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% Document Info
\author{adrianao}
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  /Title (monoamine-oxidase-inhibitors.pdf)
  /Creator (Cheatography)
  /Author (adrianao)
  /Subject (Monoamine Oxidase Inhibitors Cheat Sheet)
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    {\parbox{\dimexpr\textwidth-2\fboxsep\relax}{\noindent
        \hspace*{-6pt}\includegraphics[width=5.8cm]{/web/www.cheatography.com/public/images/cheatography_logo.pdf}}
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    \vspace{-2pt}\large{\bf{\textcolor{DarkBackground}{\textrm{Monoamine Oxidase Inhibitors Cheat Sheet}}}} \\
    \normalsize{by \textcolor{DarkBackground}{adrianao} via \textcolor{DarkBackground}{\uline{cheatography.com/168237/cs/35312/}}}
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  \mymulticolumn{2}{p{5.377cm}}{\bf\textcolor{white}{Cheatographer}}  \\
  \vspace{-2pt}adrianao \\
  \uline{cheatography.com/adrianao} \\
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  \mymulticolumn{1}{p{5.377cm}}{\bf\textcolor{white}{Cheat Sheet}}  \\
   \vspace{-2pt}Published 7th November, 2022.\\
   Updated 7th November, 2022.\\
   Page {\thepage} of \pageref{LastPage}.
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  Measure your website readability!\\
  www.readability-score.com
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\begin{multicols*}{3}

\begin{tabularx}{5.377cm}{X}
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\mymulticolumn{1}{x{5.377cm}}{\bf\textcolor{white}{Medications}}  \tn
% Row 0
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\mymulticolumn{1}{x{5.377cm}}{Phenelzine} \tn 
% Row Count 1 (+ 1)
% Row 1
\SetRowColor{white}
\mymulticolumn{1}{x{5.377cm}}{Isocarboxazid} \tn 
% Row Count 2 (+ 1)
% Row 2
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\mymulticolumn{1}{x{5.377cm}}{Tranylcypromine} \tn 
% Row Count 3 (+ 1)
% Row 3
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\mymulticolumn{1}{x{5.377cm}}{Selegiline (Transdermal MAOI)} \tn 
% Row Count 4 (+ 1)
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\begin{tabularx}{5.377cm}{X}
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\mymulticolumn{1}{x{5.377cm}}{\bf\textcolor{white}{Purpose}}  \tn
% Row 0
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\mymulticolumn{1}{x{5.377cm}}{These medications block MAOI enzymes in the brain, thereby increasing the amount of norepinephrine, dopamine, serotonin, and tyramine available for transmission of impulses.} \tn 
% Row Count 4 (+ 4)
% Row 1
\SetRowColor{white}
\mymulticolumn{1}{x{5.377cm}}{An increased amount of these neurotransmitters at nerve endings intensifies responses and relieves depression.} \tn 
% Row Count 7 (+ 3)
% Row 2
\SetRowColor{LightBackground}
\mymulticolumn{1}{x{5.377cm}}{However, the increase in tyramine can cause heightened blood pressure or hypertensive crisis if dietary and medication restrictions are not implemented.} \tn 
% Row Count 11 (+ 4)
% Row 3
\SetRowColor{white}
\mymulticolumn{1}{x{5.377cm}}{Onset of therapeutic action is not immediate, and usually takes 2 to 4 weeks.} \tn 
% Row Count 13 (+ 2)
% Row 4
\SetRowColor{LightBackground}
\mymulticolumn{1}{x{5.377cm}}{Less frequently used in comparison to other antidepressants due to food/drug interactions and adverse effects.} \tn 
% Row Count 16 (+ 3)
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\mymulticolumn{1}{x{5.377cm}}{\bf\textcolor{white}{Therapeutic Uses}}  \tn
% Row 0
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\mymulticolumn{1}{x{5.377cm}}{Depression} \tn 
% Row Count 1 (+ 1)
% Row 1
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% Row 2
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% Row Count 3 (+ 1)
% Row 3
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\mymulticolumn{1}{x{5.377cm}}{Social Anxiety Disorder} \tn 
% Row Count 4 (+ 1)
% Row 4
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\mymulticolumn{1}{x{5.377cm}}{Generalized anxiety Disorder} \tn 
% Row Count 5 (+ 1)
% Row 5
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\mymulticolumn{1}{x{5.377cm}}{Obsessive Compulsive Disorder} \tn 
% Row Count 6 (+ 1)
% Row 6
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\mymulticolumn{1}{x{5.377cm}}{Post-traumatic Stress Disorder} \tn 
% Row Count 7 (+ 1)
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\begin{tabularx}{5.377cm}{x{2.4885 cm} x{2.4885 cm} }
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\mymulticolumn{2}{x{5.377cm}}{\bf\textcolor{white}{Complications}}  \tn
% Row 0
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CNS Depression & Nursing Action and Education \tn 
% Row Count 2 (+ 2)
% Row 1
\SetRowColor{white}
Anxiety, agitation, mania, or hypomania & Observe for effects and notify the provider if they occur \tn 
% Row Count 5 (+ 3)
% Row 2
\SetRowColor{LightBackground}
Orthostatic Hypotension & Monitor blood pressure and heart rate for orthostatic changes. Hold medication and and notify the provider of significant changes. Instruct the client to change positions slowly. \tn 
% Row Count 14 (+ 9)
% Row 3
\SetRowColor{white}
Hypertensive crisis (resulting from intake of dietary tyramine, which could lead to a cerebral vascular accident) Severe hypertension (as a result of intensive vasoconstriction and stimulation of the heart), headache, nausea, increased heart rate, and increased blood pressure. & Administer phentolamine IV (a rapid-acting alpha-adrenergic blocker) or nifedipine SL. Provide continuous cardiac monitoring and respiratory support as indicated \tn 
% Row Count 28 (+ 14)
% Row 4
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Local rash with transdermal preparation & Choose a clean, dry area for each application. Apply a topical glucocorticoid on the affected area \tn 
% Row Count 33 (+ 5)
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\mymulticolumn{1}{x{5.377cm}}{\bf\textcolor{white}{Contraindications/ Precautions}}  \tn
% Row 0
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\mymulticolumn{1}{x{5.377cm}}{MAOIs are a pregnancy risk category C. Not generally recommended for use during pregnancy or breastfeeding. Notify the provider and they will determine if the risks of taking the medication out-weigh the benefits} \tn 
% Row Count 5 (+ 5)
% Row 1
\SetRowColor{white}
\mymulticolumn{1}{x{5.377cm}}{Contraindicated in clients taking SSRIs and in those who have pheochromocytoma, heart failure, cardiovascular, and cerebral vascular disease, and serve renal insufficiency.} \tn 
% Row Count 9 (+ 4)
% Row 2
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\mymulticolumn{1}{x{5.377cm}}{Use cautiously in clients who have diabetes and seizure disorders or those taking TCAs} \tn 
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% Row 3
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\mymulticolumn{1}{x{5.377cm}}{Transdermal selegiline is contraindicated for clients taking carbamazepine or oxcarbazepine, which can increase blood levels of the MAOIs} \tn 
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\mymulticolumn{2}{x{5.377cm}}{\bf\textcolor{white}{Interactions}}  \tn
% Row 0
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Interaction & Client Education and Nursing Action \tn 
% Row Count 2 (+ 2)
% Row 1
\SetRowColor{white}
Indirect-acting sympathomimetic medications (ephedrine, amphetamine) promote the release of norepinephrine and can lead to hypertensive crisis & Avoid over the counter decongestants and cold remedies, which frequently contain medications with sympathomimetic action \tn 
% Row Count 10 (+ 8)
% Row 2
\SetRowColor{LightBackground}
Use of tricyclic antidepressants can lead to hypertensive crisis & Use MAOIs and TCAs cautiously \tn 
% Row Count 14 (+ 4)
% Row 3
\SetRowColor{white}
Use of SSRIs can lead to serotonin syndrome & Avoid concurrent use \tn 
% Row Count 17 (+ 3)
% Row 4
\SetRowColor{LightBackground}
Antihypertensives have an additive hypotensive effects & Monitor blood pressure. Notify the provider if there is a significant drop in blood pressure. A reduced dosage of antihypertensive can be indicated \tn 
% Row Count 25 (+ 8)
% Row 5
\SetRowColor{white}
Use of meperidine can lead to hyperpyrexia & Use an alternative analgesic \tn 
% Row Count 28 (+ 3)
% Row 6
\SetRowColor{LightBackground}
Tyramine rich foods (aged cheese, avocados, salami, figs, bananas) can lead to hypertensive crisis & Assess for ability to follow strict adherence to dietary restrictions. Provide clients with written instructions regarding foods and beverages to avoid. Monitor for manifestations and notify the provider if they occur. Avoid taking any medications without approval of the provider. Dietary and medication restrictions should be continued for 2 weeks after the MAOIs have been discontinued. \tn 
% Row Count 48 (+ 20)
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\mymulticolumn{2}{x{5.377cm}}{\bf\textcolor{white}{Interactions (cont)}}  \tn
% Row 7
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Concurrent use of vasopressors (phenylethylamine, caffeine) can result in hypertension & Avoid foods that contain these agents (caffeinated drinks, chocolate, fava beans, ginseng) \tn 
% Row Count 5 (+ 5)
% Row 8
\SetRowColor{white}
General anesthetics & MAOIs should not be used within 10 to 14 days before or after surgery. \tn 
% Row Count 9 (+ 4)
\hhline{>{\arrayrulecolor{DarkBackground}}--}
\end{tabularx}
\par\addvspace{1.3em}


% That's all folks
\end{multicols*}

\end{document}