\hhline{>{\arrayrulecolor{DarkBackground}}-}
\SetRowColor{LightBackground}
\mymulticolumn{1}{x{3.833cm}}{{\bf{First-line agents: "ACD" drugs:}} \newline - A: ACEIs and ARBs \newline - C: Calcium channel antagonists \newline - D: Diuretics (Thiazides) \newline  \newline {\bf{Second-line agents:}} \newline - {\bf{Beta-adrenoceptor blockers}} \newline - Aldosterone antagonists (spironolactone, eplerenone) \newline - Alpha-blockers (doxazosin, prazosin, terazosin) \newline - Loop diuretics (frusemide, torsemide) \newline - Direct vasodilators (hydralazine, minoxidil) {[}last-line of therapy{]} \newline - Central α-2 agonists (clonidine) \newline - Adrenergic antagonists (reserpine)}  \tn 
\hhline{>{\arrayrulecolor{DarkBackground}}-}
\end{tabularx}
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% That's all folks
\end{multicols*}

\end{document}