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% Document Info
\author{Anais.charles}
\pdfinfo{
  /Title (hematophaties-malignes.pdf)
  /Creator (Cheatography)
  /Author (Anais.charles)
  /Subject (HEMATOPHATIES MALIGNES Cheat Sheet)
}

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\noindent
\begin{multicols}{3}
\begin{tabulary}{5.8cm}{C}
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    \vspace{-7pt}
    {\parbox{\dimexpr\textwidth-2\fboxsep\relax}{\noindent
        \hspace*{-6pt}\includegraphics[width=5.8cm]{/web/www.cheatography.com/public/images/cheatography_logo.pdf}}
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\columnbreak
\begin{tabulary}{11cm}{L}
    \vspace{-2pt}\large{\bf{\textcolor{DarkBackground}{\textrm{HEMATOPHATIES MALIGNES Cheat Sheet}}}} \\
    \normalsize{by \textcolor{DarkBackground}{Anais.charles} via \textcolor{DarkBackground}{\uline{cheatography.com/167720/cs/35463/}}}
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\noindent
\begin{multicols}{3}
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  \mymulticolumn{2}{p{5.377cm}}{\bf\textcolor{white}{Cheatographer}}  \\
  \vspace{-2pt}Anais.charles \\
  \uline{cheatography.com/anais-charles} \\
  \end{tabulary}
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\columnbreak
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  \mymulticolumn{1}{p{5.377cm}}{\bf\textcolor{white}{Cheat Sheet}}  \\
   \vspace{-2pt}Published 14th November, 2022.\\
   Updated 14th November, 2022.\\
   Page {\thepage} of \pageref{LastPage}.
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  %\includegraphics[width=48px,height=48px]{dave.jpeg}
  Measure your website readability!\\
  www.readability-score.com
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\begin{document}
\raggedright
\raggedcolumns

% Set font size to small. Switch to any value
% from this page to resize cheat sheet text:
% www.emerson.emory.edu/services/latex/latex_169.html
\footnotesize % Small font.

\begin{multicols*}{2}

\begin{tabularx}{8.4cm}{x{3.52 cm} x{4.48 cm} }
\SetRowColor{DarkBackground}
\mymulticolumn{2}{x{8.4cm}}{\bf\textcolor{white}{{\bf{DEFINITIONS}}}}  \tn
% Row 0
\SetRowColor{LightBackground}
{\bf{HEMOPATHIE MYÉLOÏDE}} & Proliferation des cellules d'origine médullaires. \tn 
% Row Count 3 (+ 3)
% Row 1
\SetRowColor{white}
{\bf{HEMOPATHIE LYMPHOÏDE}} & Proliferation des cellules lymphoïdes et plasmocytaires \tn 
% Row Count 6 (+ 3)
% Row 2
\SetRowColor{LightBackground}
{\bf{HEMOSARCOME}} & Hemopathie maligne = cellule cancéreuse. Dans le cadre des sarcomes/cancer des tissus conjonctif. \tn 
% Row Count 11 (+ 5)
% Row 3
\SetRowColor{white}
{\bf{LEUCEMIES}} & Proliferations malignes des cellules leucocytaires, se manifestant dan sla moelle et le plus souvent également dans le sang. \tn 
% Row Count 17 (+ 6)
% Row 4
\SetRowColor{LightBackground}
{\bf{MYELOMES}} & Proliferations malignes localisées dans la moelle osseuse. \tn 
% Row Count 20 (+ 3)
% Row 5
\SetRowColor{white}
{\bf{LYMPHOIDES}} & Proliferations malignes des cellules constitutives des organes lymphoïdes secondaires, restant localisées dans ces mêmes organes. \tn 
% Row Count 26 (+ 6)
% Row 6
\SetRowColor{LightBackground}
{\bf{SYNDROME MYELOPROLIFERATIF}} & Proliferation anarchique (non-contrôlée) d'au moins une lignée myéloïde avec maturation et passage des cellules dans le sang \tn 
% Row Count 32 (+ 6)
\end{tabularx}
\par\addvspace{1.3em}

\vfill
\columnbreak
\begin{tabularx}{8.4cm}{x{3.52 cm} x{4.48 cm} }
\SetRowColor{DarkBackground}
\mymulticolumn{2}{x{8.4cm}}{\bf\textcolor{white}{{\bf{DEFINITIONS}} (cont)}}  \tn
% Row 7
\SetRowColor{LightBackground}
{\bf{SYNDROME LYMPHOPROLIFERATIF}} & Proliferation maligne avec maintient de la maturation, implication des lignées lymphocytaires \tn 
% Row Count 5 (+ 5)
\hhline{>{\arrayrulecolor{DarkBackground}}--}
\end{tabularx}
\par\addvspace{1.3em}

\begin{tabularx}{8.4cm}{X}
\SetRowColor{DarkBackground}
\mymulticolumn{1}{x{8.4cm}}{\bf\textcolor{white}{{\bf{LEUCEMIE AIGUE (LA)}}}}  \tn
\SetRowColor{white}
\mymulticolumn{1}{x{8.4cm}}{Proliferation maligne monoclonale.  \newline % Row Count 1 (+ 1)
Précurseurs hematopeietiques appelés leucobastes.  \newline % Row Count 3 (+ 2)
Capacités de maturation inexistantes ou tres restreinte = absence de cellules mûres de la lignée correspondante.% Row Count 6 (+ 3)
} \tn 
\hhline{>{\arrayrulecolor{DarkBackground}}-}
\end{tabularx}
\par\addvspace{1.3em}

\begin{tabularx}{8.4cm}{X}
\SetRowColor{DarkBackground}
\mymulticolumn{1}{x{8.4cm}}{\bf\textcolor{white}{{\bf{LA}}}}  \tn
\SetRowColor{LightBackground}
\mymulticolumn{1}{p{8.4cm}}{\vspace{1px}\centerline{\includegraphics[width=5.1cm]{/web/www.cheatography.com/public/uploads/anais-charles_1668421811_FF34C58D-A117-48A9-A897-A3C9C2E394F6.jpeg}}} \tn 
\hhline{>{\arrayrulecolor{DarkBackground}}-}
\SetRowColor{LightBackground}
\mymulticolumn{1}{x{8.4cm}}{La prolifération des {\bf{cellules jeunes bloquées}} dans leur maturation, envahit la moelle osseuse au dépend de {\bf{l'hematopoeise normale}}. \newline  \newline {\bf{Frequence}} : 3/100 000 cas par ans chez l'enfant (LAL) et chez l'adulte (LAM) \newline  \newline Ceci engendre une insuffisance médullaire : {\bf{anémie et thrombopénie}}}  \tn 
\hhline{>{\arrayrulecolor{DarkBackground}}-}
\end{tabularx}
\par\addvspace{1.3em}

\begin{tabularx}{8.4cm}{X}
\SetRowColor{DarkBackground}
\mymulticolumn{1}{x{8.4cm}}{\bf\textcolor{white}{{\bf{LA DIAGNOSTIC}}}}  \tn
% Row 0
\SetRowColor{LightBackground}
\mymulticolumn{1}{x{8.4cm}}{{\bf{Hemogramme}}} \tn 
% Row Count 1 (+ 1)
% Row 1
\SetRowColor{white}
\mymulticolumn{1}{x{8.4cm}}{{\bf{Myelogramme }}} \tn 
% Row Count 2 (+ 1)
\hhline{>{\arrayrulecolor{DarkBackground}}-}
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\par\addvspace{1.3em}

\begin{tabularx}{8.4cm}{X}
\SetRowColor{DarkBackground}
\mymulticolumn{1}{x{8.4cm}}{\bf\textcolor{white}{{\bf{ LA MYELOGRAMME}}}}  \tn
\SetRowColor{LightBackground}
\mymulticolumn{1}{p{8.4cm}}{\vspace{1px}\centerline{\includegraphics[width=5.1cm]{/web/www.cheatography.com/public/uploads/anais-charles_1668422471_FC58F1D8-3BD5-439E-A8D7-579221F9BA49.jpeg}}} \tn 
\hhline{>{\arrayrulecolor{DarkBackground}}-}
\SetRowColor{LightBackground}
\mymulticolumn{1}{x{8.4cm}}{Un envahissement par des cellules blastique, 30\% de cellules nucléées dans une moelle riche.}  \tn 
\hhline{>{\arrayrulecolor{DarkBackground}}-}
\end{tabularx}
\par\addvspace{1.3em}

\begin{tabularx}{8.4cm}{X}
\SetRowColor{DarkBackground}
\mymulticolumn{1}{x{8.4cm}}{\bf\textcolor{white}{{\bf{LA  HEMOGRAMME}}}}  \tn
% Row 0
\SetRowColor{LightBackground}
\mymulticolumn{1}{x{8.4cm}}{Anemie normochrome, normocytaire et aregenerative, une thrombopénie et neutropenie.} \tn 
% Row Count 2 (+ 2)
% Row 1
\SetRowColor{white}
\mymulticolumn{1}{x{8.4cm}}{Nombre de leucocyte variable : leucopenie à une hyperleucocytose} \tn 
% Row Count 4 (+ 2)
% Row 2
\SetRowColor{LightBackground}
\mymulticolumn{1}{x{8.4cm}}{Blastes avec caractères morphologique témoignant de leur jeune âge et de leur malignité.} \tn 
% Row Count 6 (+ 2)
\hhline{>{\arrayrulecolor{DarkBackground}}-}
\end{tabularx}
\par\addvspace{1.3em}

\begin{tabularx}{8.4cm}{X}
\SetRowColor{DarkBackground}
\mymulticolumn{1}{x{8.4cm}}{\bf\textcolor{white}{{\bf{LEUCEMIE LYMPHOÏDE CHRONIQUE (LCC)}}}}  \tn
\SetRowColor{white}
\mymulticolumn{1}{x{8.4cm}}{{\bf{Syndrome lymphoproliferatif}} (voir def). \newline % Row Count 1 (+ 1)
Une {\bf{proliferation maligne monoclonale}}, constituée de lymphocytes B.  \newline % Row Count 3 (+ 2)
{\bf{LB matures}} mais anormaux : {\bf{bloqués }}dans leur différenciation et n'aboutissent pas a la formation des {\bf{plasmocytes}}.% Row Count 6 (+ 3)
} \tn 
\hhline{>{\arrayrulecolor{DarkBackground}}-}
\end{tabularx}
\par\addvspace{1.3em}

\begin{tabularx}{8.4cm}{X}
\SetRowColor{DarkBackground}
\mymulticolumn{1}{x{8.4cm}}{\bf\textcolor{white}{{\bf{LCC}}}}  \tn
\SetRowColor{LightBackground}
\mymulticolumn{1}{p{8.4cm}}{\vspace{1px}\centerline{\includegraphics[width=5.1cm]{/web/www.cheatography.com/public/uploads/anais-charles_1668419288_F8AF911E-CC98-40F6-9B0C-70810947413D.jpeg}}} \tn 
\hhline{>{\arrayrulecolor{DarkBackground}}-}
\SetRowColor{LightBackground}
\mymulticolumn{1}{x{8.4cm}}{Fréquence : 25\% des leucémies}  \tn 
\hhline{>{\arrayrulecolor{DarkBackground}}-}
\end{tabularx}
\par\addvspace{1.3em}

\begin{tabularx}{8.4cm}{X}
\SetRowColor{DarkBackground}
\mymulticolumn{1}{x{8.4cm}}{\bf\textcolor{white}{{\bf{LCC DIAGNOSTIC}}}}  \tn
% Row 0
\SetRowColor{LightBackground}
\mymulticolumn{1}{x{8.4cm}}{{\bf{Hemogramme}}} \tn 
% Row Count 1 (+ 1)
% Row 1
\SetRowColor{white}
\mymulticolumn{1}{x{8.4cm}}{{\bf{Myelogramme}}} \tn 
% Row Count 2 (+ 1)
% Row 2
\SetRowColor{LightBackground}
\mymulticolumn{1}{x{8.4cm}}{{\bf{Bilan immunologique}}} \tn 
% Row Count 3 (+ 1)
\hhline{>{\arrayrulecolor{DarkBackground}}-}
\end{tabularx}
\par\addvspace{1.3em}

\begin{tabularx}{8.4cm}{X}
\SetRowColor{DarkBackground}
\mymulticolumn{1}{x{8.4cm}}{\bf\textcolor{white}{{\bf{LCC BILAN IMMUNOLOGIQUE}}}}  \tn
\SetRowColor{white}
\mymulticolumn{1}{x{8.4cm}}{\textgreater{} un tapage lymphocytaire montrant le nombre important de LN avec immunoglobuline de surface (montre le caractère monoclonal) \newline % Row Count 3 (+ 3)
\textgreater{} une étude des globunie sériques montrant une {\bf{hypogrammaglobulinemie}} \newline % Row Count 5 (+ 2)
\textgreater{} recherche d'{\bf{auto-anticorps}} (anti-GR et anti-plaquette) se traduisant par une {\bf{anémie hémolytique ou une thrombopénie}}.% Row Count 8 (+ 3)
} \tn 
\hhline{>{\arrayrulecolor{DarkBackground}}-}
\end{tabularx}
\par\addvspace{1.3em}

\begin{tabularx}{8.4cm}{X}
\SetRowColor{DarkBackground}
\mymulticolumn{1}{x{8.4cm}}{\bf\textcolor{white}{{\bf{LCC HEMOGRAMME}}}}  \tn
% Row 0
\SetRowColor{LightBackground}
\mymulticolumn{1}{x{8.4cm}}{GR et plaquettes {\bf{normaux}}} \tn 
% Row Count 1 (+ 1)
% Row 1
\SetRowColor{white}
\mymulticolumn{1}{x{8.4cm}}{{\bf{Hyperleucocytose}} : 50G/L à 100G/L} \tn 
% Row Count 2 (+ 1)
% Row 2
\SetRowColor{LightBackground}
\mymulticolumn{1}{x{8.4cm}}{{\bf{Lymphocytose}} (taux de lymphocytes élevé)} \tn 
% Row Count 3 (+ 1)
\hhline{>{\arrayrulecolor{DarkBackground}}-}
\end{tabularx}
\par\addvspace{1.3em}

\begin{tabularx}{8.4cm}{X}
\SetRowColor{DarkBackground}
\mymulticolumn{1}{x{8.4cm}}{\bf\textcolor{white}{{\bf{LCC MYELOGRAMME}}}}  \tn
\SetRowColor{white}
\mymulticolumn{1}{x{8.4cm}}{Une nette infiltration lymphocytaire \textgreater{} 40\% de lymphocyte dans une moelle riche.% Row Count 2 (+ 2)
} \tn 
\hhline{>{\arrayrulecolor{DarkBackground}}-}
\end{tabularx}
\par\addvspace{1.3em}

\begin{tabularx}{8.4cm}{x{3.28 cm} x{4.72 cm} }
\SetRowColor{DarkBackground}
\mymulticolumn{2}{x{8.4cm}}{\bf\textcolor{white}{{\bf{PERSISTANCE DE MATURATION}}}}  \tn
% Row 0
\SetRowColor{LightBackground}
{\bf{SYNDROMES PROLIFERATIONS}} & La prolifération coexiste avec une persistance de la maturation. \tn 
% Row Count 3 (+ 3)
% Row 1
\SetRowColor{white}
{\bf{LEUCEMIES AIGUËS}} & La prolifération malignes s'accompagne d'un blocage de la maturation. \tn 
% Row Count 7 (+ 4)
\hhline{>{\arrayrulecolor{DarkBackground}}--}
\end{tabularx}
\par\addvspace{1.3em}

\begin{tabularx}{8.4cm}{X}
\SetRowColor{DarkBackground}
\mymulticolumn{1}{x{8.4cm}}{\bf\textcolor{white}{{\bf{HEMOSARCOMES}}}}  \tn
\SetRowColor{LightBackground}
\mymulticolumn{1}{p{8.4cm}}{\vspace{1px}\centerline{\includegraphics[width=5.1cm]{/web/www.cheatography.com/public/uploads/anais-charles_1668417617_8586C36D-AB74-4FEF-8797-95B7C297C20E.jpeg}}} \tn 
\hhline{>{\arrayrulecolor{DarkBackground}}-}
\end{tabularx}
\par\addvspace{1.3em}

\begin{tabularx}{8.4cm}{X}
\SetRowColor{DarkBackground}
\mymulticolumn{1}{x{8.4cm}}{\bf\textcolor{white}{{\bf{LEUCEMIE MYÉLOÏDE CHRONIQUE (LMC)}}}}  \tn
\SetRowColor{white}
\mymulticolumn{1}{x{8.4cm}}{Syndrome myeoloproliferatif ( Voir def) \newline % Row Count 1 (+ 1)
Anomalie acquise d'une cellules souche multipotente qui entraine une proliferation anarchique (lignée granuleuse).  \newline % Row Count 4 (+ 3)
Les cellules prolifèrent dans la moelle osseuse et la rate puis passent dans le sang.% Row Count 6 (+ 2)
} \tn 
\hhline{>{\arrayrulecolor{DarkBackground}}-}
\SetRowColor{LightBackground}
\mymulticolumn{1}{x{8.4cm}}{MALADIE RARE}  \tn 
\hhline{>{\arrayrulecolor{DarkBackground}}-}
\end{tabularx}
\par\addvspace{1.3em}

\begin{tabularx}{8.4cm}{x{2.16 cm} x{5.84 cm} }
\SetRowColor{DarkBackground}
\mymulticolumn{2}{x{8.4cm}}{\bf\textcolor{white}{{\bf{LMC}}}}  \tn
% Row 0
\SetRowColor{LightBackground}
{\bf{MONOCLONALE}} & Une cellule mal-formée (l'origine de la pathologie) \tn 
% Row Count 2 (+ 2)
% Row 1
\SetRowColor{white}
{\bf{CAUSE}} & Une anomalie chromosomique acquise, specifique de la LCM, elle peut évolué vers une leucemie aigue. \tn 
% Row Count 6 (+ 4)
% Row 2
\SetRowColor{LightBackground}
{\bf{ACQUISE}} & Qui nest pas congénitale donc acquit au cours de la vie. \tn 
% Row Count 8 (+ 2)
\hhline{>{\arrayrulecolor{DarkBackground}}--}
\end{tabularx}
\par\addvspace{1.3em}

\begin{tabularx}{8.4cm}{X}
\SetRowColor{DarkBackground}
\mymulticolumn{1}{x{8.4cm}}{\bf\textcolor{white}{{\bf{LMC}}}}  \tn
\SetRowColor{LightBackground}
\mymulticolumn{1}{p{8.4cm}}{\vspace{1px}\centerline{\includegraphics[width=5.1cm]{/web/www.cheatography.com/public/uploads/anais-charles_1668420979_7BE13922-C4BA-4429-85B5-41532715A4E7.jpeg}}} \tn 
\hhline{>{\arrayrulecolor{DarkBackground}}-}
\end{tabularx}
\par\addvspace{1.3em}

\begin{tabularx}{8.4cm}{X}
\SetRowColor{DarkBackground}
\mymulticolumn{1}{x{8.4cm}}{\bf\textcolor{white}{{\bf{LMC DIAGNOSTIC}}}}  \tn
% Row 0
\SetRowColor{LightBackground}
\mymulticolumn{1}{x{8.4cm}}{{\bf{1. Hemogramme}}} \tn 
% Row Count 1 (+ 1)
% Row 1
\SetRowColor{white}
\mymulticolumn{1}{x{8.4cm}}{{\bf{2. Étude cytogénétique}}} \tn 
% Row Count 2 (+ 1)
% Row 2
\SetRowColor{LightBackground}
\mymulticolumn{1}{x{8.4cm}}{{\bf{3. Taux de phosphatase}}} \tn 
% Row Count 3 (+ 1)
% Row 3
\SetRowColor{white}
\mymulticolumn{1}{x{8.4cm}}{{\bf{4. Myelogramme}}} \tn 
% Row Count 4 (+ 1)
\hhline{>{\arrayrulecolor{DarkBackground}}-}
\end{tabularx}
\par\addvspace{1.3em}

\begin{tabularx}{8.4cm}{X}
\SetRowColor{DarkBackground}
\mymulticolumn{1}{x{8.4cm}}{\bf\textcolor{white}{{\bf{LMC ÉTUDE CYTOGÉNÉTIQUE}}}}  \tn
\SetRowColor{LightBackground}
\mymulticolumn{1}{p{8.4cm}}{\vspace{1px}\centerline{\includegraphics[width=5.1cm]{/web/www.cheatography.com/public/uploads/anais-charles_1668420689_6943D9CF-69AF-4C48-B06B-CF81034A743F.jpeg}}} \tn 
\hhline{>{\arrayrulecolor{DarkBackground}}-}
\SetRowColor{LightBackground}
\mymulticolumn{1}{x{8.4cm}}{Établissement du {\bf{carytoype}} sur les {\bf{cellules myéloïdes}} montrent dans 95\% de cas une {\bf{translocation des deux chromosomes 22 et 9}}.}  \tn 
\hhline{>{\arrayrulecolor{DarkBackground}}-}
\end{tabularx}
\par\addvspace{1.3em}

\begin{tabularx}{8.4cm}{X}
\SetRowColor{DarkBackground}
\mymulticolumn{1}{x{8.4cm}}{\bf\textcolor{white}{{\bf{LMC HEMOGRAMME}}}}  \tn
% Row 0
\SetRowColor{LightBackground}
\mymulticolumn{1}{x{8.4cm}}{{\bf{Anémie}} modérée normochrome, normocytaire et aregenerative.} \tn 
% Row Count 2 (+ 2)
% Row 1
\SetRowColor{white}
\mymulticolumn{1}{x{8.4cm}}{{\bf{Légère thrombocytose}} : nbr de plaquette normale ou tres augmenté. Présence de macroplaquette} \tn 
% Row Count 4 (+ 2)
% Row 2
\SetRowColor{LightBackground}
\mymulticolumn{1}{x{8.4cm}}{Nombre de leucocytes : {\bf{50G/L à 500G/L}}} \tn 
% Row Count 5 (+ 1)
% Row 3
\SetRowColor{white}
\mymulticolumn{1}{x{8.4cm}}{{\bf{Neutrophilie}} considerable avec une {\bf{myelemie}} importante a tout les stades} \tn 
% Row Count 7 (+ 2)
% Row 4
\SetRowColor{LightBackground}
\mymulticolumn{1}{x{8.4cm}}{{\bf{Oesunophilie}} ou {\bf{basophilie}} fréquentes} \tn 
% Row Count 8 (+ 1)
\hhline{>{\arrayrulecolor{DarkBackground}}-}
\end{tabularx}
\par\addvspace{1.3em}

\begin{tabularx}{8.4cm}{X}
\SetRowColor{DarkBackground}
\mymulticolumn{1}{x{8.4cm}}{\bf\textcolor{white}{{\bf{LMC TAUX DE PHOSPHATASE}}}}  \tn
\SetRowColor{white}
\mymulticolumn{1}{x{8.4cm}}{Mesurer le taux de {\bf{phosphase alcaline leucocytaire}}. Il doit {\bf{diminué}}.% Row Count 2 (+ 2)
} \tn 
\hhline{>{\arrayrulecolor{DarkBackground}}-}
\end{tabularx}
\par\addvspace{1.3em}

\begin{tabularx}{8.4cm}{X}
\SetRowColor{DarkBackground}
\mymulticolumn{1}{x{8.4cm}}{\bf\textcolor{white}{{\bf{LMC MYELOGRAMME}}}}  \tn
\SetRowColor{white}
\mymulticolumn{1}{x{8.4cm}}{Myelogramme : etude de la {\bf{moelle osseuse}} \newline % Row Count 1 (+ 1)
Montre une moelle très riche envahit par la {\bf{lignée granuleuse}} (la pyramide de maturation est respectée).% Row Count 4 (+ 3)
} \tn 
\hhline{>{\arrayrulecolor{DarkBackground}}-}
\end{tabularx}
\par\addvspace{1.3em}


% That's all folks
\end{multicols*}

\end{document}